Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma von Harrington, Bonnie K, Gardner, Heather L, Izumi, Raquel, Hamdy, Ahmed, Rothbaum, Wayne, Coombes, Kevin R, Covey, Todd, Kaptein, Allard, Gulrajani, Michael, Van Lith, Bart, Krejsa, Cecile, Coss, Christopher C, Russell, Duncan S, Zhang, Xiaoli, Urie, Bridget K, London, Cheryl A, Byrd, John C, Johnson, Amy J, Kisseberth, William C

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Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer von Ponnusamy, Suriyan, Coss, Christopher C, Thiyagarajan, Thirumagal, Watts, Kate, Hwang, Dong-Jin, He, Yali, Selth, Luke A, McEwan, Iain J, Duke, Charles B, Pagadala, Jayaprakash, Singh, Geetika, Wake, Robert W, Ledbetter, Christopher, Tilley, Wayne D, Moldoveanu, Tudor, Dalton, James T, Miller, Duane D, Narayanan, Ramesh

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Discovery of Anticancer Agents of Diverse Natural Origin von Aldrich, Leslie N, Burdette, Joanna E, Carcache de Blanco, Esperanza, Coss, Christopher C, Eustaquio, Alessandra S, Fuchs, James R, Kinghorn, A. Douglas, MacFarlane, Amanda, Mize, Brittney K, Oberlies, Nicholas H, Orjala, Jimmy, Pearce, Cedric J, Phelps, Mitch A, Rakotondraibe, Liva Harinantenaina, Ren, Yulin, Soejarto, Djaja Doel, Stockwell, Brent R, Yalowich, Jack C, Zhang, Xiaoli

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Constitutively Active Androgen Receptor in Hepatocellular Carcinoma von Montgomery, Emma J, Xing, Enming, Campbell, Moray J, Li, Pui-Kai, Blachly, James S, Tsung, Allan, Coss, Christopher C

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Development of selective androgen receptor modulators (SARMs) von Narayanan, Ramesh, Coss, Christopher C., Dalton, James T.

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Nonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic Benefit von Mohler, Michael L, Bohl, Casey E, Jones, Amanda, Coss, Christopher C, Narayanan, Ramesh, He, Yali, Hwang, Dong Jin, Dalton, James T, Miller, Duane D

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Decoupling FcRn and tumor contributions to elevated immune checkpoint inhibitor clearance in cancer cachexia von Vu, Trang T, Kim, Kyeongmin, Manna, Millennium, Thomas, Justin, Remaily, Bryan C, Montgomery, Emma J, Costa, Travis, Granchie, Lauren, Xie, Zhiliang, Guo, Yizhen, Chen, Min, Castillo, Alyssa Marie M, Kulp, Samuel K, Mo, Xiaokui, Nimmagadda, Sridhar, Gregorevic, Paul, Owen, Dwight H, Ganesan, Latha P, Mace, Thomas A, Coss, Christopher C, Phelps, Mitch A

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Inhibition of androgen/AR signaling inhibits diethylnitrosamine (DEN) induced tumour initiation and remodels liver immune cell networks von Helms, Timothy H., Mullins, Riley D., Thomas-Ahner, Jennifer M., Kulp, Samuel K., Campbell, Moray J., Lucas, Fabienne, Schmidt, Nathan, LeMoine, Dana M., Getaneh, Surafel, Xie, Zhiliang, Phelps, Mitch A., Clinton, Steven K., Coss, Christopher C.

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Phyllanthusmin Derivatives Induce Apoptosis and Reduce Tumor Burden in High-Grade Serous Ovarian Cancer by Late-Stage Autophagy Inhibition von Young, Alexandria N, Herrera, Denisse, Huntsman, Andrew C, Korkmaz, Melissa A, Lantvit, Daniel D, Mazumder, Sarmistha, Kolli, Shamalatha, Coss, Christopher C, King, Salane, Wang, Hongyan, Swanson, Steven M, Kinghorn, A Douglas, Zhang, Xiaoli, Phelps, Mitch A, Aldrich, Leslie N, Fuchs, James R, Burdette, Joanna E

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Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma von Yu, Peter Y, Gardner, Heather L, Roberts, Ryan, Cam, Hakan, Hariharan, Seethalakshmi, Ren, Ling, LeBlanc, Amy K, Xiao, Hui, Lin, Jiayuh, Guttridge, Denis C, Mo, Xiaokui, Bennett, Chad E, Coss, Christopher C, Ling, Yonghua, Phelps, Mitch A, Houghton, Peter, London, Cheryl A

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Selective Androgen Receptor Modulator Treatment Improves Muscle Strength and Body Composition and Prevents Bone Loss in Orchidectomized Rats von Gao, Wenqing, Reiser, Peter J, Coss, Christopher C, Phelps, Mitch A, Kearbey, Jeffrey D, Miller, Duane D, Dalton, James T

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Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor von Liva, Sophia G, Tseng, Yu‐Chou, Dauki, Anees M, Sovic, Michael G, Vu, Trang, Henderson, Sally E, Kuo, Yi‐Chiu, Benedict, Jason A, Zhang, Xiaoli, Remaily, Bryan C, Kulp, Samuel K, Campbell, Moray, Bekaii‐Saab, Tanios, Phelps, Mitchell A, Chen, Ching‐Shih, Coss, Christopher C

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The Neonatal Fc Receptor Is Elevated in Monocyte-Derived Immune Cells in Pancreatic Cancer von Thomas, Justin, Torok, Molly A, Agrawal, Kriti, Pfau, Timothy, Vu, Trang T, Lyberger, Justin, Chang, Hsiaochi, Castillo, Alyssa Marie M, Chen, Min, Remaily, Bryan, Kim, Kyeongmin, Xie, Zhiliang, Dillhoff, Mary E, Kulp, Samuel K, Behbehani, Gregory K, Cruz-Monserrate, Zobeida, Ganesan, Latha P, Owen, Dwight H, Phelps, Mitch A, Coss, Christopher C, Mace, Thomas A

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Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer von Datta, Jharna, Willingham, Natalie, Manouchehri, Jasmine M, Schnell, Patrick, Sheth, Mirisha, David, Joel J, Kassem, Mahmoud, Wilson, Tyler A, Radomska, Hanna S, Coss, Christopher C, Bennett, Chad E, Ganju, Ramesh K, Sardesai, Sagar D, Lustberg, Maryam, Ramaswamy, Bhuvaneswari, Stover, Daniel G, Cherian, Mathew A

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Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation von Narayanan, Ramesh, Yepuru, Muralimohan, Coss, Christopher C, Wu, Zhongzhi, Bauler, Matthew N, Barrett, Christina M, Mohler, Michael L, Wang, Yun, Kim, Juhyun, Snyder, Linda M, He, Yali, Levy, Nelson, Miller, Duane D, Dalton, James T

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Cachectic Cancer Patients: Immune to Checkpoint Inhibitor Therapy? von Coss, Christopher C, Clinton, Steven K, Phelps, Mitch A

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Function-Oriented Synthesis of Pentacyclic Triterpenoids and Discovery of an ent-Estrane as a Natural Product-Inspired Androgen Receptor Antagonist von Stempel, Zachary D., Radomska, Hanna S., Coss, Christopher C., Micalizio, Glenn C.

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Selective androgen receptor modulators for the treatment of late onset male hypogonadism von Coss, Christopher C, Jones, Amanda, Hancock, Michael L, Steiner, Mitchell S, Dalton, James T

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Merging Natural Product Structures with Pharmaceutical Leads: Unnatural Enantiomers of Estranes as Glucocorticoid Receptor Modulators That Suppress TNF‑α and IL‑6 Release von Nicholson, Joshua M., Yang, Dexi, Koelblen, Thomas, Hu, Eric L., Coss, Christopher C., Burris, Thomas P., Hu, Xiao, Micalizio, Glenn C.

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Letter to the Editor: Exposure–response or clearance–response relationship in immune checkpoint therapy?—A comment on ‘correlation between nivolumab exposure and treatment outcomes... von Badawi, Mohamed, Coss, Christopher C., Phelps, Mitch A.

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