Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade von D’Alise, Anna Morena, Leoni, Guido, Cotugno, Gabriella, Troise, Fulvia, Langone, Francesca, Fichera, Imma, De Lucia, Maria, Avalle, Lidia, Vitale, Rosa, Leuzzi, Adriano, Bignone, Veronica, Di Matteo, Elena, Tucci, Fabio Giovanni, Poli, Valeria, Lahm, Armin, Catanese, Maria Teresa, Folgori, Antonella, Colloca, Stefano, Nicosia, Alfredo, Scarselli, Elisa

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Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis von Sasso, Emanuele, Froechlich, Guendalina, Cotugno, Gabriella, D’Alise, Anna Morena, Gentile, Chiara, Bignone, Veronica, De Lucia, Maria, Petrovic, Biljana, Campadelli-Fiume, Gabriella, Scarselli, Elisa, Nicosia, Alfredo, Zambrano, Nicola

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Adenovirus Encoded Adjuvant (AdEnA) anti-CTLA-4, a novel strategy to improve Adenovirus based vaccines against infectious diseases and cancer von D'Alise, Anna Morena, Nocchi, Linda, Garzia, Irene, Seclì, Laura, Infante, Luigia, Troise, Fulvia, Cotugno, Gabriella, Allocca, Simona, Romano, Giuseppina, Lahm, Armin, Leoni, Guido, Sasso, Emanuele, Scarselli, Elisa, Nicosia, Alfredo

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Ocular gene therapy: current progress and future prospects von Colella, Pasqualina, Cotugno, Gabriella, Auricchio, Alberto

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Similar therapeutic efficacy between a single administration of gene therapy and multiple administrations of recombinant enzyme in a mouse model of lysosomal storage disease von Ferla, Rita, Claudiani, Pamela, Cotugno, Gabriella, Saccone, Paola, De Leonibus, Elvira, Auricchio, Alberto

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Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment von De Lucia, Maria, Cotugno, Gabriella, Bignone, Veronica, Garzia, Irene, Nocchi, Linda, Langone, Francesca, Petrovic, Biljana, Sasso, Emanuele, Pepe, Simona, Froechlich, Guendalina, Gentile, Chiara, Zambrano, Nicola, Campadelli-Fiume, Gabriella, Nicosia, Alfredo, Scarselli, Elisa, D’Alise, Anna Morena

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Vector Aided Microenvironment programming (VAMP): reprogramming the TME with MVA virus expressing IL-12 for effective antitumor activity von Seclì, Laura, Infante, Luigia, Nocchi, Linda, De Lucia, Maria, Cotugno, Gabriella, Leoni, Guido, Micarelli, Elisa, Garzia, Irene, Avalle, Lidia, Sdruscia, Giulia, Troise, Fulvia, Allocca, Simona, Romano, Giuseppina, Scarselli, Elisa, D'Alise, Anna Morena

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Prime and pull of T cell responses against cancer-exogenous antigens is effective against CPI-resistant tumors von Troise, Fulvia, Leoni, Guido, Sasso, Emanuele, Del Sorbo, Mariarosaria, Esposito, Marialuisa, Romano, Giuseppina, Allocca, Simona, Froechlich, Guendalina, Cotugno, Gabriella, Capone, Stefania, Folgori, Antonella, Scarselli, Elisa, D'Alise, Anna Morena, Nicosia, Alfredo

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Development of a Potency Assay for Nous-209, a Multivalent Neoantigens-Based Genetic Cancer Vaccine von Bartolomeo, Rosa, Troise, Fulvia, Allocca, Simona, Sdruscia, Giulia, Vitale, Rosa, Bignone, Veronica, Petrone, Anna Maria, Romano, Giuseppina, D'Alise, Anna Morena, Ruzza, Valentino, Garzia, Irene, Leoni, Guido, Merone, Rossella, Lanzaro, Francesca, Colloca, Stefano, Siani, Loredana, Scarselli, Elisa, Cotugno, Gabriella

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Gene therapy for mucopolysaccharidosis type VI is effective in cats without pre-existing immunity to AAV8 von Ferla, Rita, O'Malley, Thomas, Calcedo, Roberto, O'Donnell, Patricia, Wang, Ping, Cotugno, Gabriella, Claudiani, Pamela, Wilson, James M, Haskins, Mark, Auricchio, Alberto

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Long-term Amelioration of Feline Mucopolysaccharidosis VI After AAV-mediated Liver Gene Transfer von Cotugno, Gabriella, Annunziata, Patrizia, Tessitore, Alessandra, O'Malley, Thomas, Capalbo, Anita, Faella, Armida, Bartolomeo, Rosa, O'Donnell, Patricia, Wang, Ping, Russo, Fabio, Sleeper, Meg M, Knox, Van W, Fernandez, Steven, Levanduski, Leah, Hopwood, John, De Leonibus, Elvira, Haskins, Mark, Auricchio, Alberto

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VENUS, a Novel Selection Approach to Improve the Accuracy of Neoantigens’ Prediction von Leoni, Guido, D’Alise, Anna Morena, Tucci, Fabio Giovanni, Micarelli, Elisa, Garzia, Irene, De Lucia, Maria, Langone, Francesca, Nocchi, Linda, Cotugno, Gabriella, Bartolomeo, Rosa, Romano, Giuseppina, Allocca, Simona, Troise, Fulvia, Nicosia, Alfredo, Lahm, Armin, Scarselli, Elisa

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Impact of age at administration, lysosomal storage, and transgene regulatory elements on AAV2/8-mediated rat liver transduction von Cotugno, Gabriella, Annunziata, Patrizia, Barone, Maria Vittoria, Karali, Marianthi, Banfi, Sandro, Auricchio, Alberto

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1526 Nous-209 genetic vaccine encoding shared cancer neoantigens is safe and elicits robust immune response in healthy Lynch syndrome carriers: interim results from Phase 1 cancer... von D’Alise, Morena, Willis, Jason, Leoni, Guido, Cruz-Correa, Marcia, Hall, Michael J, Idos, Gregory E, Garzia, Irene, Antonucci, Laura, Cotugno, Gabriella, Siani, Loredana, Gogov, Sven, Liu, Diane, Lee, Jack, Vornik, Lana A, Uribe, Laura Reyes, Garcia-Gonzalez, Araceli, Richmond, Ellen, Umar, Asad, Brown, Powel H, Rodriguez, Luz Maria, Scarselli, Elisa, Vilar, Eduardo

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Maximizing cancer therapy via complementary mechanisms of immune activation: PD-1 blockade, neoantigen vaccination, and Tregs depletion von D'Alise, Anna Morena, Leoni, Guido, De Lucia, Maria, Langone, Francesca, Nocchi, Linda, Tucci, Fabio Giovanni, Micarelli, Elisa, Cotugno, Gabriella, Troise, Fulvia, Garzia, Irene, Vitale, Rosa, Bignone, Veronica, Di Matteo, Elena, Bartolomeo, Rosa, Charych, Deborah H, Lahm, Armin, Zalevsky, Jonathan, Nicosia, Alfredo, Scarselli, Elisa

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Inhibition of ocular neovascularization by hedgehog blockade von Surace, Enrico M, Balaggan, Kamaljit S, Tessitore, Alessandra, Mussolino, Claudio, Cotugno, Gabriella, Bonetti, Ciro, Vitale, Aniello, Ali, Robin R, Auricchio, Alberto

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Personalized Cancer Vaccines Go Viral: Viral Vectors in the Era of Personalized Immunotherapy of Cancer von Seclì, Laura, Leoni, Guido, Ruzza, Valentino, Siani, Loredana, Cotugno, Gabriella, Scarselli, Elisa, D'Alise, Anna Morena

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A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability von Leoni, Guido, D'Alise, Anna Morena, Cotugno, Gabriella, Langone, Francesca, Garzia, Irene, De Lucia, Maria, Fichera, Imma, Vitale, Rosa, Bignone, Veronica, Tucci, Fabio Giovanni, Mori, Federica, Leuzzi, Adriano, Di Matteo, Elena, Troise, Fulvia, Abbate, Adele, Merone, Rossella, Ruzza, Valentino, Diodoro, Maria Grazia, Yadav, Mahesh, Gordon-Alonso, Monica, Vanhaver, Cristophe, Panigada, Maddalena, Soprana, Elisa, Siccardi, Antonio, Folgori, Antonella, Colloca, Stefano, van der Bruggen, Pierre, Nicosia, Alfredo, Lahm, Armin, Catanese, Maria Teresa, Scarselli, Elisa

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Phase I trial of viral vector based personalized vaccination elicits robust neoantigen specific antitumor T cell responses von D'Alise, Anna Morena, Leoni, Guido, Cotugno, Gabriella, Siani, Loredana, Vitale, Rosa, Ruzza, Valentino, Garzia, Irene, Antonucci, Laura, Micarelli, Elisa, Venafra, Veronica, Gogov, Sven, Capone, Alessia, Runswick, Sarah, Martin-Liberal, Juan, Calvo, Emiliano, Moreno, Victor, Symeonides, Stefan N, Scarselli, Elisa, Bechter, Oliver

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Generation of a Retargeted Oncolytic Herpes Virus Encoding Adenosine Deaminase for Tumor Adenosine Clearance von Gentile, Chiara, Finizio, Arianna, Froechlich, Guendalina, D'Alise, Anna Morena, Cotugno, Gabriella, Amiranda, Sara, Nicosia, Alfredo, Scarselli, Elisa, Zambrano, Nicola, Sasso, Emanuele

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