Long-term ex situ normothermic perfusion of human split livers for more than 1 week von Lau, Ngee-Soon, Ly, Mark, Dennis, Claude, Jacques, Andrew, Cabanes-Creus, Marti, Toomath, Shamus, Huang, Joanna, Mestrovic, Nicole, Yousif, Paul, Chanda, Sumon, Wang, Chuanmin, Lisowski, Leszek, Liu, Ken, Kench, James G., McCaughan, Geoffrey, Crawford, Michael, Pulitano, Carlo

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Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome von Logan, Grant J, Dane, Allison P, Hallwirth, Claus V, Smyth, Christine M, Wilkie, Emilie E, Amaya, Anais K, Zhu, Erhua, Khandekar, Neeta, Ginn, Samantha L, Liao, Sophia H Y, Cunningham, Sharon C, Sasaki, Natsuki, Cabanes-Creus, Martí, Tam, Patrick P L, Russell, David W, Lisowski, Leszek, Alexander, Ian E

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Adeno-associated virus serotype 2 capsid variants for improved liver-directed gene therapy von Meumann, Nadja, Cabanes-Creus, Marti, Ertelt, Moritz, Navarro, Renina Gale, Lucifora, Julie, Yuan, Qinggong, Nien-Huber, Karin, Abdelrahman, Ahmed, Vu, Xuan-Khang, Zhang, Liang, Franke, Ann-Christin, Schmithals, Christian, Piiper, Albrecht, Vogt, Annabelle, Gonzalez-Carmona, Maria, Frueh, Jochen T, Ullrich, Evelyn, Meuleman, Philip, Talbot, Steven R, Odenthal, Margarete, Ott, Michael, Seifried, Erhard, Schoeder, Clara T, Schwäble, Joachim, Lisowski, Leszek, Büning, Hildegard

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Harnessing whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation von Cabanes-Creus, Marti, Liao, Sophia H. Y., Gale Navarro, Renina, Knight, Maddison, Nazareth, Deborah, Lau, Ngee-Soon, Ly, Mark, Zhu, Erhua, Roca-Pinilla, Ramon, Bugallo Delgado, Ricardo, Vicente, Ana F., Baltazar, Grober, Westhaus, Adrian, Merjane, Jessica, Crawford, Michael, McCaughan, Geoffrey W., Unzu, Carmen, González-Aseguinolaza, Gloria, Alexander, Ian E., Pulitano, Carlo, Lisowski, Leszek

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Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8 von Cabanes-Creus, Marti, Navarro, Renina Gale, Zhu, Erhua, Baltazar, Grober, Liao, Sophia H.Y., Drouyer, Matthieu, Amaya, Anais K., Scott, Suzanne, Nguyen, Loan Hanh, Westhaus, Adrian, Hebben, Matthias, Wilson, Laurence O.W., Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek

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AAVolve: Concatenated long-read deep sequencing enables whole capsid tracking during shuffled AAV library selection von Scott, Suzanne, Westhaus, Adrian, Nazareth, Deborah, Cabanes-Creus, Marti, Navarro, Renina Gale, Chandra, Deborah, Zhu, Erhua, Venkateswaran, Aravind, Alexander, Ian E., Bauer, Denis C., Wilson, Laurence O.W., Lisowski, Leszek

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ADEVO: Proof-of-concept of adenovirus-directed EVOlution by random peptide display on the fiber knob von Sallard, Erwan, Fischer, Julian, Schroeer, Katrin, Dawson, Lisa-Marie, Beaude, Nissai, Affes, Arsalene, Ehrke-Schulz, Eric, Zhang, Wenli, Westhaus, Adrian, Cabanes-Creus, Marti, Lisowski, Leszek, Ruszics, Zsolt, Ehrhardt, Anja

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Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2 von Cabanes-Creus, Marti, Westhaus, Adrian, Navarro, Renina Gale, Baltazar, Grober, Zhu, Erhua, Amaya, Anais K., Liao, Sophia H.Y., Scott, Suzanne, Sallard, Erwan, Dilworth, Kimberley L., Rybicki, Arkadiusz, Drouyer, Matthieu, Hallwirth, Claus V., Bennett, Antonette, Santilli, Giorgia, Thrasher, Adrian J., Agbandje-McKenna, Mavis, Alexander, Ian E., Lisowski, Leszek

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Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes von Kok, Cindy Y., Tsurusaki, Shinya, Cabanes-Creus, Marti, Igoor, Sindhu, Rao, Renuka, Skelton, Rhys, Liao, Sophia H.Y., Ginn, Samantha L., Knight, Maddison, Scott, Suzanne, Mietzsch, Mario, Fitzsimmons, Rebecca, Miller, Jessica, Mohamed, Tamer M.A., McKenna, Robert, Chong, James J.H., Hill, Adam P., Hudson, James E., Alexander, Ian E., Lisowski, Leszek, Kizana, Eddy

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Novel AAV variants with improved tropism for human Schwann cells von Drouyer, Matthieu, Chu, Tak-Ho, Labit, Elodie, Haase, Florencia, Navarro, Renina Gale, Nazareth, Deborah, Rosin, Nicole, Merjane, Jessica, Scott, Suzanne, Cabanes-Creus, Marti, Westhaus, Adrian, Zhu, Erhua, Midha, Rajiv, Alexander, Ian E., Biernaskie, Jeff, Ginn, Samantha L., Lisowski, Leszek

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Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids von Cabanes-Creus, Marti, Navarro, Renina Gale, Liao, Sophia H.Y., Baltazar, Grober, Drouyer, Matthieu, Zhu, Erhua, Scott, Suzanne, Luong, Clement, Wilson, Laurence O.W., Alexander, Ian E., Lisowski, Leszek

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Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution von Cabanes-Creus, Marti, Navarro, Renina Gale, Liao, Sophia H.Y., Scott, Suzanne, Carlessi, Rodrigo, Roca-Pinilla, Ramon, Knight, Maddison, Baltazar, Grober, Zhu, Erhua, Jones, Matthew, Denisenko, Elena, Forrest, Alistair R.R., Alexander, Ian E., Tirnitz-Parker, Janina E.E., Lisowski, Leszek

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Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality von Cabanes-Creus, Marti, Ginn, Samantha L, Amaya, Anais K, Liao, Sophia H Y, Westhaus, Adrian, Hallwirth, Claus V, Wilmott, Patrick, Ward, Jason, Dilworth, Kimberley L, Santilli, Giorgia, Rybicki, Arkadiusz, Nakai, Hiroyuki, Thrasher, Adrian J, Filip, Adrian C, Alexander, Ian E, Lisowski, Leszek

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High-Throughput In Vitro , Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction von Westhaus, Adrian, Cabanes-Creus, Marti, Rybicki, Arkadiusz, Baltazar, Grober, Navarro, Renina Gale, Zhu, Erhua, Drouyer, Matthieu, Knight, Maddison, Albu, Razvan F, Ng, Boaz H, Kalajdzic, Predrag, Kwiatek, Magdalena, Hsu, Kenneth, Santilli, Giorgia, Gold, Wendy, Kramer, Belinda, Gonzalez-Cordero, Anai, Thrasher, Adrian J, Alexander, Ian E, Lisowski, Leszek

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AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression von Westhaus, Adrian, Cabanes-Creus, Marti, Jonker, Timo, Sallard, Erwan, Navarro, Renina Gale, Zhu, Erhua, Baltazar Torres, Grober, Lee, Scott, Wilmott, Patrick, Gonzalez-Cordero, Anai, Santilli, Giorgia, Thrasher, Adrian J, Alexander, Ian E, Lisowski, Leszek

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Liver splitting during normothermic machine perfusion: a novel method to combine the advantages of both in-situ and ex-vivo techniques von Lau, Ngee-Soon, Ly, Mark, Dennis, Claude, Ewenson, Kasper, Ly, Hayden, Huang, Joanna L., Cabanes-Creus, Marti, Chanda, Sumon, Wang, Chuanmin, Lisowski, Leszek, Liu, Ken, Kench, James, McCaughan, Geoffrey, Crawford, Michael, Pulitano, Carlo

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Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors von Westhaus, Adrian, Cabanes-Creus, Marti, Dilworth, Kimberley L, Zhu, Erhua, Salas Gómez, David, Navarro, Renina G, Amaya, Anais K, Scott, Suzanne, Kwiatek, Magdalena, McCorkindale, Alexandra L, Hayman, Tara E, Frahm, Silke, Perocheau, Dany P, Tran, Bang Manh, Vincan, Elizabeth, Wong, Sharon L, Waters, Shafagh A, Riddiough, Georgina E, Perini, Marcos V, Wilson, Laurence O W, Baruteau, Julien, Diecke, Sebastian, González-Aseguinolaza, Gloria, Santilli, Giorgia, Thrasher, Adrian J, Alexander, Ian E, Lisowski, Leszek

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Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors von Westhaus, Adrian, Cabanes Creus, Marti, Dilworth, Kimberley L., Zhu, Erhua, Salas, David, Navarro, Renina Gale, Amaya, Anais Karime, Scott, Suzanne, Kwiatek, Magdalena, McCorkindale, Alexandra L., Hayman, Tara E, Frahm, Silke, Perocheau, Dany, Tran, Bang Manh, Vincan, Elizabeth, Wong, Sharon L, Waters, Shafagh A, Riddiough, Georgina E, Perini, Marcos V, Wilson, Laurence O. W., Baruteau, Julien, Diecke, Sebastian, Gonzalez-Aseguinolaza, Gloria, Santilli, Giorgia, Thrasher, Adrian J., Alexander, Ian Edward, Lisowski, Leszek

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MODIFIED AAV CAPSIDS AND VECTORS von Lisowski, Leszek, Cabanes Creus, Marti

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MODIFIED AAV CAPSIDS AND VECTORS von CABANES CREUS, Marti, LISOWSKI, Leszek

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