Safety, tolerability and pharmacokinetics after single and multiple doses of preladenant (SCH420814) administered in healthy subjects von Cutler, D. L., Tendolkar, A., Grachev, I. D.

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Preladenant, a selective adenosine A2A receptor antagonist, is not associated with QT/QTc prolongation von Wang, Z., Xuan, F., Lin, W. H., Troyer, M. D., Tendolkar, A., Cutler, D. L.

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The Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Ertugliflozin in Subjects With Type 2 Diabetes Mellitus von Sahasrabudhe, V., Terra, S. G., Hickman, A., Saur, D., Shi, H., O'Gorman, M., Zhou, Z., Cutler, D. L.

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Phase I and pharmacological study of the oral farnesyltransferase inhibitor SCH 66336 given once daily to patients with advanced solid tumours von Awada, A., Eskens, F.A.L.M., Piccart, M., Cutler, D.L., van der Gaast, A., Bleiberg, H., Wanders, J., Faber, M.N., Statkevich, P., Fumoleau, P., Verweij, J.

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Phase I and Pharmacokinetic Study of the Oral Farnesyl Transferase Inhibitor SCH 66336 Given Twice Daily to Patients With Advanced Solid Tumors von ESKENS, Ferry A. L. M, AWADA, Ahmad, PICCART, Martine, CUTLER, David L, DE JONGE, Maja J. A, LUYTEN, Gré P. M, FABER, Marije N, STATKEVICH, Paul, SPARREBOOM, Alex, VERWEIJ, Jaap, HANAUSKE, Axel-R

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Oral paclitaxel and HM30181A demonstrate clinical activity in metastatic breast cancer (MBC) patients von Dai, M.-S., Chao, T.-Y., Chao, T.-C., Chiu, C.-F., Lu, Y.-S., Shiah, H.-S., Wu, Y.-Y., Gerald Fetterly, G., Hung, N., Cutler, D.L., Kwan, R., Douglas Kramer, D., Chan, W.-K., Hung, T.

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Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration von Pajkrt, D, Camoglio, L, Tiel-van Buul, MC, de Bruin, K, Cutler, DL, Affrime, MB, Rikken, G, van der Poll, T, ten Cate, JW, van Deventer, SJ

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In vivo effects of interleukin-10 on human cytochrome P450 activity von Gorski, J. Christopher, Hall, Stephen D., Becker, Paula, Affrime, Melton B., Cutler, David L., Haehner‐Daniels, Barbara

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Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers von Huhn, Richard D., Radwanski, Elaine, Gallo, Jose, Affrime, Melton B., Sabo, Ron, Gonyo, Gerilyn, Monge, April, Cutler, David L.

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Pharmacokinetics and Immunomodulatory Properties of Intravenously Administered Recombinant Human Interleukin-10 in Healthy Volunteers von Huhn, Richard D., Radwanski, Elaine, O'Connell, Sean M., Sturgill, Marc G., Clarke, Laura, Cody, Ronald P., Affrime, Melton B., Cutler, David L.

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Population pharmacokinetics of temozolomide in cancer patients von JEN, J. Frank, CUTLER, David L, PAI, Sudhakar M, BATRA, Vijay K, AFFRIME, Melton B, ZAMBAS, Demetris N, HEFT, Samuel, HAJIAN, Gerald

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Pharmacokinetics and leukocyte responses of recombinant human interleukin-10 von RADWANSKI, E, CHAKRABORTY, A, VAN WART, S, HUHN, R. D, CUTLER, D. L, AFFRIME, M. B, JUSKO, W. J

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A Phase I trial of the farnesyl transferase inhibitor SCH66336: evidence for biological and clinical activity von Adjei, A A, Erlichman, C, Davis, J N, Cutler, D L, Sloan, J A, Marks, R S, Hanson, L J, Svingen, P A, Atherton, P, Bishop, W R, Kirschmeier, P, Kaufmann, S H

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Pharmacokinetic and Adrenal Interactions of IL-10 and Prednisone in Healthy Volunteers von Chakraborty, Abhijit, Blum, Robert A., Mis, Suzette M., Cutler, David L., Jusko, William J.

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Disposition of Recombinant Human Interleukin-10 in Subjects with Various Degrees of Renal Function von Andersen, Scott R., Lambrecht, Lawrence J., Swan, Suzanne K., Cutler, David L., Radwanski, Elaine, Affrime, Melton B., Garaud, Jean-Jacques

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Pharmacoimmunodynamic interactions of interleukin-10 and prednisone in healthy volunteers von Chakraborty, Abhijit, Blum, Robert A., Cutler, David L., Jusko, William J.

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Pharmacokinetics of flutamide in patients with renal insufficiency von ANJUM, S, SWAN, S. K, LAMBRECHT, L. J, RADWANSKI, E, CUTLER, D. L, AFFRIME, M. B, HALSTENSON, C. E

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Effect of gastric pH on the relative oral bioavailability and pharmacokinetics of temozolomide von BEALE, P, JUDSON, I, MOORE, S, STATKEVICH, P, MARCO, A, CUTLER, D. L, REIDENBERG, P, BRADA, M

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Clinical, hematologic, and immunologic effects of interleukin-10 in humans von FUCHS, A. C, GRANOWITZ, E. V, CUTLER, D. L, GRINT, P. C, DINARELLO, C. A, SHAPIRO, L, VANNIER, E, LONNEMANN, G, ANGEL, J. B, KENNEDY, J. S, RABSON, A. R, RADWANSKI, E, AFFRIME, M. B

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Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia von PAJKRT, D, VAN DER POLL, T, LEVI, M, CUTLER, D. L, AFFRIME, M. B, VAN DEN ENDE, A, TEN CATE, J. W, VAN DEVENTER, S. J. H

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