Lipid nanoparticle technology for therapeutic gene regulation in the liver von Witzigmann, Dominik, Kulkarni, Jayesh A., Leung, Jerry, Chen, Sam, Cullis, Pieter R., van der Meel, Roy

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Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency von Cheng, Miffy Hok Yan, Leung, Jerry, Zhang, Yao, Strong, Colton, Basha, Genc, Momeni, Arash, Chen, Yihang, Jan, Eric, Abdolahzadeh, Amir, Wang, Xinying, Kulkarni, Jayesh A., Witzigmann, Dominik, Cullis, Pieter R.

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The cellular mechanisms of neuronal swelling underlying cytotoxic edema von Rungta, Ravi L, Choi, Hyun B, Tyson, John R, Malik, Aqsa, Dissing-Olesen, Lasse, Lin, Paulo J C, Cain, Stuart M, Cullis, Pieter R, Snutch, Terrance P, MacVicar, Brian A

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Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach von Terada, Takeshi, Kulkarni, Jayesh A, Huynh, Ariel, Chen, Sam, van der Meel, Roy, Tam, Yuen Yi C, Cullis, Pieter R

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Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads von Kulkarni, Jayesh A, Witzigmann, Dominik, Leung, Jerry, van der Meel, Roy, Zaifman, Josh, Darjuan, Maria M, Grisch-Chan, Hiu Man, Thöny, Beat, Tam, Yuen Yi C, Cullis, Pieter R

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Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles von Kulkarni, Jayesh A, Thomson, Sarah B, Zaifman, Josh, Leung, Jerry, Wagner, Pamela K, Hill, Austin, Tam, Yuen Yi C, Cullis, Pieter R, Petkau, Terri L, Leavitt, Blair R

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Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core von Leung, Alex K. K, Hafez, Ismail M, Baoukina, Svetlana, Belliveau, Nathan M, Zhigaltsev, Igor V, Afshinmanesh, Elham, Tieleman, D. Peter, Hansen, Carl L, Hope, Michael J, Cullis, Pieter R

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Exciting Times for Lipid Nanoparticles: How Canadian Discoveries Are Enabling Gene Therapies von Cheng, Miffy H. Y., Brimacombe, Cedric A., Verbeke, Rein, Cullis, Pieter R.

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Lipid nanoparticle mRNA systems containing high levels of sphingomyelin engender higher protein expression in hepatic and extra-hepatic tissues von Chander, Nisha, Basha, Genc, Yan Cheng, Miffy Hok, Witzigmann, Dominik, Cullis, Pieter R.

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Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration von Chen, Sam, Tam, Yuen Yi C., Lin, Paulo J.C., Leung, Alex K.K., Tam, Ying K., Cullis, Pieter R.

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Robust Microfluidic Technology and New Lipid Composition for Fabrication of Curcumin-Loaded Liposomes: Effect on the Anticancer Activity and Safety of Cisplatin von Hamano, Nobuhito, Böttger, Roland, Lee, Suen Ern, Yang, Yang, Kulkarni, Jayesh A, Ip, Shell, Cullis, Pieter R, Li, Shyh-Dar

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Lipid Nanoparticle Systems for Enabling Gene Therapies von Cullis, Pieter R., Hope, Michael J.

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Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids von Chen, Sam, Zaifman, Josh, Kulkarni, Jayesh A., Zhigaltsev, Igor V., Tam, Ying K., Ciufolini, Marco A., Tam, Yuen Yi C., Cullis, Pieter R.

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Liposomal drug delivery systems: From concept to clinical applications von Allen, Theresa M., Cullis, Pieter R.

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The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA von Wang, Haitang, Tam, Yuen Yi C, Chen, Sam, Zaifman, Josh, van der Meel, Roy, Ciufolini, Marco A, Cullis, Pieter R

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Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells von Basha, Genc, Novobrantseva, Tatiana I, Rosin, Nicole, Tam, Yuen Yi C, Hafez, Ismail M, Wong, Matthew K, Sugo, Tsukasa, Ruda, Vera M, Qin, June, Klebanov, Boris, Ciufolini, Marco, Akinc, Akin, Tam, Ying K, Hope, Michael J, Cullis, Pieter R

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Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA von Lin, Paulo J.C., PhD, Tam, Yuen Yi C., PhD, Hafez, Ismail, PhD, Sandhu, Ammen, PhD, Chen, Sam, BSc, Ciufolini, Marco A., PhD, Nabi, Ivan R., PhD, Cullis, Pieter R., PhD

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Liposomal Nanomedicines: An Emerging Field von Fenske, David B., Chonn, Arcadio, Cullis, Pieter R.

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Morphological Behavior of Liposomes and Lipid Nanoparticles von Zhigaltsev, Igor V., Cullis, Pieter R.

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Liposome-encapsulated vincristine, vinblastine and vinorelbine: A comparative study of drug loading and retention von Zhigaltsev, Igor V., Maurer, Norbert, Akhong, Quet-Fah, Leone, Robert, Leng, Esther, Wang, Jinfang, Semple, Sean C., Cullis, Pieter R.

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