Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets von Galland, Sabine, Vuille, Joanna, Martin, Patricia, Letovanec, Igor, Caignard, Anne, Fregni, Giulia, Stamenkovic, Ivan

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NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment von Frazao, Alexandra, Rethacker, Louise, Messaoudene, Meriem, Avril, Marie-Françoise, Toubert, Antoine, Dulphy, Nicolas, Caignard, Anne

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Editorial: New insights into innate immune cell-based immunotherapies in cancer von Caignard, Anne, Poupot-Marsan, Mary, Lafont, Virginie, Wesch, Daniela, Porta, Chiara

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Immune Infiltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors von RUSAKIEWICZ, Sylvie, SEMERARO, Michaela, CHAIGNEAU, Loic, LE BRUN-LY, Valérie, DUBREUIL, Patrice, CREMER, Isabelle, CAIGNARD, Anne, POIRIER-COLAME, Vichnou, CHABA, Kariman, FLAMENT, Caroline, HALAMA, Niels, JÄGER, Dirk, SARABI, Matthieu, EGGERMONT, Alexander, BONVALOT, Sylvie, COMMO, Frédéric, TERRIER, Philippe, OPOLON, Paule, EMILE, Jean-François, COINDRE, Jean-Michel, KROEMER, Guido, CHAPUT, Nathalie, LE CESNE, Axel, DESBOIS, Mélanie, BLAY, Jean-Yves, ZITVOGEL, Laurence, LOCHER, Clara, MENDEZ, Rosa, VIMOND, Nadège, CONCHA, Angel, GARRIDO, Federico, ISAMBERT, Nicolas

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Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation von Boy, Maxime, Bisio, Valeria, Zhao, Lin-Pierre, Guidez, Fabien, Schell, Bérénice, Lereclus, Emilie, Henry, Guylaine, Villemonteix, Juliette, Rodrigues-Lima, Fernando, Gagne, Katia, Retiere, Christelle, Larcher, Lise, Kim, Rathana, Clappier, Emmanuelle, Sebert, Marie, Mekinian, Arsène, Fain, Olivier, Caignard, Anne, Espeli, Marion, Balabanian, Karl, Toubert, Antoine, Fenaux, Pierre, Ades, Lionel, Dulphy, Nicolas

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Innate lymphoid cells: NK and cytotoxic ILC3 subsets infiltrate metastatic breast cancer lymph nodes von Rethacker, Louise, Boy, Maxime, Bisio, Valeria, Roussin, France, Denizeau, Jordan, Vincent-Salomon, Anne, Borcoman, Edith, Sedlik, Christine, Piaggio, Eliane, Toubert, Antoine, Dulphy, Nicolas, Caignard, Anne

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Phenotypic and Functional Dysregulated Blood NK Cells in Colorectal Cancer Patients Can Be Activated by Cetuximab Plus IL-2 or IL-15 von Rocca, Yamila Sol, Roberti, María Paula, Juliá, Estefanía Paula, Pampena, María Betina, Bruno, Luisina, Rivero, Sergio, Huertas, Eduardo, Sánchez Loria, Fernando, Pairola, Alejandro, Caignard, Anne, Mordoh, José, Levy, Estrella Mariel

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Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma von Jacquelot, Nicolas, Enot, David P, Flament, Caroline, Vimond, Nadège, Blattner, Carolin, Pitt, Jonathan M, Yamazaki, Takahiro, Roberti, María Paula, Daillère, Romain, Vétizou, Marie, Poirier-Colame, Vichnou, Semeraro, Michaëla, Caignard, Anne, Slingluff, Jr, Craig L, Sallusto, Federica, Rusakiewicz, Sylvie, Weide, Benjamin, Marabelle, Aurélien, Kohrt, Holbrook, Dalle, Stéphane, Cavalcanti, Andréa, Kroemer, Guido, Di Giacomo, Anna Maria, Maio, Michele, Wong, Phillip, Yuan, Jianda, Wolchok, Jedd, Umansky, Viktor, Eggermont, Alexander, Zitvogel, Laurence

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Phenotypic and functional characteristics of blood natural killer cells from melanoma patients at different clinical stages von Fregni, Giulia, Messaoudene, Meriem, Fourmentraux-Neves, Emmanuelle, Mazouz-Dorval, Sarra, Chanal, Johan, Maubec, Eve, Marinho, Eduardo, Scheer-Senyarich, Isabelle, Cremer, Isabelle, Avril, Marie-Françoise, Caignard, Anne

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NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs von Borg, Christophe, Jalil, Abdelali, Laderach, Diego, Maruyama, Kouji, Wakasugi, Hiro, Charrier, Sabine, Ryffel, Bernhard, Cambi, Alessandra, Figdor, Carl, Vainchenker, William, Galy, Anne, Caignard, Anne, Zitvogel, Laurence

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TNFR2/BIRC3-TRAF1 signaling pathway as a novel NK cell immune checkpoint in cancer von Ivagnès, Alexandre, Messaoudene, Meriem, Stoll, Gautier, Routy, Bertrand, Fluckiger, Aurélie, Yamazaki, Takahiro, Iribarren, Kristina, Duong, Connie P. M., Fend, Laetitia, Caignard, Anne, Cremer, Isabelle, LeCesne, Axel, Adam, Julien, Honoré, Charles, Mir, Olivier, Chaigneau, Loïc, Berger, Anne, Validire, Pierre, Christidis, Christos, Brun-Ly, Valérie Le, Smyth, Mark J., Mariette, Xavier, Salomon, Benoît L., Kroemer, Guido, Rusakiewicz, Sylvie, Zitvogel, Laurence

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Patient's Natural Killer Cells in the Era of Targeted Therapies: Role for Tumor Killers von Messaoudene, Meriem, Frazao, Alexandra, Gavlovsky, Pierre Jean, Toubert, Antoine, Dulphy, Nicolas, Caignard, Anne

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Serum soluble HLA-E in melanoma: a new potential immune-related marker in cancer von Allard, Mathilde, Oger, Romain, Vignard, Virginie, Percier, Jean-Michel, Fregni, Giulia, Périer, Aurélie, Caignard, Anne, Charreau, Béatrice, Bernardeau, Karine, Khammari, Amir, Dréno, Brigitte, Gervois, Nadine

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Circulating NKp46+ Natural Killer cells have a potential regulatory property and predict distinct survival in Non-Small Cell Lung Cancer von Picard, Emilie, Godet, Yann, Laheurte, Caroline, Dosset, Magalie, Galaine, Jeanne, Beziaud, Laurent, Loyon, Romain, Boullerot, Laura, Lauret Marie Joseph, Elodie, Spehner, Laurie, Jacquin, Marion, Eberst, Guillaume, Gaugler, Béatrice, Le pimpec-Barthes, Françoise, Fabre, Elizabeth, Westeel, Virginie, Caignard, Anne, Borg, Christophe, Adotévi, Olivier

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BRAF inhibitor resistance of melanoma cells triggers increased susceptibility to natural killer cell-mediated lysis von Frazao, Alexandra, Rethacker, Louise, Jeudy, Géraldine, Colombo, Marina, Pasmant, Eric, Avril, Marie-Françoise, Toubert, Antoine, Moins-Teisserenc, Helene, Roelens, Marie, Dalac, Sophie, Maubec, Eve, Caignard, Anne

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Unique Functional Status of Natural Killer Cells in Metastatic Stage IV Melanoma Patients and Its Modulation by Chemotherapy von FREGNI, Giulia, PERIER, Aurélie, PITTARI, Gianfranco, JACOBELLI, Simon, SASTRE, Xavier, GERVOIS, Nadine, ALLARD, Mathilde, BERCOVICI, Nadège, AVRIL, Marie Françoise, CAIGNARD, Anne

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Characterization of the Microenvironment in Positive and Negative Sentinel Lymph Nodes from Melanoma Patients von Messaoudene, Meriem, Périer, Aurélie, Fregni, Giulia, Neves, Emmanuelle, Zitvogel, Laurence, Cremer, Isabelle, Chanal, Johan, Sastre-Garau, Xavier, Deschamps, Lydia, Marinho, Eduardo, Larousserie, Frederique, Maubec, Eve, Avril, Marie-Françoise, Caignard, Anne

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Expression of IL-27 by Tumor Cells in InvasCutaneous and Metastatic Melanomas von Gonin, Julie, Carlotti, Agnès, Dietrich, Céline, Audebourg, Anne, Radenen-Bussière, Brigitte, Caignard, Anne, Avril, Marie-Françoise, Vacher-Lavenu, Marie-Cécile, Larousserie, Frédérique, Devergne, Odile

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Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway von Giron-Michel, Julien, Azzi, Sandy, Khawam, Krystel, Mortier, Erwan, Caignard, Anne, Devocelle, Aurore, Ferrini, Silvano, Croce, Michela, François, Hélène, Lecru, Lola, Charpentier, Bernard, Chouaib, Salem, Azzarone, Bruno, Eid, Pierre

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NK cells sense tumors, course of disease and treatments: Consequences for NK-based therapies von Fregni, Giulia, Perier, Aurélie, Avril, Marie-Françoise, Caignard, Anne

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