The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response von Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin, Ghazal, Peter

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Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex von Castellano, Brian M., Thelen, Ashley M., Moldavski, Ofer, Feltes, McKenna, van der Welle, Reini E. N., Mydock-McGrane, Laurel, Jiang, Xuntian, van Eijkeren, Robert J, Davis, Oliver B., Louie, Sharon M., Perera, Rushika M., Covey, Douglas F., Nomura, Daniel K., Ory, Daniel S., Zoncu, Roberto

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Multiple functional neurosteroid binding sites on GABAA receptors von Chen, Zi-Wei, Bracamontes, John R, Budelier, Melissa M, Germann, Allison L, Shin, Daniel J, Kathiresan, Krishnan, Qian, Ming-Xing, Manion, Brad, Cheng, Wayland W L, Reichert, David E, Akk, Gustav, Covey, Douglas F, Evers, Alex S

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Fatty acid synthesis configures the plasma membrane for inflammation in diabetes von Wei, Xiaochao, Song, Haowei, Yin, Li, Rizzo, Michael G., Sidhu, Rohini, Covey, Douglas F., Ory, Daniel S., Semenkovich, Clay F.

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Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications von Qian, Mingxing, Xu, Yuanjian, Covey, Douglas F

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A unified total synthesis route to 18-trideuterated and/or 19-trideuterated testosterone, androstenedione and progesterone von Qian, Mingxing, Covey, Douglas F.

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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis von Wang, Xiaobo, Cai, Bishuang, Yang, Xiaoming, Sonubi, Oluwatoni O., Zheng, Ze, Ramakrishnan, Rajasekhar, Shi, Hongxue, Valenti, Luca, Pajvani, Utpal B., Sandhu, Jaspreet, Infante, Rodney E., Radhakrishnan, Arun, Covey, Douglas F., Guan, Kun-Liang, Buck, Jochen, Levin, Lonny R., Tontonoz, Peter, Schwabe, Robert F., Tabas, Ira

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Structural basis of Smoothened regulation by its extracellular domains von Byrne, Eamon F. X., Sircar, Ria, Miller, Paul S., Hedger, George, Luchetti, Giovanni, Nachtergaele, Sigrid, Tully, Mark D., Mydock-McGrane, Laurel, Covey, Douglas F., Rambo, Robert P., Sansom, Mark S. P., Newstead, Simon, Rohatgi, Rajat, Siebold, Christian

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Neurosteroids mediate and modulate the effects of pro-inflammatory stimulation and toll-like receptors on hippocampal plasticity and learning von Izumi, Yukitoshi, O'Dell, Kazuko A, Cashikar, Anil G, Paul, Steven M, Covey, Douglas F, Mennerick, Steven J, Zorumski, Charles F

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A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol von Izumi, Yukitoshi, Cashikar, Anil G, Krishnan, Kathiresan, Paul, Steven M, Covey, Douglas F, Mennerick, Steven J, Zorumski, Charles F

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The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models von Ishikawa, Makoto, Takaseki, Sanae, Yoshitomi, Takeshi, Covey, Douglas F., Zorumski, Charles F., Izumi, Yukitoshi

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Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond von Zorumski, Charles F., Paul, Steven M., Covey, Douglas F., Mennerick, Steven

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Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling von Luchetti, Giovanni, Sircar, Ria, Kong, Jennifer H, Nachtergaele, Sigrid, Sagner, Andreas, Byrne, Eamon Fx, Covey, Douglas F, Siebold, Christian, Rohatgi, Rajat

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5β-Dihydrosteroids: Formation and Properties von Penning, Trevor M, Covey, Douglas F

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Oxysterols are allosteric activators of the oncoprotein Smoothened von Nachtergaele, Sigrid, Mydock, Laurel K, Krishnan, Kathiresan, Rammohan, Jayan, Schlesinger, Paul H, Covey, Douglas F, Rohatgi, Rajat

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Cholesterol accessibility at the ciliary membrane controls hedgehog signaling von Kinnebrew, Maia, Iverson, Ellen J, Patel, Bhaven B, Pusapati, Ganesh V, Kong, Jennifer H, Johnson, Kristen A, Luchetti, Giovanni, Eckert, Kaitlyn M, McDonald, Jeffrey G, Covey, Douglas F, Siebold, Christian, Radhakrishnan, Arun, Rohatgi, Rajat

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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner von Wong, Man Ying, Lewis, Michael, Doherty, James J, Shi, Yang, Cashikar, Anil G, Amelianchik, Anna, Tymchuk, Svitlana, Sullivan, Patrick M, Qian, Mingxing, Covey, Douglas F, Petsko, Gregory A, Holtzman, David M, Paul, Steven M, Luo, Wenjie

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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis von Freitas, Florencio Porto, Alborzinia, Hamed, dos Santos, Ancély Ferreira, Nepachalovich, Palina, Pedrera, Lohans, Zilka, Omkar, Inague, Alex, Klein, Corinna, Aroua, Nesrine, Kaushal, Kamini, Kast, Bettina, Lorenz, Svenja M., Kunz, Viktoria, Nehring, Helene, Xavier da Silva, Thamara N., Chen, Zhiyi, Atici, Sena, Doll, Sebastian G., Schaefer, Emily L., Ekpo, Ifedapo, Schmitz, Werner, Horling, Aline, Imming, Peter, Miyamoto, Sayuri, Wehman, Ann M., Genaro-Mattos, Thiago C., Mirnics, Karoly, Kumar, Lokender, Klein-Seetharaman, Judith, Meierjohann, Svenja, Weigand, Isabel, Kroiss, Matthias, Bornkamm, Georg W., Gomes, Fernando, Netto, Luis Eduardo Soares, Sathian, Manjima B., Konrad, David B., Covey, Douglas F., Michalke, Bernhard, Bommert, Kurt, Bargou, Ralf C., Garcia-Saez, Ana, Pratt, Derek A., Fedorova, Maria, Trumpp, Andreas, Conrad, Marcus, Friedmann Angeli, José Pedro

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Neurosteroids, stress and depression: Potential therapeutic opportunities von ZORUMSKI, Charles F, PAUL, Steven M, IZUMI, Yukitoshi, COVEY, Douglas F, MENNERICK, Steven

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The Structural Basis of Cholesterol Accessibility in Membranes von Olsen, Brett N., Bielska, Agata A., Lee, Tiffany, Daily, Michael D., Covey, Douglas F., Schlesinger, Paul H., Baker, Nathan A., Ory, Daniel S.

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