Conformational Restriction of Flexible Ligands Guided by the Transferred NOE Experiment:  Potent Macrocyclic Inhibitors of Farnesyltransferase von Dinsmore, Christopher J, Bogusky, Michael J, Culberson, J. Christopher, Bergman, Jeffrey M, Homnick, Carl F, Zartman, C. Blair, Mosser, Scott D, Schaber, Michael D, Robinson, Ronald G, Koblan, Kenneth S, Huber, Hans E, Graham, Samuel L, Hartman, George D, Huff, Joel R, Williams, Theresa M

Volltext

Searching in the Plane von Baezayates, R.A., Culberson, J.C., Rawlins, G.J.E.

Volltext

Random Forest:  A Classification and Regression Tool for Compound Classification and QSAR Modeling von Svetnik, Vladimir, Liaw, Andy, Tong, Christopher, Culberson, J. Christopher, Sheridan, Robert P, Feuston, Bradley P

Volltext

Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase von Dinsmore, Christopher J., Williams, Theresa M., O'Neill, Timothy J., Liu, Dongming, Rands, Elaine, Culberson, J.Christopher, Lobell, Robert B., Koblan, Kenneth S., Kohl, Nancy E., Gibbs, Jackson B., Oliff, Allen I., Graham, Samuel L., Hartman, George D.

Volltext

Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase von Ciccarone, Terrence M., MacTough, Suzanne C., Williams, Theresa M., Dinsmore, Christopher J., O'Neill, Timothy J., Shah, Daksha, Culberson, J.Christopher, Koblan, Kenneth S., Kohl, Nancy E., Gibbs, Jackson B., Oliff, Allen I., Graham, Samuel L., Hartman, George D.

Volltext

NMR studies of novel inhibitors bound to farnesyl‐protein transferase von Koblan, Kenneth S., Mosser, Scott D., Omer, Charles A., Christopher Culberson, J., Jane Desolms, S., Giuliani, Elizabeth A., Pitzenberger, Steven M., Bogusky, Michael J.

Volltext

Human Immunodeficiency Virus Type 1 Protease Inhibitors: Evaluation of Resistance Engendered by Amino Acid Substitutions in the Enzyme's Substrate Binding Site von Sardana, Vinod V, Schlabach, Abner J, Graham, Pia, Bush, Bruce L, Condra, Jon H, Culberson, J. Chris, Gotlib, Leah, Graham, Donald J, Kohl, Nancy E

Volltext

Somatotopic organization of single primary afferent axon projections to cat spinal cord dorsal horn von Brown, PB, Gladfelter, WE, Culberson, JC, Covalt-Dunning, D, Sonty, RV, Pubols, LM, Millecchia, RJ

Volltext

Design and Biological Activity of (S)-4-(5-{[1-(3-Chlorobenzyl)-2- oxopyrrolidin-3-ylamino]methyl}imidazol-1-ylmethyl)benzonitrile, a 3-Aminopyrrolidinone Farnesyltransferase Inhib... von Bell, Ian M, Gallicchio, Steven N, Abrams, Marc, Beshore, Douglas C, Buser, Carolyn A, Culberson, J. Christopher, Davide, Joseph, Ellis-Hutchings, Michelle, Fernandes, Christine, Gibbs, Jackson B, Graham, Samuel L, Hartman, George D, Heimbrook, David C, Homnick, Carl F, Huff, Joel R, Kassahun, Kelem, Koblan, Kenneth S, Kohl, Nancy E, Lobell, Robert B, Lynch, Joseph J, Miller, Patricia A, Omer, Charles A, Rodrigues, A. David, Walsh, Eileen S, Williams, Theresa M

Volltext

Structure-based design of HIV-1 protease inhibitors : replacement of two amides and a 10π-aromatic system by a fused bis-tetrahydrofuran von GHOSH, A. K, THOMPSON, W. J, FITZGERALD, P. M. D, CULBERSON, J. C, AXEL, M. G, MCKEE, S. P, HUFF, J. R, ANDERSON, P. S

Volltext

Multicommodity flows in simple multistage networks von Elmallah, E. S., Culberson, J. C.

Volltext

Molecular Transformations as a Way of Finding and Exploiting Consistent Local QSAR von Sheridan, Robert P, Hunt, Peter, Culberson, J. Chris

Volltext

On the Futility of Blind Search: An Algorithmic View of “No Free Lunch” von Culberson, Joseph C.

Volltext

Effect of template secondary structure on the inhibition of HIV-1 reverse transcriptase by a pyridinone non-nucleoside inhibitor von Oisen, David B., Carroll, Steven S., Culberson, J.Chris, Shafer, Jules A., Kuo, Lawrence C.

Volltext

Conformation of a novel tetrapeptide inhibitor NH2-d-Trp-d-Met-Phe(pCl)-Gla-NH2 bound to farnesyl-protein transferase von Bogusky, M.J., Pitzenberger, S.M., Garsky, V.M., Culberson, J.C., Koblan, K.S., Wallace, A., Pessi, A.

Volltext

Comparison of Knowledge-Based and Distance Geometry Approaches for Generation of Molecular Conformations von Feuston, Bradley P, Miller, Michael D, Culberson, J. Christopher, Nachbar, Robert B, Kearsley, Simon K

Volltext

Calculation of molecular electrostatic potentials within the indo framework von Culberson, J.C., Zerner, Michael C.

Volltext

Pattern Databases von Culberson, Joseph C., Schaeffer, Jonathan

Volltext

[24] Development of nonnucleoside HIV reverse transcriptase inhibitors von Tucker, Thomas J., Lumma, William C., Christopher Culberson, J.

Volltext

Dorsal Horn Spatial Representation of Simple Cutaneous Stimuli von Brown, Paul B, Millecchia, Ronald, Lawson, Jeffrey J, Stephens, Stephanie, Harton, Paul, Culberson, James C

Volltext