Rapid and Selective Cleavage of Amide Groups at Neutral pH: Applications from Hyaluronic Acid to Small Molecules von Jing, Jing, Bankefors, Johan, Bonneaud, Céline, Sawen, Elin, Gerfaud, Thibaud, Westin, Jonatan, El‐Bazbouz, Ghizlane, Kandelin, Lina, Rousseau, Antoine, Olsson, Johan, Karlsson, Anders, Nord, Lars, Bouix‐Peter, Claire, Helander Kenne, Anne, Boiteau, Jean‐Guy, Tomas, Loic, Hennequin, Laurent, Harris, Craig S.

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Novel library synthesis of 3,4-disubstituted pyridin-2(1 H )-ones via cleavage of pyridine-2-oxy-7-azabenzotriazole ethers under ionic hydrogenation conditions at room temperature von Pierre, Romain, Brethon, Anne, Jacques, Sylvain A, Blond, Aurélie, Chambon, Sandrine, Talano, Sandrine, Raffin, Catherine, Musicki, Branislav, Bouix-Peter, Claire, Tomas, Loic, Ouvry, Gilles, Morgentin, Rémy, Hennequin, Laurent F, Harris, Craig S

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Identification of unknown impurities J, RRT 2.2, 2.4, 2.6 and 3.4 in tetralysal® capsules von Billié, Stéphan, Reversé, Kevin, Arlabosse, Jean-Marie, Bertin, Didier, Boulier, Antoine, Cachot, Tony, Chambon, Sandrine, Charras, Karine, Cren, Cécile, Furnes, Bjarte, Gerfaud, Thibaud, Joly-Battaglini, Marine, Longoni, Davide, Mouis, Gregoire, Pierre, Romain, Raynard, Héloïse, Texier, Thomas, Trognon, Caroline, Zanelli, Ugo, Boiteau, Jean-Guy, Harris, Craig S.

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Completion of the impurity profile of lymecycline: Formal identification of impurities E and F von Billié, Stéphan, Reversé, Kevin, Chambon, Sandrine, Cachot, Tony, Pierre, Romain, Gerfaud, Thibaud, Longoni, Davide, Gennari, Massimiliano, Raynard, Héloïse, Talbot, Eric, Charras, Karine, Bertin, Didier, Joly-Battaglini, Marine, Pedrassi, Gerald, Boiteau, Jean-Guy, Cren, Cécile, Harris, Craig S.

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An Efficient Benzoxaborole One‐Pot Synthesis by SiliaCat DPP‐Pd Heterogeneous Catalysis using Diboronic Acid von Kunihiro, Kana, Dumais, Laurence, Lafitte, Guillaume, Varvier, Emeric, Tomas, Loïc, Harris, Craig S.

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Discovery of phenoxyindazoles and phenylthioindazoles as RORγ inverse agonists von Ouvry, Gilles, Bouix-Peter, Claire, Ciesielski, Fabrice, Chantalat, Laurent, Christin, Olivier, Comino, Catherine, Duvert, Denis, Feret, Christophe, Harris, Craig S., Lamy, Laurent, Luzy, Anne-Pascale, Musicki, Branislav, Orfila, Danielle, Pascau, Jonathan, Parnet, Véronique, Perrin, Agnès, Pierre, Romain, Polge, Gaëlle, Raffin, Catherine, Rival, Yves, Taquet, Nathalie, Thoreau, Etienne, Hennequin, Laurent F.

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Novel preparation of chiral α-amino acids using the Mitsunobu-Tsunoda reaction von Noisier, Anaïs F M, Harris, Craig S, Brimble, Margaret A

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New Caspase-1 inhibitor by scaffold hopping into bio-inspired 3D-fragment space von Brethon, Anne, Chantalat, Laurent, Christin, Olivier, Clary, Laurence, Fournier, Jean-François, Gastreich, Marcus, Harris, Craig S., Isabet, Tatiana, Pascau, Jonathan, Thoreau, Etienne, Roche, Didier, Rodeschini, Vincent

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Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis von Boiteau, Jean-Guy, Ouvry, Gilles, Arlabosse, Jean-Marie, Astri, Stéphanie, Beillard, Audrey, Bhurruth-Alcor, Yushma, Bonnary, Laetitia, Bouix-Peter, Claire, Bouquet, Karine, Bourotte, Marilyne, Cardinaud, Isabelle, Comino, Catherine, Deprez, Benoît, Duvert, Denis, Féret, Angélique, Hacini-Rachinel, Feriel, Harris, Craig S., Luzy, Anne-Pascale, Mathieu, Arnaud, Millois, Corinne, Orsini, Nicolas, Pascau, Jonathan, Pinto, Artur, Piwnica, David, Polge, Gaëlle, Reitz, Arnaud, Reversé, Kevin, Rodeville, Nicolas, Rossio, Patricia, Spiesse, Delphine, Tabet, Samuel, Taquet, Nathalie, Tomas, Loïc, Vial, Emmanuel, Hennequin, Laurent F.

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Sulfoximines as potent RORγ inverse agonists von Ouvry, Gilles, Bihl, Franck, Bouix-Peter, Claire, Christin, Olivier, Defoin-Platel, Claire, Deret, Sophie, Feret, Christophe, Froude, David, Hacini-Rachinel, Feriel, Harris, Craig S., Hervouet, Catherine, Lafitte, Guillaume, Luzy, Anne-Pascale, Musicki, Branislav, Orfila, Danielle, Parnet, Veronique, Pascau, Coralie, Pascau, Jonathan, Pierre, Romain, Raffin, Catherine, Rossio, Patricia, Spiesse, Delphine, Taquet, Nathalie, Thoreau, Etienne, Vatinel, Rodolphe, Vial, Emmanuel, Hennequin, Laurent F.

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Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective... von Barlaam, Bernard, Cosulich, Sabina, Delouvrié, Bénédicte, Ellston, Rebecca, Fitzek, Martina, Germain, Hervé, Green, Stephen, Hancox, Urs, Harris, Craig S., Hudson, Kevin, Lambert-van der Brempt, Christine, Lebraud, Honorine, Magnien, Françoise, Lamorlette, Maryannick, Le Griffon, Antoine, Morgentin, Rémy, Ouvry, Gilles, Page, Ken, Pasquet, Georges, Polanska, Urszula, Ruston, Linette, Saleh, Twana, Vautier, Michel, Ward, Lara

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Squaramides as novel class I and IIB histone deacetylase inhibitors for topical treatment of cutaneous t-cell lymphoma von Fournier, Jean-François, Bhurruth-Alcor, Yushma, Musicki, Branislav, Aubert, Jérome, Aurelly, Michèle, Bouix-Peter, Claire, Bouquet, Karinne, Chantalat, Laurent, Delorme, Marion, Drean, Bénédicte, Duvert, Gwenaelle, Fleury-Bregeot, Nicolas, Gauthier, Blanche, Grisendi, Karine, Harris, Craig S., Hennequin, Laurent F., Isabet, Tatiana, Joly, Florence, Lafitte, Guillaume, Millois, Corinne, Morgentin, Rémy, Pascau, Jonathan, Piwnica, David, Rival, Yves, Soulet, Catherine, Thoreau, Étienne, Tomas, Loïc

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Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors von Barlaam, Bernard, Cosulich, Sabina, Fitzek, Martina, Germain, Hervé, Green, Stephen, Hanson, Lyndsey L., Harris, Craig S., Hancox, Urs, Hudson, Kevin, Lambert-van der Brempt, Christine, Lamorlette, Maryannick, Magnien, Françoise, Ouvry, Gilles, Page, Ken, Ruston, Linette, Ward, Lara, Delouvrié, Bénédicte

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Design of selective PI3Kα inhibitors starting from a promiscuous pan kinase scaffold von Barlaam, Bernard, Cosulich, Sabina, Fitzek, Martina, Green, Stephen, Harris, Craig S., Hudson, Kevin, Lambert-van der Brempt, Christine, Ouvry, Gilles, Page, Ken, Ruston, Linette, Ward, Lara, Delouvrié, Bénédicte

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Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors von Ouvry, Gilles, Clary, Laurence, Tomas, Loïc, Aurelly, Michèle, Bonnary, Laetitia, Borde, Emilie, Bouix-Peter, Claire, Chantalat, Laurent, Defoin-Platel, Claire, Deret, Sophie, Forissier, Mathieu, Harris, Craig S, Isabet, Tatiana, Lamy, Laurent, Luzy, Anne-Pascale, Pascau, Jonathan, Soulet, Catherine, Taddei, Alessandro, Taquet, Nathalie, Thoreau, Etienne, Varvier, Emeric, Vial, Emmanuel, Hennequin, Laurent F

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Novel synthesis of C-3-(hetero)aryl [1,2,3]triazolo[1,5-a]pyridines using the Stille reaction von Germain, Hervé, Harris, Craig S., Lebraud, Honorine

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Identification of novel TACE inhibitors compatible with topical application von Ouvry, Gilles, Berton, Yaël, Bhurruth-Alcor, Yushma, Bonnary, Laetitia, Bouix-Peter, Claire, Bouquet, Karine, Bourotte, Marilyne, Chambon, Sandrine, Comino, Catherine, Deprez, Benoît, Duvert, Denis, Duvert, Gwenaëlle, Hacini-Rachinel, Feriel, Harris, Craig S., Luzy, Anne-Pascale, Mathieu, Arnaud, Millois, Corinne, Pascau, Jonathan, Pinto, Artur, Polge, Gaëlle, Reitz, Arnaud, Reversé, Kevin, Rosignoli, Carine, Taquet, Nathalie, Hennequin, Laurent F.

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Diversity-orientated synthesis of 3,5-bis(arylamino)pyrazoles von Degorce, Sébastien, Jung, Frédéric H., Harris, Craig S., Koza, Patrice, Lecoq, Jonathan, Stevenin, Arnaud

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Preparation of 6-aminoquinazolin-4(3H)-ones via direct SNAr on the quinazoline ring von BARLAAM, Bernard, HARRIS, Craig S, LECOQ, Jonathan, HA THI HOANG NGUYEN

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Facile preparation and Suzuki–Miyaura cross-coupling of N-2-alkylated 2H-1,2,3-triazole 4-boronates von Davey, Paul R.J., Delouvrié, Bénédicte, Dorison-Duval, Delphine, Germain, Hervé, Harris, Craig S., Magnien, Françoise, Ouvry, Gilles, Tricotet, Thomas

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