T helper 17 cells play a critical pathogenic role in lung cancer von Chang, Seon Hee, Mirabolfathinejad, Seyedeh Golsar, Katta, Harshadadevi, Cumpian, Amber M., Gong, Lei, Caetano, Mauricio S., Moghaddam, Seyed Javad, Dong, Chen

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IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer von Caetano, Mauricio S, Zhang, Huiyuan, Cumpian, Amber M, Gong, Lei, Unver, Nese, Ostrin, Edwin J, Daliri, Soudabeh, Chang, Seon Hee, Ochoa, Cesar E, Hanash, Samir, Behrens, Carmen, Wistuba, Ignacio I, Sternberg, Cinthya, Kadara, Humam, Ferreira, Carlos Gil, Watowich, Stephanie S, Moghaddam, Seyed Javad

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PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling von Ferreira, Luciana Bueno, Palumbo, Antonio, de Mello, Kivvi Duarte, Sternberg, Cinthya, Caetano, Mauricio S, de Oliveira, Felipe Leite, Neves, Adriana Freitas, Nasciutti, Luiz Eurico, Goulart, Luiz Ricardo, Gimba, Etel Rodrigues Pereira

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Low-dose radiation treatment enhances systemic antitumor immune responses by overcoming the inhibitory stroma von Barsoumian, Hampartsoum B, Ramapriyan, Rishab, Younes, Ahmed I, Caetano, Mauricio S, Menon, Hari, Comeaux, Nathan I, Cushman, Taylor R, Schoenhals, Jonathan E, Cadena, Alexandra P, Reilly, Timothy P, Chen, Dawei, Masrorpour, Fatemeh, Li, Ailin, Hong, David S, Diab, Adi, Nguyen, Quynh-Nhu, Glitza, Isabella, Ferrarotto, Renata, Chun, Stephen G, Cortez, Maria Angelica, Welsh, James

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Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase von Gong, Lei, Cumpian, Amber M, Caetano, Mauricio S, Ochoa, Cesar E, De la Garza, Maria Miguelina, Lapid, Daniel J, Mirabolfathinejad, Seyedeh Golsar, Dickey, Burton F, Zhou, Qinghua, Moghaddam, Seyed Javad

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Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer von Caetano, Mauricio S., Hassane, Maya, Van, Hieu T., Bugarin, Emmanuel, Cumpian, Amber M., McDowell, Christina L., Cavazos, Carolina Gonzalez, Zhang, Huiyuan, Deng, Shanshan, Diao, Lixia, Wang, Jing, Evans, Scott E., Behrens, Carmen, Wistuba, Ignacio I., Fuqua, Susan A. W., Lin, Huang, Stabile, Laura P., Watowich, Stephanie S., Kadara, Humam, Moghaddam, Seyed Javad

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Altered cancer metabolism in mechanisms of immunotherapy resistance von Ramapriyan, Rishab, Caetano, Mauricio S., Barsoumian, Hampartsoum B., Mafra, Ana Carolina P., Zambalde, Erika Pereira, Menon, Hari, Tsouko, Efrosini, Welsh, James W., Cortez, Maria Angelica

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Triple Therapy with MerTK and PD1 Inhibition Plus Radiotherapy Promotes Abscopal Antitumor Immune Responses von Caetano, Mauricio S, Younes, Ahmed I, Barsoumian, Hampartsoum B, Quigley, Michael, Menon, Hari, Gao, Chan, Spires, Thomas, Reilly, Timothy P, Cadena, Alexandra P, Cushman, Taylor R, Schoenhals, Jonathan E, Li, Ailin, Nguyen, Quynh-Nhu, Cortez, Maria Angelica, Welsh, James W

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Indoleamine 2,3-dioxygenase 1 inhibition targets anti-PD1-resistant lung tumors by blocking myeloid-derived suppressor cells von Li, Ailin, Barsoumian, Hampartsoum B., Schoenhals, Jonathan E., Cushman, Taylor R., Caetano, Mauricio S., Wang, Xiaohong, Valdecanas, David R., Niknam, Sharareh, Younes, Ahmed I., Li, Guang, Woodward, Wendy A., Cortez, Maria Angelica, Welsh, James W.

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IDO1 Inhibition Overcomes Radiation-Induced “Rebound Immune Suppression” by Reducing Numbers of IDO1-Expressing Myeloid-Derived Suppressor Cells in the Tumor Microenvironment von Li, Ailin, Barsoumian, Hampartsoum B., Schoenhals, Jonathan E., Caetano, Mauricio S., Wang, Xiaohong, Menon, Hari, Valdecanas, David R., Niknam, Sharareh, Younes, Ahmed I., Cortez, Maria Angelica, Welsh, James W.

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Radiation Followed by OX40 Stimulation Drives Local and Abscopal Antitumor Effects in an Anti-PD1-Resistant Lung Tumor Model von Niknam, Sharareh, Barsoumian, Hampartsoum B, Schoenhals, Jonathan E, Jackson, Heather L, Yanamandra, Niranjan, Caetano, Mauricio S, Li, Ailin, Younes, Ahmed I, Cadena, Alexandra, Cushman, Taylor R, Chang, Joe Y, Nguyen, Quynh N, Gomez, Daniel R, Diab, Adi, Heymach, John V, Hwu, Patrick, Cortez, Maria Angelica, Welsh, James W

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Reduced IL‐6 levels and tumor‐associated phospho‐STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo‐inositol von Unver, Nese, Delgado, Oliver, Zeleke, Kirubel, Cumpian, Amber, Tang, Ximing, Caetano, Mauricio S., Wang, Hong, Katayama, Hiroyuki, Yu, Hua, Szabo, Eva, Wistuba, Ignacio I., Moghaddam, Seyed Javad, Hanash, Samir M., Ostrin, Edwin J.

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Overview of ongoing clinical trials investigating combined radiotherapy and immunotherapy von Cushman, Taylor R, Caetano, Mauricio S, Welsh, James W, Verma, Vivek

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Efficient blockade of Akt signaling is a determinant factor to overcome resistance to matuzumab von Meira, Debora D, Almeida, Vitor H, Mororó, Jânio S, Caetano, Mauricio S, Nóbrega, Isabel P, Batista, Delano, Sternberg, Cinthya, Ferreira, Carlos G

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Interplay between estrogen and Stat3/NF-κB-driven immunomodulation in lung cancer von Deng, Shanshan, Ramos-Castaneda, Marco, Velasco, Walter V, Clowers, Michael J, Gutierrez, Berenice A, Noble, Oscar, Dong, Yiping, Zarghooni, Melody, Alvarado, Lucero, Caetano, Mauricio S, Yang, Shuanying, Ostrin, Edwin J, Behrens, Carmen, Wistuba, Ignacio I, Stabile, Laura P, Kadara, Humam, Watowich, Stephanie S, Moghaddam, Seyed Javad

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STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13 von Zhang, Huiyuan, Hu, Hongbo, Greeley, Nathaniel, Jin, Jin, Matthews, Allison J, Ohashi, Erika, Caetano, Mauricio S., Li, Haiyan S., Wu, Xuefeng, Mandal, Pijus K., McMurray, John S., Moghaddam, Seyed Javad, Sun, Shao-Cong, Watowich, Stephanie S.

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IL22 Promotes Kras -Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties von Khosravi, Nasim, Caetano, Mauricio S, Cumpian, Amber M, Unver, Nese, De la Garza Ramos, Cynthia, Noble, Oscar, Daliri, Soudabeh, Hernandez, Belinda J, Gutierrez, Berenice A, Evans, Scott E, Hanash, Samir, Alekseev, Andrei M, Yang, Yi, Chang, Seon Hee, Nurieva, Roza, Kadara, Humam, Chen, Jichao, Ostrin, Edwin J, Moghaddam, Seyed Javad

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COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation von De la Garza, Maria Miguelina, Cumpian, Amber M, Daliri, Soudabeh, Castro-Pando, Susana, Umer, Misha, Gong, Lei, Khosravi, Nasim, Caetano, Mauricio S, Ramos-Castañeda, Marco, Flores, Alejandra Garza, Beltran, Evelyn C, Tran, Hai T, Tuvim, Michael J, Ostrin, Edwin J, Dickey, Burton F, Evans, Christopher M, Moghaddam, Seyed Javad

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Abstract 4398: Impact of Interleukin-22 on K-ras mutant lung tumor microenvironment and stemness properties von Khosravi, Nasim, Cumpian, Amber M., Daliri, Soudabeh, De La Garza, Cynthia, Caetano, Mauricio S., Moghaddam, Seyed Javad

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Impact of interleukin-22 on K-ras mutant lung cancer promotion and stemness properties von Khosravi, Nasim, Cumpian, Amber M., Daliri, Soudabeh, Caetano, Mauricio S., Moghaddam, Seyed Javad

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