Interferon-γ: teammate or opponent in the tumour microenvironment? von Gocher, Angela M., Workman, Creg J., Vignali, Dario A. A.

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LAG-3 as the third checkpoint inhibitor von Aggarwal, Vaishali, Workman, Creg J., Vignali, Dario A. A.

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Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment von Scott, Ellen N, Gocher, Angela M, Workman, Creg J, Vignali, Dario A A

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Lymphocyte-activation gene 3 (LAG3): The next immune checkpoint receptor von Ruffo, Elisa, Wu, Richard C., Bruno, Tullia C., Workman, Creg J., Vignali, Dario A.A.

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Targeting regulatory T cells in tumors von Liu, Chang, Workman, Creg J., Vignali, Dario A. A.

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Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity von Jha, Vibha, Workman, Creg J, McGaha, Tracy L, Li, Liping, Vas, Jaya, Vignali, Dario A A, Monestier, Marc

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Adaptive plasticity of IL-10 + and IL-35 + T reg cells cooperatively promotes tumor T cell exhaustion von Sawant, Deepali V, Yano, Hiroshi, Chikina, Maria, Zhang, Qianxia, Liao, Mengting, Liu, Chang, Callahan, Derrick J, Sun, Zhe, Sun, Tao, Tabib, Tracy, Pennathur, Arjun, Corry, David B, Luketich, James D, Lafyatis, Robert, Chen, Wei, Poholek, Amanda C, Bruno, Tullia C, Workman, Creg J, Vignali, Dario A A

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Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy von Andrews, Lawrence P, Cillo, Anthony R, Karapetyan, Lilit, Kirkwood, John M, Workman, Creg J, Vignali, Dario A A

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Intratumoral regulatory T cells: markers, subsets and their impact on anti‐tumor immunity von Yano, Hiroshi, Andrews, Lawrence P., Workman, Creg J., Vignali, Dario A. A.

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Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ von Liu, Chang, Chikina, Maria, Deshpande, Rahul, Menk, Ashley V., Wang, Ting, Tabib, Tracy, Brunazzi, Erin A., Vignali, Kate M., Sun, Ming, Stolz, Donna B., Lafyatis, Robert A., Chen, Wei, Delgoffe, Greg M., Workman, Creg J., Wendell, Stacy G., Vignali, Dario A.A.

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Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion von Sawant, Deepali V., Yano, Hiroshi, Chikina, Maria, Zhang, Qianxia, Liao, Mengting, Liu, Chang, Callahan, Derrick J., Sun, Zhe, Sun, Tao, Tabib, Tracy, Pennathur, Arjun, Corry, David B., Luketich, James D., Lafyatis, Robert, Chen, Wei, Poholek, Amanda C., Bruno, Tullia C., Workman, Creg J., Vignali, Dario A. A.

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The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse von Kataoka, Shunsuke, Manandhar, Priyanka, Lee, Judong, Workman, Creg J, Banerjee, Hridesh, Szymczak-Workman, Andrea L, Kvorjak, Michael, Lohmueller, Jason, Kane, Lawrence P

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Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy von Chuckran, Christopher A, Liu, Chang, Bruno, Tullia C, Workman, Creg J, Vignali, Dario AA

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Therapeutic targeting of regulatory T cells in cancer von Shan, Feng, Somasundaram, Ashwin, Bruno, Tullia C, Workman, Creg J, Vignali, Dario A A

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Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity von Overacre-Delgoffe, Abigail E., Chikina, Maria, Dadey, Rebekah E., Yano, Hiroshi, Brunazzi, Erin A., Shayan, Gulidanna, Horne, William, Moskovitz, Jessica M., Kolls, Jay K., Sander, Cindy, Shuai, Yongli, Normolle, Daniel P., Kirkwood, John M., Ferris, Robert L., Delgoffe, Greg M., Bruno, Tullia C., Workman, Creg J., Vignali, Dario A.A.

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Interleukin-35 Limits Anti-Tumor Immunity von Turnis, Meghan E., Sawant, Deepali V., Szymczak-Workman, Andrea L., Andrews, Lawrence P., Delgoffe, Greg M., Yano, Hiroshi, Beres, Amy J., Vogel, Peter, Workman, Creg J., Vignali, Dario A.A.

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Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis von Delgoffe, Greg M., Woo, Seng-Ryong, Turnis, Meghan E., Gravano, David M., Guy, Cliff, Overacre, Abigail E., Bettini, Matthew L., Vogel, Peter, Finkelstein, David, Bonnevier, Jody, Workman, Creg J., Vignali, Dario A. A.

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IFNγ-induction of TH1-like regulatory T cells controls antiviral responses von Gocher-Demske, Angela M., Cui, Jian, Szymczak-Workman, Andrea L., Vignali, Kate M., Latini, Julianna N., Pieklo, Gwen P., Kimball, Jesse C., Avery, Lyndsay, Cipolla, Ellyse M., Huckestein, Brydie R., Hedden, Lee, Meisel, Marlies, Alcorn, John F., Kane, Lawrence P., Workman, Creg J., Vignali, Dario A. A.

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How regulatory T cells work von Vignali, Dario A. A, Collison, Lauren W, Workman, Creg J

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LAG3 associates with TCR–CD3 complexes and suppresses signaling by driving co-receptor–Lck dissociation von Guy, Clifford, Mitrea, Diana M., Chou, Po-Chien, Temirov, Jamshid, Vignali, Kate M., Liu, Xueyan, Zhang, Hui, Kriwacki, Richard, Bruchez, Marcel P., Watkins, Simon C., Workman, Creg J., Vignali, Dario A. A.

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