Evolution of new enzymes by gene duplication and divergence von Copley, Shelley D.

Volltext

Shining a light on enzyme promiscuity von Copley, Shelley D

Volltext

An evolutionary biochemist's perspective on promiscuity von Copley, Shelley D.

Volltext

Moonlighting is mainstream: Paradigm adjustment required von Copley, Shelley D.

Volltext

Setting the stage for evolution of a new enzyme von Copley, Shelley D.

Volltext

Evolution of efficient pathways for degradation of anthropogenic chemicals von Copley, Shelley D

Volltext

Synonymous mutations make dramatic contributions to fitness when growth is limited by a weak-link enzyme von Kristofich, JohnCarlo, Morgenthaler, Andrew B, Kinney, Wallis R, Ebmeier, Christopher C, Snyder, Daniel J, Old, William M, Cooper, Vaughn S, Copley, Shelley D

Volltext

The physical basis and practical consequences of biological promiscuity von Copley, Shelley D

Volltext

Toward a Systems Biology Perspective on Enzyme Evolution von Copley, Shelley D.

Volltext

Reactivity landscape of pyruvate under simulated hydrothermal vent conditions von Novikov, Yehor, Copley, Shelley D.

Volltext

Inhibitory cross-talk upon introduction of a new metabolic pathway into an existing metabolic network von Kim, Juhan, Copley, Shelley D

Volltext

How to Recruit a Promiscuous Enzyme to Serve a New Function von Copley, Shelley D., Newton, Matilda S., Widney, Karl A.

Volltext

Challenging a decades-old paradigm: ProB and ProA do not channel the unstable intermediate in proline synthesis after all von Newton, Matilda S, Azadeh, Ashley L, Morgenthaler, Andrew B, Copley, Shelley D

Volltext

Enzymes with extra talents: moonlighting functions and catalytic promiscuity von Copley, Shelley D

Volltext

Amplicon Remodeling and Genomic Mutations Drive Population Dynamics after Segmental Amplification von Morgenthaler, Andrew B, Fritts, Ryan K, Copley, Shelley D

Volltext

Abstract 2250 The problematic intermediate that….isn't? von Copley, Shelley

Volltext

Synonymous edits in the Escherichia coli genome have substantial and condition-dependent effects on fitness von Yang, Dong-Dong, Rusch, Leo M, Widney, Karl A, Morgenthaler, Andrew B, Copley, Shelley D

Volltext

Differential effects of a mutation on the normal and promiscuous activities of orthologs: implications for natural and directed evolution von Khanal, Akhil, Yu McLoughlin, Sean, Kershner, Jamie P, Copley, Shelley D

Volltext

A versatile and highly efficient method for scarless genome editing in Escherichia coli and Salmonella enterica von Kim, Juhan, Webb, Anthony M, Kershner, Jamie P, Blaskowski, Stephen, Copley, Shelley D

Volltext

Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol von Yadid, Itamar, Rudolph, Johannes, Hlouchova, Klara, Copley, Shelley D

Volltext