Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia von Kühn, Michael W M, Song, Evelyn, Feng, Zhaohui, Sinha, Amit, Chen, Chun-Wei, Deshpande, Aniruddha J, Cusan, Monica, Farnoud, Noushin, Mupo, Annalisa, Grove, Carolyn, Koche, Richard, Bradner, James E, de Stanchina, Elisa, Vassiliou, George S, Hoshii, Takayuki, Armstrong, Scott A

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Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis von Valerio, Daria G, Xu, Haiming, Chen, Chun-Wei, Hoshii, Takayuki, Eisold, Meghan E, Delaney, Christopher, Cusan, Monica, Deshpande, Aniruddha J, Huang, Chun-Hao, Lujambio, Amaia, Zheng, YuJun George, Zuber, Johannes, Pandita, Tej K, Lowe, Scott W, Armstrong, Scott A

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Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia von Ye, Min, Zhang, Hong, Yang, Henry, Koche, Richard, Staber, Philipp B., Cusan, Monica, Levantini, Elena, Welner, Robert S., Bach, Christian S., Zhang, Junyan, Krivtsov, Andrei V., Armstrong, Scott A., Tenen, Daniel G.

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ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells von Redondo Monte, Enric, Wilding, Anja, Leubolt, Georg, Kerbs, Paul, Bagnoli, Johannes W., Hartmann, Luise, Hiddemann, Wolfgang, Chen-Wichmann, Linping, Krebs, Stefan, Blum, Helmut, Cusan, Monica, Vick, Binje, Jeremias, Irmela, Enard, Wolfgang, Theurich, Sebastian, Wichmann, Christian, Greif, Philipp A.

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The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice von Schessl, Christina, Rawat, Vijay P S, Cusan, Monica, Deshpande, Aniruddha, Kohl, Tobias M, Rosten, Patricia M, Spiekermann, Karsten, Humphries, R Keith, Schnittger, Susanne, Kern, Wolfgang, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Bohlander, Stefan K, Feuring-Buske, Michaela, Buske, Christian

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CSF3R T618I Collaborates With RUNX1‐RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition von Swoboda, Anja S., Arfelli, Vanessa C., Danese, Anna, Windisch, Roland, Kerbs, Paul, Redondo Monte, Enric, Bagnoli, Johannes W., Chen‐Wichmann, Linping, Caroleo, Alessandra, Cusan, Monica, Krebs, Stefan, Blum, Helmut, Sterr, Michael, Enard, Wolfgang, Herold, Tobias, Colomé‐Tatché, Maria, Wichmann, Christian, Greif, Philipp A.

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Ectopic Expression of the Homeobox Gene Cdx2 Is the Transforming Event in a Mouse Model of t(12;13)(p13;q12) Acute Myeloid Leukemia von Vijay P. S. Rawat, Cusan, Monica, Deshpande, Aniruddha, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Humphries, R. Keith, Bohlander, Stefan K., Feuring-Buske, Michaela, Buske, Christian

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Inhibition Of LSD1 As a Therapeutic Strategy For The Treatment Of Acute Myeloid Leukemia von Kruger, Ryan G., Mohammad, Helai, Smitheman, Kimberly, Cusan, Monica, Liu, Yan, Pappalardi, Melissa, Federowicz, Kelly, Van Aller, Glenn, Kasparec, Jiri, Tian, Xinrong, Suarez, Dominic, Rouse, Meagan, Schneck, Jessica, Carson, Jeffrey, McDevitt, Patrick, Ho, Thau, McHugh, Charles, Miller, William, Johnson, Neil, Armstrong, Scott A., Tummino, Peter

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ZBTB7A Loss Promotes Synthesis of Lipids and Ketone Bodies in Myeloid Leukemia von Arfelli, Vanessa C., Schmitz, Werner, Kirmaier, Martin E., Redondo Monte, Enric, Kerbs, Paul, Cusan, Monica, Theurich, Sebastian, Wichmann, Christian, Greif, Philipp A.

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LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML von Cusan, Monica, Cai, Sheng F., Mohammad, Helai P., Krivtsov, Andrei, Chramiec, Alan, Loizou, Evangelia, Witkin, Matthew D., Smitheman, Kimberly N., Tenen, Daniel G., Ye, Min, Will, Britta, Steidl, Ulrich, Kruger, Ryan G., Levine, Ross L., Rienhoff, Hugh Y., Koche, Richard P., Armstrong, Scott A.

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Synergistic Antileukemic Effect of Mek and Lsd1 Inhibitors Correlates with Decreased Phospho-Serine 315 of TP53 von Caroleo, Alessandra, Kerbs, Paul, Swoboda, Anja, Wange, Lucas, Heinzlmeir, Stephanie, Chang, Yun-Chien, Küster, Bernhard, Enard, Wolfgang, von Bergwelt, Michael, Greif, Philipp A., Cusan, Monica

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Clinical challenges in prostate cancer management: Metastatic bone-tropism and the role of circulating tumor cells von Guruvayurappan, Gayathri K., Frankenbach-Désor, Tina, Laubach, Markus, Klein, Alexander, von Bergwelt-Baildon, Michael, Cusan, Monica, Aszodi, Attila, Holzapfel, Boris M., Böcker, Wolfgang, Mayer-Wagner, Susanne

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CSF3R T618I Collaborates with RUNX1-RUNX1T1 to Expand Human Haematopoietic Stem and Progenitor Cells von Swoboda, Anja, Windisch, Roland, Kerbs, Paul, Redondo Monte, Enric, Bagnoli, Johannes W., Chen-Wichmann, Linping, Caroleo, Alessandra, Cusan, Monica, Enard, Wolfgang, Herold, Tobias, Wichmann, Christian, Greif, Philipp A.

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GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation von Leubolt, Georg, Tizazu, Belay, Dutta, Sayantanee, Cusan, Monica, Sippenauer, Theresa, Istvanffy, Rouzanna, Oostendorp, Robert A.J., Hiddemann, Wolfgang, Greif, Philipp A.

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GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response von Leubolt, Georg, Redondo Monte, Enric, Wilding, Anja, Kerbs, Paul, Cusan, Monica, Bagnoli, Johannes, Enard, Wolfgang, Hiddemann, Wolfgang, Wichmann, Christian, Schotta, Gunnar, Greif, Philipp A.

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Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation von Redondo Monte, Enric, Leubolt, Georg, Windisch, Roland, Kerbs, Paul, Dutta, Sayantanee, Landspersky, Theresa, Istvánffy, Rouzanna, Oostendorp, Robert A.J., Chen-Wichmann, Linping, Herold, Tobias, Cusan, Monica, Schotta, Gunnar, Wichmann, Christian, Greif, Philipp A.

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Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition von Cai, Sheng F, Chu, S Haihua, Goldberg, Aaron D, Parvin, Salma, Koche, Richard P, Glass, Jacob L, Stein, Eytan M, Tallman, Martin S, Sen, Filiz, Famulare, Christopher A, Cusan, Monica, Huang, Chun-Hao, Chen, Chun-Wei, Zou, Lihua, Cordner, Keith B, DelGaudio, Nicole L, Durani, Vidushi, Kini, Mitali, Rex, Madison, Tian, Helen S, Zuber, Johannes, Baslan, Timour, Lowe, Scott W, Rienhoff, Jr, Hugh Y, Letai, Anthony, Levine, Ross L, Armstrong, Scott A

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Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes von Cusan, Monica, Larkin, Karilyn, Nicolet, Deedra, Jurinovic, Vindi, Mrózek, Krzysztof, Batcha, Aarif M.N., Rothenberg-Thurley, Maja, Schneider, Stephanie, Sauerland, Maria Cristina, Görlich, Dennis, Krug, Utz, Berdel, Wolfgang E., Woermann, Bernhard Josef, Hiddemann, Wolfgang, Braess, Jan, Spiekermann, Karsten, Kohlschmidt, Jessica, Blachly, James S., Mims, Alice S., Walker, Christopher J., Oakes, Christopher C., Orwick, Shelley, Carroll, Andrew J, Blum, William, Powell, Bayard L., Kolitz, Jonathan E, Moore, Joseph O., Mayer, Robert James, Larson, Richard A., Stone, Richard M., Byrd, John C., Metzeler, Klaus H., Herold, Tobias, Eisfeld, Ann-Kathrin

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Leukemia Cell of Origin Influences p53 Activity and Therapeutic Sensitivity Via an Evi1-Dependent Mechanism von Cai, Sheng F, Chu, S Haihua, Goldberg, Aaron D, Parvin, Salma, Koche, Richard, Glass, Jacob L, Stein, Eytan M., Tallman, Martin S., Sen, Filiz, Famulare, Christopher, Cusan, Monica, Huang, Chun-Hao, Chen, Chun-Wei David, Zou, Lihua, Cordner, Keith B, Durani, Vidushi, Kini, Mitali, Rex, Madison, Zuber, Johannes, Baslan, Timour, Lowe, Scott W., Rienhoff, Hugh Young, Levine, Ross L., Armstrong, Scott A.

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LSD1 Inhibition Exerts Its Anti-Leukemic Effect By Recommissioning PU.1- and C/Ebpα-Dependent Enhancers in AML von Cusan, Monica, Cai, Sheng, Mohammad, Helai P, Krivtsov, Andrei V., Chramiec, Alan, Loizou, Evangelia, Tenen, Daniel G., Ye, Min, Will, Britta, Steidl, Ulrich G., Kruger, Ryan G., Koche, Richard, Armstrong, Scott

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