Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity von Siegal, Deborah M, Curnutte, John T, Connolly, Stuart J, Lu, Genmin, Conley, Pamela B, Wiens, Brian L, Mathur, Vandana S, Castillo, Janice, Bronson, Michele D, Leeds, Janet M, Mar, Florie A, Gold, Alex, Crowther, Mark A

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Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model von Lu, Genmin, Pine, Polly, Leeds, Janet M, DeGuzman, Francis, Pratikhya, Pratikhya, Lin, Joyce, Malinowski, John, Hollenbach, Stanley J, Curnutte, John T, Conley, Pamela B

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Novel oral anticoagulants and reversal agents: Considerations for clinical development von Sarich, Troy C., PhD, Seltzer, Jonathan H., MD, Berkowitz, Scott D., MD, Costin', James, MD, Curnutte, John T., MD, Gibson, C. Michael, MD, Hoffman, Maureane, MD, PhD, Kaminskas, Edvardas, MD, Krucoff, Mitchell W., MD, Levy, Jerrold H., MD, Mintz, Paul D., MD, Reilly, Paul A., PhD, Sager, Philip T., MD, Singer, Daniel E., MD, Stockbridge, Norman, MD, PhD, Weitz, Jeffrey I., DM, Kowey, Peter R., MD

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Safety, pharmacokinetics, and reversal of apixaban anticoagulation with andexanet alfa von Siegal, Deborah, Lu, Genmin, Leeds, Janet M., Karbarz, Mark, Castillo, Janice, Mathur, Vandana, Hutchaleelaha, Athiwat, Sinha, Uma, Kitt, Michael, McClure, Matt, Hollenbach, Stanley J., Curnutte, John T., Conley, Pamela B., Crowther, Mark

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Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors von Connolly, Stuart J, Crowther, Mark, Eikelboom, John W, Gibson, C. Michael, Curnutte, John T, Lawrence, John H, Yue, Patrick, Bronson, Michele D, Lu, Genmin, Conley, Pamela B, Verhamme, Peter, Schmidt, Jeannot, Middeldorp, Saskia, Cohen, Alexander T, Beyer-Westendorf, Jan, Albaladejo, Pierre, Lopez-Sendon, Jose, Demchuk, Andrew M, Pallin, Daniel J, Concha, Mauricio, Goodman, Shelly, Leeds, Janet, Souza, Sonia, Siegal, Deborah M, Zotova, Elena, Meeks, Brandi, Ahmad, Sadia, Nakamya, Juliet, Milling, Truman J

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Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors von Connolly, Stuart J, Milling, Truman J, Eikelboom, John W, Gibson, C. Michael, Curnutte, John T, Gold, Alex, Bronson, Michele D, Lu, Genmin, Conley, Pamela B, Verhamme, Peter, Schmidt, Jeannot, Middeldorp, Saskia, Cohen, Alexander T, Beyer-Westendorf, Jan, Albaladejo, Pierre, Lopez-Sendon, Jose, Goodman, Shelly, Leeds, Janet, Wiens, Brian L, Siegal, Deborah M, Zotova, Elena, Meeks, Brandi, Nakamya, Juliet, Lim, W. Ting, Crowther, Mark

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Hemostatic Efficacy and Anti-FXa (Factor Xa) Reversal With Andexanet Alfa in Intracranial Hemorrhage: ANNEXA-4 Substudy von Demchuk, Andrew M., Yue, Patrick, Zotova, Elena, Nakamya, Juliet, Xu, Lizhen, Milling, Truman J., Ohara, Tomoyuki, Goldstein, Joshua N., Middeldorp, Saskia, Verhamme, Peter, Lopez-Sendon, Jose Luis, Conley, Pamela B., Curnutte, John T., Eikelboom, John W., Crowther, Mark, Connolly, Stuart J.

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Complement-Induced Impairment of Innate Immunity During Sepsis von Huber-Lang, Markus S, Younkin, Ellen M, Sarma, J. Vidya, McGuire, Stephanie R, Lu, Kristina T, Guo, Ren Feng, Padgaonkar, Vaishalee A, Curnutte, John T, Erickson, Richard, Ward, Peter A

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Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase von Walder, C E, Green, S P, Darbonne, W C, Mathias, J, Rae, J, Dinauer, M C, Curnutte, J T, Thomas, G R

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Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B-cell Malignancies von Coffey, Greg P, Feng, Jiajia, Betz, Andreas, Pandey, Anjali, Birrell, Matt, Leeds, Janet M, Der, Kenneth, Kadri, Sabah, Lu, Pin, Segal, Jeremy, Wang, Y Lynn, Michelson, Glenn, Curnutte, John T, Conley, Pamela B

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Chronic granulomatous disease von Heyworth, Paul G, Cross, Andrew R, Curnutte, John T

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Andexanet versus prothrombin complex concentrates: Differences in reversal of factor Xa inhibitors in in vitro thrombin generation von Lu, Genmin, Lin, Joyce, Bui, Khanh, Curnutte, John T., Conley, Pamela B.

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Induction of gp91-phox, a Component of the Phagocyte NADPH Oxidase, in Microglial Cells during Central Nervous System Inflammation von Green, Simon P., Cairns, Belinda, Rae, Julie, Errett-Baroncini, Carol, Hongo, Jo-Anne S., Erickson, Richard W., Curnutte, John T.

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Efficacy and safety of the dual SYK/JAK inhibitor cerdulatinib in patients with relapsed or refractory B‐cell malignancies: Results of a phase I study von Hamlin, Paul A., Flinn, Ian W., Wagner‐Johnston, Nina, Burger, Jan A., Coffey, Greg P., Conley, Pamela B., Michelson, Glenn, Leeds, Janet M., Der, Kenneth, Kim, Yvonne, Sabalvaro‐Torres, Alice, Birrell, Matt, Pandey, Anjali, Curnutte, John T., Patel, Manish R.

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Regulation of Phagocyte Oxygen Radical Production by the GTP-Binding Protein Rac 2 von Knaus, Ulla G., Heyworth, Paul G., Evans, Tony, Curnutte, John T., Bokoch, Gary M.

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Focus on FOCIS: The continuing diagnostic challenge of autosomal recessive chronic granulomatous disease von Yu, Grace, Hong, David K, Dionis, Kira Y, Rae, Julie, Heyworth, Paul G, Curnutte, John T, Lewis, David B

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Semi-automatic measurement of intracranial hemorrhage growth on non-contrast CT von Chung, Kevin J, Kuang, Hulin, Federico, Alyssa, Choi, Hyun Seok, Kasickova, Linda, Al Sultan, Abdulaziz Sulaiman, Horn, MacKenzie, Crowther, Mark, Connolly, Stuart J, Yue, Patrick, Curnutte, John T, Demchuk, Andrew M, Menon, Bijoy K, Qiu, Wu

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Pillars article: Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J. Clin. Invest. 1973. 52: 741-744 von Babior, Bernard M, Kipnes, Ruby S, Curnutte, John T

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A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers von Lu, Genmin, Conley, Pamela B., Leeds, Janet M., Karbarz, Mark J., Levy, Gallia G., Mathur, Vandana S., Castillo, Janice, Crowther, Mark, Curnutte, John T.

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Andexanet Alfa Reverses Anticoagulation Effects of Enoxaparin and Associated Bleeding in a Rabbit Acute Hemorrhage Model von Pine, Polly, Lu, Genmin, Canivel, Deogracias, Pratikhya, Pratikhya, DeGuzman, Francis, Karbarz, Mark, Takeda, Kentaro, Malinowski, John, Leeds, Janet M., Curnutte, John T., Conley, Pamela B.

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