Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes von Henault, Jill, Martinez, Jennifer, Riggs, Jeffrey M., Tian, Jane, Mehta, Payal, Clarke, Lorraine, Sasai, Miwa, Latz, Eicke, Brinkmann, Melanie M., Iwasaki, Akiko, Coyle, Anthony J., Kolbeck, Roland, Green, Douglas R., Sanjuan, Miguel A.

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HMGB1 and RAGE in inflammation and cancer von Sims, Gary P, Rowe, Daniel C, Rietdijk, Svend T, Herbst, Ronald, Coyle, Anthony J

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IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization von Chu, Derek K., BHSc, Llop-Guevara, Alba, BHSc, Walker, Tina D., BSc, Flader, Kristin, BSc, Goncharova, Susanna, MD, PhD, Boudreau, Jeanette E., PhD, Moore, Cheryl Lynn, BSc, In, Tracy Seunghyun, BHSc, Waserman, Susan, MD, MSc, Coyle, Anthony J., PhD, Kolbeck, Roland, PhD, Humbles, Alison A., PhD, Jordana, Manel, MD, PhD

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Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk von Tortola, Luigi, Rosenwald, Esther, Abel, Brian, Blumberg, Hal, Schäfer, Matthias, Coyle, Anthony J, Renauld, Jean-Christoph, Werner, Sabine, Kisielow, Jan, Kopf, Manfred

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IL-9 as a mediator of Th17-driven inflammatory disease von Nowak, Elizabeth C, Weaver, Casey T, Turner, Henrietta, Begum-Haque, Sakhina, Becher, Burkhard, Schreiner, Bettina, Coyle, Anthony J, Kasper, Lloyd H, Noelle, Randolph J

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A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure von Llop-Guevara, Alba, Chu, Derek K, Walker, Tina D, Goncharova, Susanna, Fattouh, Ramzi, Silver, Jonathan S, Moore, Cheryl Lynn, Xie, Juliana L, O'Byrne, Paul M, Coyle, Anthony J, Kolbeck, Roland, Humbles, Alison A, Stämpfli, Martin R, Jordana, Manel

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MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function von Kolbeck, Roland, PhD, Kozhich, Alexander, PhD, Koike, Masamichi, PhD, Peng, Li, PhD, Andersson, Cecilia K., PhD, Damschroder, Melissa M., BA, Reed, Jennifer L., PhD, Woods, Robert, MS, Dall'Acqua, William W., PhD, Stephens, Geoffrey L., PhD, Erjefalt, Jonas S., PhD, Bjermer, Leif, MD, Humbles, Alison A., PhD, Gossage, David, MD, Wu, Herren, PhD, Kiener, Peter A., PhD, Spitalny, George L., PhD, Mackay, Charles R., PhD, Molfino, Nestor A., MD, Coyle, Anthony J., PhD

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Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End Products in Chronic Obstructive Pulmonary Disease von FERHANI, Nassima, LETUVE, Séverine, AUBIER, Michel, PRETOLANI, Marina, KOZHICH, Alexander, THIBAUDEAU, Olivier, GRANDSAIGNE, Martine, MARET, Marielle, DOMBRET, Marie-Christine, SIMS, Gary P, KOLBECK, Roland, COYLE, Anthony J

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Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma von Busse, William W., MD, Katial, Rohit, MD, Gossage, David, MD, MBA, Sari, Suha, PhD, Wang, Bing, PhD, Kolbeck, Roland, PhD, Coyle, Anthony J., PhD, Koike, Masamichi, PhD, Spitalny, George L., PhD, Kiener, Peter A., PhD, Geba, Gregory P., MD, MPH, Molfino, Nestor A., MD

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IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice von Botelho, Fernando M, Bauer, Carla M T, Finch, Donna, Nikota, Jake K, Zavitz, Caleb C J, Kelly, Ashling, Lambert, Kristen N, Piper, Sian, Foster, Martyn L, Goldring, James J P, Wedzicha, Jadwiga A, Bassett, Jennifer, Bramson, Jonathan, Iwakura, Yoichiro, Sleeman, Matthew, Kolbeck, Roland, Coyle, Anthony J, Humbles, Alison A, Stämpfli, Martin R

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE von Coyle, Anthony J, Tian, Jane, Avalos, Ana Maria, Mao, Su-Yau, Chen, Bo, Senthil, Kannaki, Wu, Herren, Parroche, Peggy, Drabic, Stacey, Golenbock, Douglas, Sirois, Cherilyn, Hua, Jing, An, Ling Ling, Audoly, Laurent, La Rosa, Greg, Bierhaus, Angelika, Naworth, Peter, Marshak-Rothstein, Ann, Crow, Mary K, Fitzgerald, Katherine A, Latz, Eicke, Kiener, Peter A

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Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1 von Sutterwala, Fayyaz S., Ogura, Yasunori, Szczepanik, Marian, Lara-Tejero, Maria, Lichtenberger, G. Scott, Grant, Ethan P., Bertin, John, Coyle, Anthony J., Galán, Jorge E., Askenase, Philip W., Flavell, Richard A.

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Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation von Huang, Xuan, Roet, Kasper C.D., Zhang, Liying, Brault, Amy, Berg, Allison P., Jefferson, Anne B., Klug-McLeod, Jackie, Leach, Karen L., Vincent, Fabien, Yang, Hongying, Coyle, Anthony J., Jones, Lyn H., Frost, Devlin, Wiskow, Ole, Chen, Kuchuan, Maeda, Rie, Grantham, Alyssa, Dornon, Mary K., Klim, Joseph R., Siekmann, Marco T., Zhao, Dongyi, Lee, Seungkyu, Eggan, Kevin, Woolf, Clifford J.

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RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA von Sirois, Cherilyn M, Jin, Tengchuan, Miller, Allison L, Bertheloot, Damien, Nakamura, Hirotaka, Horvath, Gabor L, Mian, Abubakar, Jiang, Jiansheng, Schrum, Jacob, Bossaller, Lukas, Pelka, Karin, Garbi, Natalio, Brewah, Yambasu, Tian, Jane, Chang, ChewShun, Chowdhury, Partha S, Sims, Gary P, Kolbeck, Roland, Coyle, Anthony J, Humbles, Alison A, Xiao, T Sam, Latz, Eicke

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Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6 von Sharma, Ankur, Huard, Christine, Vernochet, Cecile, Ziemek, Daniel, Knowlton, Kelly M, Tyminski, Edyta, Paradis, Theresa, Zhang, Ying, Jones, Jessica E C, von Schack, David, Brown, Christopher T, Milos, Patrice M, Coyle, Anthony J, Tremblay, Frederic, Martinez, Robert V

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Characterization of Tiki, a New Family of Wnt-specific Metalloproteases von Zhang, Xinjun, MacDonald, Bryan T., Gao, Huilan, Shamashkin, Michael, Coyle, Anthony J., Martinez, Robert V., He, Xi

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Role of YKL-40 in Bronchial Smooth Muscle Remodeling in Asthma von BARA, Imane, OZIER, Annaig, WOODS, Joanne, DE LARA, Jose-Manuel Tunon, MARTHAN, Roger, BERGER, Patrick, GIRODET, Pierre-Olivier, CARVALHO, Gabrielle, CATTIAUX, Jennifer, BEGUERET, Hugues, THUMEREL, Matthieu, OUSOVA, Olga, KOLBECK, Roland, COYLE, Anthony J

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Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein–Gremlin signaling pathways von Tumelty, Kathleen E., Higginson-Scott, Nathan, Fan, Xueping, Bajaj, Piyush, Knowlton, Kelly M., Shamashkin, Michael, Coyle, Anthony J., Lu, Weining, Berasi, Stephen P.

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A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma von Chupp, Geoffrey L, Lee, Chun Geun, Jarjour, Nizar, Shim, Yun Michael, Holm, Carole T, He, Susan, Dziura, James D, Reed, Jennifer, Coyle, Anthony J, Kiener, Peter, Cullen, Mark, Grandsaigne, Martine, Dombret, Marie-Christine, Aubier, Michel, Pretolani, Marina, Elias, Jack A

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Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis von Lara-Tejero, Maria, Sutterwala, Fayyaz S, Ogura, Yasunori, Grant, Ethan P, Bertin, John, Coyle, Anthony J, Flavell, Richard A, Galán, Jorge E

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