An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED von Qi, Wei, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Man, Zhang, Jeff, Yu, Zhengtian, Li, Ling, Teng, Lin, Chuai, Shannon, Zhang, Chao, Zhao, Mengxi, Chan, HoMan, Chen, Zijun, Fang, Douglas, Fei, Qi, Feng, Leying, Feng, Lijian, Gao, Yuan, Ge, Hui, Ge, Xinjian, Li, Guobin, Lingel, Andreas, Lin, Ying, Liu, Yueqin, Luo, Fangjun, Shi, Minlong, Wang, Long, Wang, Zhaofu, Yu, Yanyan, Zeng, Jue, Zeng, Chenhui, Zhang, Lijun, Zhang, Qiong, Zhou, Shaolian, Oyang, Counde, Atadja, Peter, Li, En

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Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy von Huang, Ying, Zhang, Jeff, Yu, Zhengtian, Zhang, Hailong, Wang, Youzhen, Lingel, Andreas, Qi, Wei, Gu, Justin, Zhao, Kehao, Shultz, Michael D, Wang, Long, Fu, Xingnian, Sun, Yongfeng, Zhang, Qiong, Jiang, Xiangqing, Zhang, Jiangwei, Zhang, Chunye, Li, Ling, Zeng, Jue, Feng, Lijian, Zhang, Chao, Liu, Yueqin, Zhang, Man, Zhang, Lijun, Zhao, Mengxi, Gao, Zhenting, Liu, Xianghui, Fang, Douglas, Guo, Haibing, Mi, Yuan, Gabriel, Tobias, Dillon, Michael P, Atadja, Peter, Oyang, Counde

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Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies von Huang, Ying, Sendzik, Martin, Zhang, Jeff, Gao, Zhenting, Sun, Yongfeng, Wang, Long, Gu, Justin, Zhao, Kehao, Yu, Zhengtian, Zhang, Lijun, Zhang, Qiong, Blanz, Joachim, Chen, Zijun, Dubost, Valérie, Fang, Douglas, Feng, Lijian, Fu, Xingnian, Kiffe, Michael, Li, Ling, Luo, Fangjun, Luo, Xiao, Mi, Yuan, Mistry, Prakash, Pearson, David, Piaia, Alessandro, Scheufler, Clemens, Terranova, Remi, Weiss, Andreas, Zeng, Jue, Zhang, Hailong, Zhang, Jiangwei, Zhao, Mengxi, Dillon, Michael P, Jeay, Sebastien, Qi, Wei, Moggs, Jonathan, Pissot-Soldermann, Carole, Li, En, Atadja, Peter, Lingel, Andreas, Oyang, Counde

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Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain von Senisterra, Guillermo, Zhu, Hugh Y., Luo, Xiao, Zhang, Hailong, Xun, Guoliang, Lu, Chunliang, Xiao, Wen, Hajian, Taraneh, Loppnau, Peter, Chau, Irene, Li, Fengling, Allali-Hassani, Abdellah, Atadja, Peter, Oyang, Counde, Li, En, Brown, Peter J., Arrowsmith, Cheryl H., Zhao, Kehao, Yu, Zhengtian, Vedadi, Masoud

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Quantitative Profiling of Combinational K27/K36 Modifications on Histone H3 Variants in Mouse Organs von Yu, Yanyan, Chen, Jiajia, Gao, Yuan, Gao, Jun, Liao, Rijing, Wang, Yi, Oyang, Counde, Li, En, Zeng, Chenhui, Zhou, Shaolian, Yang, Pengyuan, Jin, Hong, Yi, Wei

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Absolute Quantification of Histone PTM Marks by MRM-Based LC-MS/MS von Gao, Jun, Liao, Rijing, Yu, Yanyan, Zhai, Huili, Wang, Yingqi, Sack, Ragna, Peters, Antoine H. F. M, Chen, Jiajia, Wu, Haiping, Huang, Zheng, Hu, Min, Qi, Wei, Lu, Chris, Atadja, Peter, Oyang, Counde, Li, En, Yi, Wei, Zhou, Shaolian

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RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists von Bley, Keith R, Bhattacharya, Anindya, Daniels, Don V, Gever, Joel, Jahangir, Alam, O'Yang, Counde, Smith, Steven, Srinivasan, Dinesh, Ford, Anthony P D W, Jett, Mary‐Frances

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Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors von Padilla, Fernando, Bhagirath, Niala, Chen, Shaoqing, Chiao, Eric, Goldstein, David M, Hermann, Johannes C, Hsu, Jonathan, Kennedy-Smith, Joshua J, Kuglstatter, Andreas, Liao, Cheng, Liu, Wenjian, Lowrie, Lee E, Luk, Kin Chun, Lynch, Stephen M, Menke, John, Niu, Linghao, Owens, Timothy D, O-Yang, Counde, Railkar, Aruna, Schoenfeld, Ryan C, Slade, Michelle, Steiner, Sandra, Tan, Yun-Chou, Villaseñor, Armando G, Wang, Ce, Wanner, Jutta, Xie, Wenwei, Xu, Daigen, Zhang, Xiaohu, Zhou, Mingyan, Lucas, Matthew C

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Abstract LB-288: An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED von Qi, Wei, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Man, Zhang, Jeff, Yu, Zhengtian, Li, Ling, Teng, Lin, Chuai, Shannon, Zhang, Chao, Zhao, Mengxi, Chan, HoMan, Chen, Zijun, Fang, Douglas, Qi, Fei, Feng, Leying, Feng, Lijian, Gao, Yuan, Ge, Hui, Ge, Xinjian, Lingel, Andreas, Li, Guobin, Lin, Ying, Liu, Yueqin, Luo, Fangjun, Shi, Minlong, Wang, Long, Wang, Zhaofu, Yu, Yanyan, Zeng, Jue, Zeng, Chenhui, Zhang, Lijun, Zhang, Qiong, Zhou, Shaolian, Oyang, Counde, Atadja, Peter, Li, En

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ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE von O'YANG, Counde, CARTER, David Scott, FORD, Anthony P, CHEN, Wei

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ALPHA 1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE von O'YANG, Counde, CARTER, David Scott, FORD, Anthony P, CHEN, Wei

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α1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE von O'YANG, Counde, CARTER, David Scott, FORD, Anthony P, CHEN, Wei

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ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE von O'Yang, Counde, Chen, Wei, Ford, Anthony P, Carter, David Scott

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ALPHA 1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE von O'YANG, Counde, CARTER, David Scott, FORD, Anthony P, CHEN, Wei

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ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE von O'YANG, Counde, CARTER, David Scott, FORD, Anthony P, CHEN, Wei

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α1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE von O'YANG, Counde, CARTER, David Scott, FORD, Anthony P, CHEN, Wei

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PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS von XIAO, Qitao, WANG, Ce, ZENG, Haiqiang, LIU, Jinbiao, XUN, Guoliang, OYANG, Counde, DENG, Haibing

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PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS von XIAO, Qitao, WANG, Ce, ZENG, Haiqiang, LIU, Jinbiao, XUN, Guoliang, OYANG, Counde, DENG, Haibing

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Synthesis of 4′-cyanothymidine and analogs as potent inhibitors of HIV von O-Yang, Counde, Wu, Helen Y., Fraser-Smith, Elizabeth B., Walker, Keith A.M.

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NUCLEOSIDE-DIPHOSPHATE-HEPTOSE COMPOUNDS FOR TREATING CONDITIONS ASSOCIATED WITH ALPK1 ACTIVITY von LI, Zhihong, O'YANG, Counde, WANG, Hexiang, DU, Nana

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