A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder Cancer von Goodspeed, Andrew, Jean, Annie, Costello, James C.

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Biologically Informed Neural Networks Predict Drug Responses von Greene, Casey S., Costello, James C.

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Next-Generation Machine Learning for Biological Networks von Camacho, Diogo M., Collins, Katherine M., Powers, Rani K., Costello, James C., Collins, James J.

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Community mining of open clinical trial data von Laajala, Teemu D, Guinney, Justin, Costello, James C

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Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics von Goodspeed, Andrew, Heiser, Laura M, Gray, Joe W, Costello, James C

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Improved inference of chromosome conformation from images of labeled loci [version 3; peer review: 2 approved] von Ross, Brian C, Costello, James C

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Improved inference of chromosome conformation from images of labeled loci [version 2; peer review: 1 approved, 1 approved with reservations] von Ross, Brian C, Costello, James C

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Crowdsourcing biomedical research: leveraging communities as innovation engines von Saez-Rodriguez, Julio, Costello, James C., Friend, Stephen H., Kellen, Michael R., Mangravite, Lara, Meyer, Pablo, Norman, Thea, Stolovitzky, Gustavo

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Metastatic cells are preferentially vulnerable to lysosomal inhibition von Morgan, Michael J., Fitzwalter, Brent E., Owens, Charles R., Powers, Rani K., Sottnik, Joseph L., Gamez, Graciela, Costello, James C., Theodorescu, Dan, Thorburn, Andrew

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Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes von Stern, Josh Lewis, Paucek, Richard D., Huang, Franklin W., Ghandi, Mahmoud, Nwumeh, Ronald, Costello, James C., Cech, Thomas R.

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Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy von Tu, Megan M., Abdel-Hafiz, Hany A., Jones, Robert T., Jean, Annie, Hoff, Katelyn J., Duex, Jason E., Chauca-Diaz, Ana, Costello, James C., Dancik, Garrett M., Tamburini, Beth A. Jirón, Czerniak, Bogdan, Kaye, Jonathan, Theodorescu, Dan

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ProstaMine: a bioinformatics tool for identifying subtype-specific co-alterations associated with aggressiveness in prostate cancer von Orman, Michael V, Sreekanth, Varsha, Laajala, Teemu D, Cramer, Scott D, Costello, James C

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Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression von Wang, Chu-An, Drasin, David, Pham, Catherine, Jedlicka, Paul, Zaberezhnyy, Vadym, Guney, Michelle, Li, Howard, Nemenoff, Raphael, Costello, James C, Tan, Aik-Choon, Ford, Heide L

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Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth von Tarca, Adi L., Pataki, Bálint Ármin, Romero, Roberto, Sirota, Marina, Guan, Yuanfang, Kutum, Rintu, Gomez-Lopez, Nardhy, Done, Bogdan, Bhatti, Gaurav, Yu, Thomas, Andreoletti, Gaia, Chaiworapongsa, Tinnakorn, Hassan, Sonia S., Hsu, Chaur-Dong, Aghaeepour, Nima, Stolovitzky, Gustavo, Csabai, Istvan, Costello, James C.

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SOPHIE: Generative Neural Networks Separate Common and Specific Transcriptional Responses von Lee, Alexandra J., Mould, Dallas L., Crawford, Jake, Hu, Dongbo, Powers, Rani K., Doing, Georgia, Costello, James C., Hogan, Deborah A., Greene, Casey S.

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A harmonized resource of integrated prostate cancer clinical, -omic, and signature features von Laajala, Teemu D., Sreekanth, Varsha, Soupir, Alex C., Creed, Jordan H., Halkola, Anni S., Calboli, Federico C. F., Singaravelu, Kalaimathy, Orman, Michael V., Colin-Leitzinger, Christelle, Gerke, Travis, Fridley, Brooke L., Tyekucheva, Svitlana, Costello, James C.

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Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection von Thomas, Samantha N., Niemeyer, Brian F., Jimenez-Valdes, Rocio J., Kaiser, Alexander J., Espinosa, Joaquin M., Sullivan, Kelly D., Goodspeed, Andrew, Costello, James C., Alder, Jonathan K., Cañas-Arranz, Rodrigo, García-Sastre, Adolfo, Benam, Kambez H.

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Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia von Pei, Shanshan, Pollyea, Daniel A., Gustafson, Annika, Stevens, Brett M., Minhajuddin, Mohammad, Fu, Rui, Riemondy, Kent A., Gillen, Austin E., Sheridan, Ryan M., Kim, Jihye, Costello, James C., Amaya, Maria L., Inguva, Anagha, Winters, Amanda, Ye, Haobin, Krug, Anna, Jones, Courtney L., Adane, Biniam, Khan, Nabilah, Ponder, Jessica, Schowinsky, Jeffrey, Abbott, Diana, Hammes, Andrew, Myers, Jason R., Ashton, John M., Nemkov, Travis, D'Alessandro, Angelo, Gutman, Jonathan A., Ramsey, Haley E., Savona, Michael R., Smith, Clayton A., Jordan, Craig T.

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Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma von Kwong, Lawrence N, Costello, James C, Liu, Huiyun, Jiang, Shan, Helms, Timothy L, Langsdorf, Aliete E, Jakubosky, David, Genovese, Giannicola, Muller, Florian L, Jeong, Joseph H, Bender, Ryan P, Chu, Gerald C, Flaherty, Keith T, Wargo, Jennifer A, Collins, James J, Chin, Lynda

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PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation von Shull, Lomeli C, Lencer, Ezra S, Kim, Hyun Min, Goyama, Susumu, Kurokawa, Mineo, Costello, James C, Jones, Kenneth, Artinger, Kristin B

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