The dual PI3K/mTOR inhibitor NVP‐BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial‐lysosomal cross‐talk von Seitz, Christian, Hugle, Manuela, Cristofanon, Silvia, Tchoghandjian, Aurélie, Fulda, Simone

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Smac Mimetic Bypasses Apoptosis Resistance in FADD- or Caspase-8-Deficient Cells by Priming for Tumor Necrosis Factor α-Induced Necroptosis von Laukens, Bram, Jennewein, Claudia, Schenk, Barbara, Vanlangenakker, Nele, Schier, Alexander, Cristofanon, Silvia, Zobel, Kerry, Deshayes, Kurt, Vucic, Domagoj, Jeremias, Irmela, Bertrand, Mathieu J.M, Vandenabeele, Peter, Fulda, Simone

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Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network von Signaroldi, Elena, Laise, Pasquale, Cristofanon, Silvia, Brancaccio, Arianna, Reisoli, Elisa, Atashpaz, Sina, Terreni, Maria Rosa, Doglioni, Claudio, Pruneri, Giancarlo, Malatesta, Paolo, Testa, Giuseppe

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Requirement of Nuclear Factor κB for Smac Mimetic–Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis von Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone

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Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275 von Bangert, Annette, Häcker, Sabine, Cristofanon, Silvia, Debatin, Klaus-Michael, Fulda, Simone

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Subapoptogenic Oxidative Stress Strongly Increases the Activity of the Glycolytic Key Enzyme Glyceraldehyde 3-Phosphate Dehydrogenase von Cerella, Claudia, D'Alessio, Maria, Cristofanon, Silvia, De Nicola, Milena, Radogna, Flavia, Dicato, Mario, Diederich, Marc, Ghibelli, Lina

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Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis von UNTERKIRCHER, Thomas, CRISTOFANON, Silvia, KRISHNA VELLANKI, Sri Hari, NONNENMACHER, Lisa, KARPEL-MASSLER, Georg, WIRTZ, Christian Rainer, DEBATIN, Klaus-Michael, FULDA, Simone

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Intracellular Prooxidant Activity of Melatonin Induces a Survival Pathway Involving NF-κB Activation von Cristofanon, Silvia, Uguccioni, Francesco, Cerella, Claudia, Radogna, Flavia, Dicato, Mario, Ghibelli, Lina, Diederich, Marc

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Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2 von Radogna, Flavia, Cristofanon, Silvia, Paternoster, Laura, D'Alessio, Maria, De Nicola, Milena, Cerella, Claudia, Dicato, Mario, Diederich, Marc, Ghibelli, Lina

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NF-κB is required for Smac mimetic-mediated sensitization of glioblastoma cells for γ-irradiation-induced apoptosis von Berger, Rebecca, Jennewein, Claudia, Marschall, Viola, Karl, Sabine, Cristofanon, Silvia, Wagner, Liane, Vellanki, Sri HariKrishna, Hehlgans, Stephanie, Rödel, Franz, Debatin, Klaus-Michael, Ludolph, Albert C, Fulda, Simone

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Tumor necrosis factor α inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulati... von Buck, Isabelle, Morceau, Franck, Cristofanon, Silvia, Heintz, Caroline, Chateauvieux, Sébastien, Reuter, Simone, Dicato, Mario, Diederich, Marc

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Cell cycle arrest in early mitosis and induction of caspase-dependent apoptosis in U937 cells by diallyltetrasulfide (Al2S4) von Cerella, Claudia, Scherer, Christiane, Cristofanon, Silvia, Henry, Estelle, Anwar, Awais, Busch, Corinna, Montenarh, Mathias, Dicato, Mario, Jacob, Claus, Diederich, Marc

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Oxidative, multistep activation of the noncanonical NF-κB pathway via disulfide Bcl-3/p50 complex von Cristofanon, Silvia, Morceau, Franck, Scovassi, A. Ivana, Dicato, Mario, Ghibelli, Lina, Diederich, Marc

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The inhibition of TNF-α-induced NF-κB activation by marine natural products von Folmer, Florence, Jaspars, Marcel, Solano, Godofredo, Cristofanon, Silvia, Henry, Estelle, Tabudravu, Jioji, Black, Kenny, Green, David H., Küpper, Frithjof C., Aalbersberg, William, Feussner, Klaus, Dicato, Mario, Diederich, Marc

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Abstract 2278: Smac mimetic primes FADD- or caspase-8-deficient leukemia cells for TNFα-induced necroptosis and overcomes apoptosis resistance von Schenk, Barbara, Laukens, Bram, Jennewein, Claudia, Vanlangenakker, Nele, Cristofanon, Silvia, Vucic, Domagoj, Jeremias, Irmela, Bertrand, Mathieu, Vandenabeele, Peter, Fulda, Simone

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Tumor necrosis factor α induces γ-glutamyltransferase expression via nuclear factor-κB in cooperation with Sp1 von Reuter, Simone, Schnekenburger, Michael, Cristofanon, Silvia, Buck, Isabelle, Teiten, Marie-Hélène, Daubeuf, Sandrine, Eifes, Serge, Dicato, Mario, Aggarwal, Bharat B., Visvikis, Athanase, Diederich, Marc

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The inhibitory effect of the proinflammatory cytokine TNFα on erythroid differentiation involves erythroid transcription factor modulation von Diederich

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Requirement of Nuclear Factor κB for Smac Mimetic-Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis12 von Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone

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Subapoptogenic Oxidative Stress Strongly Increases the Activity of the Glycolytic Key Enzyme Glyceraldehyde 3‐Phosphate Dehydrogenase: Possible Involvement in an Adaptative Respons... von Cerella, Claudia, D’Alessio, Maria, Cristofanon, Silvia, De Nicola, Milena, Radogna, Flavia, Dicato, Mario, Diederich, Marc, Ghibelli, Lina

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Intracellular Prooxidant Activity of Melatonin Induces a Survival Pathway Involving NF-KB Activation von Cristofanon, Silvia, Uguccioni, Francesco, Cerella, Claudia, Radogna, Flavia, Dicato, Mario, Ghibelli, Lina, Diederich, Marc

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