Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer von SUN, Jessica D, QIAN LIU, HART, Charles P, JINGLI WANG, AHLUWALIA, Dharmendra, FERRARO, Damien, YAN WANG, DUAN, Jian-Xin, STEVE AMMONS, W, CURD, John G, MATTEUCCI, Mark D

Volltext

TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules von Liu, Qian, Sun, Jessica D., Wang, Jingli, Ahluwalia, Dharmendra, Baker, Amanda F., Cranmer, Lee D., Ferraro, Damien, Wang, Yan, Duan, Jian-Xin, Ammons, W. Steve, Curd, John G., Matteucci, Mark D., Hart, Charles P.

Volltext

High dose calcitriol may reduce thrombosis in cancer patients von Beer, Tomasz M., Venner, Peter M., Ryan, Christopher W., Petrylak, Daniel P., Chatta, Gurkamal, Dean Ruether, J., Chi, Kim N., Curd, John G., DeLoughery, Thomas G.

Volltext

C-reactive Protein as a Prognostic Marker for Men With Androgen-independent Prostate Cancer : Results From the ASCENT Trial von BEER, Tomasz M, LALANI, Alshad S, CHI, Kim N, LEE, Stella, MORI, Motomi, EILERS, Kristine M, CURD, John G, HENNER, W. David, RYAN, Christopher W, VENNER, Peter, RUETHER, J. Dean

Volltext

C‐reactive protein as a prognostic marker for men with androgen‐independent prostate cancer von Beer, Tomasz M., Lalani, Alshad S., Lee, Stella, Mori, Motomi, Eilers, Kristine M., Curd, John G., Henner, W. David, Ryan, Christopher W., Venner, Peter, Ruether, J. Dean, Chi, Kim N.

Volltext

Abstract 5388: Sequence- and regimen-dependent combination therapy with the hypoxia-activated Prodrug TH-302 and Doxorubicin in a preclinical sarcoma xenograft model von Sun, Jessica D., Liu, Qian, Ahluwalia, Dharmendra, Curd, John G., Hart, Charles P.

Volltext

Abstract A42: Antiangiogenic-induced increase in tumor hypoxia in RCC and NSCLC human tumor xenografts and its selective targeting by the hypoxia-activated prodrug TH-302: A model... von Hart, Charles P., Ahluwalia, Dharmendra, Liu, Qian, Meng, Fanying, Bhupathi, Deepthi, Curd, John G., Matteucci, Mark D.

Volltext

Abstract 535: Hypoxia-dependent in vivo activity of the hypoxia-activated prodrug (HAP) TH-302 von Sun, Jessica D., Liu, Qian, Ahluwalia, Dharmendra, Wang, Yan, Meng, Fanying, Bhupathi, Deepthi, Curd, John G., Matteucci, Mark D., Hart, Charles P.

Volltext

Abstract 5054: Hypoxia-activated prodrug TH-302 enhances antitumor activity of antiangiogenics in preclinical models von Sun, Jessica D., Ahluwalia, Dharmendra, Liu, Qian, Wang, Yan, Meng, Fanying, Bhupathi, Deepthi, Curd, John G., Matteucci, Mark D., Hart, Charles P.

Volltext

Abstract A22: Hypoxia-dependent antitumor activity of TH-302, a hypoxia-activated prodrug, in preclinical pancreatic xenograft models von Sun, Jessica D., Liu, Qian, Ahluwalia, Dharmendra, Wang, Yan, Meng, Fanying, Bhupathi, Deepthi, Curd, John G., Matteucci, Mark D., Hart, Charles P.

Volltext

Abstract B185: Bench to bedside experience with TH-302: A tumor-selective hypoxia-activated prodrug as a promising treatment for prostate cancer von Hart, Charles P., Armstrong, Andrew J., Chiorean, Elena G., Sun, Jessica D., Langmuir, Virginia K., Meng, Fanying, Eng, Clarence, Kroll, Stewart, Matteucci, Mark D., Curd, John G.

Volltext

Prekallikrein Activation and High-Molecular-Weight Kininogen Consumption in Hereditary Angioedema von Schapira, Marc, Silver, Lee D, Scott, Cheryl F, Schmaier, Alvin H, Prograis, Lawrence J, Curd, John G, Colman, Robert W

Volltext

Prevalence of Congenital or Acquired Complement Deficiency in Patients with Sporadic Meningococcal Disease von Ellison, Richard T, Kohler, Peter F, Curd, John G, Judson, Franklyn N, Reller, L. Barth

Volltext

Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo : a novel approach to immunosuppressive therapy von CARRERA, C. J, TERAI, C, LOTZ, M, CURD, J. G, PIRO, L. D, BEUTLER, E, CARSON, D. A

Volltext

ADMINISTRATION OF GLUFOSFAMIDE FOR THE TREATMENT OF CANCER von CURD JOHN G

Volltext bestellen

A Novel N-Oxide Drug, AQ4N, Has In Vitro Activity in Lymphoma and Leukemia Cell Lines and Selectively Targets Lymphocytes and Lymphatic Tissues in Vivo von Cleland, Jeffrey L., Wong, Alvin, Alters, Susan E., Harris, Peter A., Dunk, Chris R., Curd, John G., Capizzi, Robert L., Henner, William D.

Volltext

Different patterns of C3 and C4 activation in the varied types of juvenile arthritis von MILLER, J. J, OLDS, L. C, SILVERMAN, E. D, MILGROM, H, CURD, J. G

Volltext

Sjögren's syndrome. Proposed criteria for classification von Fox, Robert I., Robinson, Charles A., Curd, John G., Kozin, Franklin, Howelly, Francis V.

Volltext

Treatment of pemphigus von Grillo-Lopez, Antonio J, Curd, John G

Volltext bestellen

Atlantoaxial lateral mass osteoarthritis. A frequently overlooked cause of severe occipitocervical pain von Star, M J, Curd, J G, Thorne, R P

Volltext