Prediction of N‑Nitrosamine Partition Coefficients for Derisking Drug Substance Manufacturing Processes von Ashworth, Ian W, Curran, Timothy T, Ford, J. Gair, Tomasi, Simone

Volltext

Novel Synthons from Mucochloric Acid:  The First Use of α,β-Dichloro-γ-butenolides and γ-Butyrolactams for Direct Vinylogous Aldol Addition von Das Sarma, Koushik, Zhang, Ji, Curran, Timothy T

Volltext

Development of a Manufacturing Process for an HCV Protease Inhibitor Candidate Molecule von Littler, Benjamin J, Aizenberg, Michael, Ambhaikar, Narendra B, Blythe, Todd A, Curran, Timothy T, Dvornikovs, Vadims, Jung, Young C, Jurkauskas, Valdas, Lee, Elaine C, Looker, Adam R, Luong, Hoa, Martinot, Theodore A, Miller, David B, Neubert-Langille, Bobbianna J, Otten, Pieter A, Rose, Peter J, Ruggiero, Piero L

Volltext

Preparation of .alpha.,.alpha.-difluoro-.beta.-hydroxy esters via a modified Reformatsky reaction von Curran, Timothy T

Volltext

Correction to “Development of a Manufacturing Process for an HCV Protease Inhibitor Candidate Molecule” von Littler, Benjamin J, Aizenberg, Michael, Ambhaikar, Narendra B, Blythe, Todd A, Curran, Timothy T, Dvornikovs, Vadims, Jung, Young C, Jurkauskas, Valdas, Lee, Elaine C, Looker, Adam R, Luong, Hoa, Martinot, Theodore A, Miller, David B, Neubert-Langille, Bobbianna J, Otten, Pieter A, Rose, Peter J, Ruggiero, Piero L

Volltext

The Preparation of Two, Preclinical Amino-quinazolinediones as Antibacterial Agents von Beylin, Vladimir, Boyles, David C, Curran, Timothy T, Macikenas, Dainius, Parlett, Vrieze, Derek

Volltext

Efficient Synthesis of Novel γ-Substituted γ-Butenolides by Lewis Acid Catalyzed Addition of Metal Enolates of Active Methylene Compounds to Mucohalic Acids von Zhang, Ji, Sarma, Koushik Das, Curran, Timothy T, Belmont, Daniel T, Davidson, James G

Volltext

Diels-Alder reactions of 1-aza-1,3-butadienes: room temperature, endo-selective LUMOdiene-controlled [4 + 2] cycloaddition reactions of N-sulfonyl-4-(ethoxycarbonyl)-1-aza-1,3-buta... von Boger, Dale L, Curran, Timothy T

Volltext

Preparation of a HMG-CoA Reductase Inhibitor via an Optimized Imidazole-Forming Condensation Reaction von Bowles, Daniel M, Bolton, Gary L, Boyles, David C, Curran, Timothy T, Hutchings, Richard H, Larsen, Scott D, Miller, Jonathan M, Park, William K. C, Ritsema, Kurtis G, Schineman, David C, Tamm, Markus

Volltext

The preparation of optically active 2-cyclopenten-1,4-diol derivatives from furfuryl alcohol von Curran, Timothy T., Hay, David A., Koegel, Christopher P., Evans, Jonathan C.

Volltext

Electrophilic N-Amination of Two Quinazoline-2,4-diones Using Substituted (Nitrophenyl)hydroxylamines von Boyles, David C, Curran, Timothy T, Parlett, Davis, Mark, Mauro, Frank

Volltext

ChemInform Abstract: Simonis Chromone Synthesis von Curran, Timothy T.

Volltext

ChemInform Abstract: Finnegan Tetrazole Synthesis von Curran, Timothy T.

Volltext

Inverse electron-demand Diels-Alder reactions of N-sulfonyl .alpha.,.beta.-unsaturated imines: a general approach to implementation of the 4.pi. participation of 1-aza-1,3-butadien... von Boger, Dale L, Corbett, Wendy L, Curran, Timothy T, Kasper, A. M

Volltext

Synthesis of the lower subunit of rhizoxin von Boger, Dale L, Curran, Timothy T

Volltext

Lewis and Brönsted acid catalyzed Friedel–Crafts hydroxyalkylation of mucohalic acids: a facile synthesis of functionalized γ-aryl γ-butenolides von Zhang, Ji, Blazecka, Peter G., Curran, Timothy T.

Volltext

Development of the Carbocyclic Nucleoside MDL 201449A:  A Tumor Necrosis Factor-α Inhibitor von Watson, Timothy J. N, Curran, Timothy T, Hay, David A, Shah, Ramnik S, Wenstrup, David L, Webster, Mark E

Volltext

ChemInform Abstract: Recent Progress in the Chemistry of Mucohalic Acids: Versatile Building Blocks in Organic Synthesis von Zhang, Ji, Sarma, Koushik Das, Curran, Timothy T.

Volltext

ChemInform Abstract: Air Oxidation of N-Cyclopropylanilines von Blackburn, Anthony, Bowles, Daniel M., Curran, Timothy T., Kim, Hui

Volltext

Indium (III) mediated Markovnikov addition of malonates and β-ketoesters to terminal alkynes and the formation of Knoevenagel condensation products von Zhang, Ji, Blazecka, Peter G., Angell, Paul, Lovdahl, Mark, Curran, Timothy T.

Volltext