Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia von AGIRRE, Xabier, VILAS-ZORNOZA, Amaia, RIFON, José, BANDRES, Eva, CALASANZ, Maria José, MARTIN, Vanesa, HEINIGER, Anabel, TORRES, Antonio, SIEBERT, Reiner, ROMAN-GOMEZ, José, PROSPER, Felipe, JIMENEZ-VELASCO, Antonio, IGNACIO MARTIN-SUBERO, José, CORDEU, Lucia, GARATE, Leire, SAN JOSE-ENERIZ, Edurne, ABIZANDA, Gloria, RODRIGUEZ-OTERO, Paula, FORTES, Puri

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Prognostic heterogeneity of adult B‐cell precursor acute lymphoblastic leukaemia patients with t(1;19)(q23;p13)/TCF3‐PBX1 treated with measurable residual disease‐oriented protocol... von Ribera, Jordi, Granada, Isabel, Morgades, Mireia, González, Teresa, Ciudad, Juana, Such, Esperanza, Calasanz, María‐José, Mercadal, Santiago, Coll, Rosa, González‐Campos, José, Tormo, Mar, García‐Cadenas, Irene, Gil, Cristina, Cervera, Marta, Barba, Pere, Costa, Dolors, Ayala, Rosa, Bermúdez, Arancha, Orfao, Alberto, Ribera, Josep‐Maria

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Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design von Aguilera-Diaz, Almudena, Vazquez, Iria, Ariceta, Beñat, Mañú, Amagoia, Blasco-Iturri, Zuriñe, Palomino-Echeverría, Sara, Larrayoz, María José, García-Sanz, Ramón, Prieto-Conde, María Isabel, Del Carmen Chillón, María, Alfonso-Pierola, Ana, Prosper, Felipe, Fernandez-Mercado, Marta, Calasanz, María José

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Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth von Agirre, Xabier, Jiménez-Velasco, Antonio, San José-Enériz, Edurne, Garate, Leire, Bandrés, Eva, Cordeu, Lucia, Aparicio, Oscar, Saez, Borja, Navarro, Germán, Vilas-Zornoza, Amaia, Pérez-Roger, Ignacio, García-Foncillas, Jesús, Torres, Antonio, Heiniger, Anabel, Calasanz, María José, Fortes, Puri, Román-Gómez, José, Prósper, Felipe

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Quantification of cyclin D1 and D2 proteins in multiple myeloma identifies different expression patterns from those revealed by gene expression profiling von Cardona-Benavides, Ignacio J, Misiewicz-Krzeminska, Irena, Rojas, Elizabeta A, De Ramón, Cristina, Sanz-Solas, Antonio, Isidro, Isabel, Quwaider, Dalia, López-Guerrero, Aida M, Cuadrado, Myriam, Calasanz, María-José, Rosiñol, Laura, Martínez-López, Joaquín, San Miguel, Jesús F, Mateos, María-Victoria, Corchete, Luis A, Gutiérrez, Norma C

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Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage von Queirós, Ana C., Beekman, Renée, Vilarrasa-Blasi, Roser, Duran-Ferrer, Martí, Clot, Guillem, Merkel, Angelika, Raineri, Emanuele, Russiñol, Nuria, Castellano, Giancarlo, Beà, Sílvia, Navarro, Alba, Kulis, Marta, Verdaguer-Dot, Núria, Jares, Pedro, Enjuanes, Anna, Calasanz, María José, Bergmann, Anke, Vater, Inga, Salaverría, Itziar, van de Werken, Harmen J.G., Wilson, Wyndham H., Datta, Avik, Flicek, Paul, Royo, Romina, Martens, Joost, Giné, Eva, Lopez-Guillermo, Armando, Stunnenberg, Hendrik G., Klapper, Wolfram, Pott, Christiane, Heath, Simon, Gut, Ivo G., Siebert, Reiner, Campo, Elías, Martín-Subero, José I.

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Chromosome banding analysis and genomic microarrays are both useful but not equivalent methods for genomic complexity risk stratification in chronic lymphocytic leukemia patients von Ramos-Campoy, Silvia, Puiggros, Anna, Beà, Sílvia, Bougeon, Sandrine, Larráyoz, María José, Costa, Dolors, Parker, Helen, Rigolin, Gian Matteo, Ortega, Margarita, Blanco, María Laura, Collado, Rosa, Salgado, Rocío, Baumann, Tycho, Gimeno, Eva, Moreno, Carolina, Bosch, Francesc, Calvo, Xavier, Calasanz, María José, Cuneo, Antonio, Strefford, Jonathan C, Nguyen-Khac, Florence, Oscier, David, Haferlach, Claudia, Schoumans, Jacqueline, Espinet, Blanca

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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia von Román-Gómez, José, Cordeu, Lucia, Agirre, Xabier, Jiménez-Velasco, Antonio, San José-Eneriz, Edurne, Garate, Leire, Calasanz, María José, Heiniger, Anabel, Torres, Antonio, Prosper, Felipe

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TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia von Pérez, Cristina, Martínez-Calle, Nicolas, Martín-Subero, José Ignacio, Segura, Victor, Delabesse, Eric, Fernandez-Mercado, Marta, Garate, Leire, Alvarez, Sara, Rifon, José, Varea, Sara, Boultwood, Jacqueline, Wainscoat, James S, Cruz Cigudosa, Juan, Calasanz, María José, Cross, Nicholas C P, Prósper, Felipe, Agirre, Xabier

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DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia von Alvarez, Sara, Suela, Javier, Valencia, Ana, Fernández, Agustín, Wunderlich, Mark, Agirre, Xabier, Prósper, Felipe, Martín-Subero, José Ignacio, Maiques, Alba, Acquadro, Francesco, Rodriguez Perales, Sandra, Calasanz, María José, Roman-Gómez, Jose, Siebert, Reiner, Mulloy, James C, Cervera, José, Sanz, Miguel Angel, Esteller, Manel, Cigudosa, Juan C

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Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) von Akasaka, Takashi, Balasas, Theodore, Russell, Lisa J., Sugimoto, Kei-ji, Majid, Aneela, Walewska, Renata, Karran, E. Loraine, Brown, David G., Cain, Kelvin, Harder, Lana, Gesk, Stefan, Martin-Subero, Jose Ignacio, Atherton, Mark G., Brüggemann, Monika, Calasanz, María José, Davies, Teresa, Haas, Oskar A., Hagemeijer, Anne, Kempski, Helena, Lessard, Michel, Lillington, Debra M., Moore, Sarah, Nguyen-Khac, Florence, Radford-Weiss, Isabelle, Schoch, Claudia, Struski, Stéphanie, Talley, Polly, Welham, Melanie J., Worley, Helen, Strefford, Jon C., Harrison, Christine J., Siebert, Reiner, Dyer, Martin J.S.

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The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia von Bolufer, Pascual, Collado, Maria, Barragan, Eva, Cervera, Jose, Calasanz, Maria-Jose, Colomer, Dolors, Roman-Gomez, Jose, Sanz, Miguel A

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Aberrant DNA methylation profile of chronic and transformed classic Philadelphia-negative myeloproliferative neoplasms von Pérez, Cristina, Pascual, Marien, Martín-Subero, José Ignacio, Bellosillo, Beatriz, Segura, Victor, Delabesse, Eric, Álvarez, Sara, Larrayoz, María José, Rifón, José, Cigudosa, Juan Cruz, Besses, Carles, Calasanz, María José, Cross, Nicholas C P, Prósper, Felipe, Agirre, Xabier

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MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations von San José-Enériz, Edurne, Román-Gómez, José, Jiménez-Velasco, Antonio, Garate, Leire, Martin, Vanesa, Cordeu, Lucia, Vilas-Zornoza, Amaia, Rodríguez-Otero, Paula, Calasanz, María José, Prósper, Felipe, Agirre, Xabier

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NGS-Based Molecular Karyotyping of Multiple Myeloma: Results from the GEM12 Clinical Trial von Rosa-Rosa, Juan Manuel, Cuenca, Isabel, Medina, Alejandro, Vázquez, Iria, Sánchez-delaCruz, Andrea, Buenache, Natalia, Sánchez, Ricardo, Jiménez, Cristina, Rosiñol, Laura, Gutiérrez, Norma C., Ruiz-Heredia, Yanira, Barrio, Santiago, Oriol, Albert, Martin-Ramos, Maria-Luisa, Blanchard, María-Jesús, Ayala, Rosa, Ríos-Tamayo, Rafael, Sureda, Anna, Hernández, Miguel-Teodoro, de la Rubia, Javier, Alkorta-Aranburu, Gorka, Agirre, Xabier, Bladé, Joan, Mateos, María-Victoria, Lahuerta, Juan-José, San-Miguel, Jesús F., Calasanz, María-José, Garcia-Sanz, Ramón, Martínez-Lopez, Joaquín

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Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes von Sole, F, Luno, E, Sanzo, C, Espinet, B, Sanz, GF, Cervera, J, Calasanz, MJ, Cigudosa, JC, Milla, F, Ribera, JM, Bureo, E, Marquez, ML, Arranz, E, Florensa, L

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The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients von Villar, Sara, Ariceta, Beñat, Agirre, Xabier, Urribarri, Aura Daniela, Ayala, Rosa, Martínez-Cuadrón, David, Bergua, Juan Miguel, Vives, Susana, Algarra, Lorenzo, Tormo, Mar, Martínez, Pilar, Serrano, Josefina, Simoes, Catia, Herrera, Pilar, Calasanz, Maria José, Alfonso-Piérola, Ana, Paiva, Bruno, Martínez-López, Joaquín, San Miguel, Jesús F, Prósper, Felipe, Montesinos, Pau

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Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications von Vegliante, Maria Carmela, Royo, Cristina, Palomero, Jara, Salaverria, Itziar, Balint, Balazs, Martín-Guerrero, Idoia, Agirre, Xabier, Lujambio, Amaia, Richter, Julia, Xargay-Torrent, Silvia, Bea, Silvia, Hernandez, Luis, Enjuanes, Anna, Calasanz, María José, Rosenwald, Andreas, Ott, German, Roman-Gomez, José, Prosper, Felipe, Esteller, Manel, Jares, Pedro, Siebert, Reiner, Campo, Elias, Martín-Subero, José I, Amador, Virginia

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Expression profile of Bcl‐2 family proteins in newly diagnosed multiple myeloma patients von De Ramón, Cristina, Rojas, Elizabeta A., Misiewicz‐Krzeminska, Irena, Cardona‐Benavides, Ignacio J., Cuadrado, Myriam, Isidro, Isabel, Calasanz, María‐José, Fernandez, Manuela, García‐Sanz, Ramón, Puig, Noemi, Cedena, M. Teresa, Paiva, Bruno, Rosiñol, Laura, Martínez‐López, Joaquín, Bladé, Joan, Lahuerta, Juan J., San Miguel, Jesús F., Mateos, María V., Corchete, Luis A., Gutiérrez, Norma C.

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Integrated flow cytometry and sequencing to reconstruct evolutionary patterns from dysplasia to acute myeloid leukemia von Simoes, Catia, Chillon, Maria-Carmen, Martínez-Cuadrón, David, Calasanz, Maria-José, Vridiales, María-Belén, Vazquez, Iria, Hernández-Ruano, Montserrat, Ariceta, Beñat, Aguirre-Ruiz, Paula, Burgos, Leire, Alignani, Diego, Sarvide, Sarai, Villar, Sara, Pierola, Ana Alfonso, Prosper, Felipe, Ayala, Rosa, Martínez-López, Joaquin, Bergua Burgues, Juan Miguel, Vives, Susana, Perez-Simon, Jose A., Garcia-Fortes, Maria, Bernal del Castillo, Teresa, Colorado, Mercedes, Olave, Mayte, Rodríguez-Gutiérrez, Juan I., Labrador, Jorge, González, Marcos, San-Miguel, Jesús F., Sanz, Miguel Ángel, Montesinos, Pau, Paiva, Bruno

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