B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade von Kim, Sangwoo S., Shen, Sarek, Miyauchi, Sayuri, Sanders, P. Dominick, Franiak-Pietryga, Ida, Mell, Loren, Gutkind, J. Silvio, Cohen, Ezra E. W., Califano, Joseph A., Sharabi, Andrew B.

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Role of B Cells in Responses to Checkpoint Blockade Immunotherapy and Overall Survival of Cancer Patients von Kim, Sangwoo S., Sumner, Whitney A., Miyauchi, Sayuri, Cohen, Ezra E. W., Califano, Joseph A., Sharabi, Andrew B.

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Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics von Miyauchi, Sayuri, Kim, Sangwoo S, Pang, John, Gold, Kathryn A, Gutkind, J Silvio, Califano, Joseph A, Mell, Loren K, Cohen, Ezra E W, Sharabi, Andrew B

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Positive Surgical Margins in the 10 Most Common Solid Cancers von Orosco, Ryan K., Tapia, Viridiana J., Califano, Joseph A., Clary, Bryan, Cohen, Ezra E. W., Kane, Christopher, Lippman, Scott M., Messer, Karen, Molinolo, Alfredo, Murphy, James D., Pang, John, Sacco, Assuntina, Tringale, Kathryn R., Wallace, Anne, Nguyen, Quyen T.

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Serum microRNA biomarkers for detection of non-small cell lung cancer von Hennessey, Patrick T, Sanford, Tiffany, Choudhary, Ashish, Mydlarz, Wojciech W, Brown, David, Adai, Alex Tamas, Ochs, Michael F, Ahrendt, Steven A, Mambo, Elizabeth, Califano, Joseph A

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Transoral Surgery in HPV‐Positive Oropharyngeal Carcinoma: Oncologic Outcomes in the Veterans Affairs System von Faraji, Farhoud, Kumar, Abhishek, Voora, Rohith, Soliman, Shady I., Cherry, Daniel, Courtney, P. Travis, Finegersh, Andrey, Guo, Theresa, Cohen, Ezra, Califano, Joseph A., Mell, Loren, Rose, Brent, Orosco, Ryan K.

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Cannabinoids Promote Progression of HPV-Positive Head and Neck Squamous Cell Carcinoma via p38 MAPK Activation von Liu, Chao, Sadat, Sayed H., Ebisumoto, Koji, Sakai, Akihiro, Panuganti, Bharat A., Ren, Shuling, Goto, Yusuke, Haft, Sunny, Fukusumi, Takahito, Ando, Mizuo, Saito, Yuki, Guo, Theresa, Tamayo, Pablo, Yeerna, Huwate, Kim, William, Hubbard, Jacqueline, Sharabi, Andrew B., Gutkind, J. Silvio, Califano, Joseph A.

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HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers von Ren, Shuling, Gaykalova, Daria A., Guo, Theresa, Favorov, Alexander V., Fertig, Elana J., Tamayo, Pablo, Callejas-Valera, Juan Luis, Allevato, Mike, Gilardi, Mara, Santos, Jessica, Fukusumi, Takahito, Sakai, Akihiro, Ando, Mizuo, Sadat, Sayed, Liu, Chao, Xu, Guorong, Fisch, Kathleen M., Wang, Zhiyong, Molinolo, Alfredo A., Gutkind, J. Silvio, Ideker, Trey, Koch, Wayne M., Califano, Joseph A.

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Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC von Saddawi-Konefka, Robert, O’Farrell, Aoife, Faraji, Farhoud, Clubb, Lauren, Allevato, Michael M., Jensen, Shawn M., Yung, Bryan S., Wang, Zhiyong, Wu, Victoria H., Anang, Nana-Ama, Msari, Riyam Al, Schokrpur, Shiruyeh, Pietryga, Ida Franiak, Molinolo, Alfredo A., Mesirov, Jill P., Simon, Aaron B., Fox, Bernard A., Bui, Jack D., Sharabi, Andrew, Cohen, Ezra E. W., Califano, Joseph A., Gutkind, J. Silvio

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The NOTCH4 - HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma von Fukusumi, Takahito, Guo, Theresa W, Sakai, Akihiro, Ando, Mizuo, Ren, Shuling, Haft, Sunny, Liu, Chao, Amornphimoltham, Panomwat, Gutkind, J Silvio, Califano, Joseph A

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Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer von Wang, Zhiyong, Goto, Yusuke, Allevato, Michael M., Wu, Victoria H., Saddawi-Konefka, Robert, Gilardi, Mara, Alvarado, Diego, Yung, Bryan S., O’Farrell, Aoife, Molinolo, Alfredo A., Duvvuri, Umamaheswar, Grandis, Jennifer R., Califano, Joseph A., Cohen, Ezra E. W., Gutkind, J. Silvio

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A novel splice variant of LOXL2 promotes progression of human papillomavirus–negative head and neck squamous cell carcinoma von Liu, Chao, Guo, Theresa, Sakai, Akihiro, Ren, Shuling, Fukusumi, Takahito, Ando, Mizuo, Sadat, Sayed, Saito, Yuki, Califano, Joseph A.

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Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers von Ando, Mizuo, Saito, Yuki, Xu, Guorong, Bui, Nam Q., Medetgul-Ernar, Kate, Pu, Minya, Fisch, Kathleen, Ren, Shuling, Sakai, Akihiro, Fukusumi, Takahito, Liu, Chao, Haft, Sunny, Pang, John, Mark, Adam, Gaykalova, Daria A., Guo, Theresa, Favorov, Alexander V., Yegnasubramanian, Srinivasan, Fertig, Elana J., Ha, Patrick, Tamayo, Pablo, Yamasoba, Tatsuya, Ideker, Trey, Messer, Karen, Califano, Joseph A.

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Elective neck dissection for T3/T4 cN0 sinonasal squamous cell carcinoma von Crawford, Kayva L., Jafari, Aria, Qualliotine, Jesse R., Stuart, Emelia, DeConde, Adam S., Califano, Joseph A., Orosco, Ryan K.

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Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing von Sakai, Akihiro, Ando, Mizuo, Fukusumi, Takahito, Ren, Shuling, Liu, Chao, Qualliotine, Jesse, Haft, Sunny, Sadat, Sayed, Saito, Yuki, Guo, Theresa W., Xu, Guorong, Sasik, Roman, Fisch, Kathleen M., Gutkind, J. Silvio, Fertig, Elana J., Molinolo, Alfredo A., Califano, Joseph A.

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A new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: Creation and rationale for inclusion of tumor (T) characteristics von Farasat, Sharifeh, BS, Yu, Siegrid S., MD, Neel, Victor A., MD, PhD, Nehal, Kishwer S., MD, Lardaro, Thomas, BSc, Mihm, Martin C., MD, Byrd, David R., MD, Balch, Charles M., MD, Califano, Joseph A., MD, Chuang, Alice Y., MD, Sharfman, William H., MD, Shah, Jatin P., MD, PhD, Nghiem, Paul, MD, PhD, Otley, Clark C., MD, Tufaro, Anthony P., DDS, MD, Johnson, Timothy M., MD, Sober, Arthur J., MD, Liégeois, Nanette J., MD, PhD

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Activation of the NOTCH Pathway in Head and Neck Cancer von WENYUE SUN, GAYKALOVA, Daria A, SUN AHN, FERTIG, Elana, SIDRANSKY, David, HOUGHTON, Jeffery, BUDDAVARAPU, Kalyan, SANFORD, Tiffany, CHOUDHARY, Ashish, DARDEN, Will, ADAI, Alex, LATHAM, Gary, OCHS, Michael F, BISHOP, Justin, SHARMA, Rajni, WESTRA, William H, HENNESSEY, Patrick, CHUNG, Christine H, CALIFANO, Joseph A, MAMBO, Elizabeth, ARNAOUTAKIS, Demetri, YAN LIU, LOYO, Myriam, AGRAWAL, Nishant, HOWARD, Jason, RYAN LI

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Trends in incidence and prognosis for head and neck cancer in the United States: A site‐specific analysis of the SEER database von Carvalho, André Lopes, Nishimoto, Inês Nobuko, Califano, Joseph A., Kowalski, Luiz Paulo

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Mutation of chromatin regulators and focal hotspot alterations characterize human papillomavirus–positive oropharyngeal squamous cell carcinoma von Haft, Sunny, Ren, Shuling, Xu, Guorong, Mark, Adam, Fisch, Kathleen, Guo, Theresa W., Khan, Zubair, Pang, John, Ando, Mizuo, Liu, Chao, Sakai, Akihiro, Fukusumi, Takahito, Califano, Joseph A.

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Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway von Miyauchi, Sayuri, Kim, Sangwoo S., Jones, Riley N., Zhang, Lin, Guram, Kripa, Sharma, Sonia, Schoenberger, Stephen P., Cohen, Ezra E.W., Califano, Joseph A., Sharabi, Andrew B.

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