Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells von Denman, Cecele J, Senyukov, Vladimir V, Somanchi, Srinivas S, Phatarpekar, Prasad V, Kopp, Lisa M, Johnson, Jennifer L, Singh, Harjeet, Hurton, Lenka, Maiti, Sourindra N, Huls, M Helen, Champlin, Richard E, Cooper, Laurence J N, Lee, Dean A

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Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity von Shah, Nina, Martin-Antonio, Beatriz, Yang, Hong, Ku, Stephanie, Lee, Dean A, Cooper, Laurence J N, Decker, William K, Li, Sufang, Robinson, Simon N, Sekine, Takuya, Parmar, Simrit, Gribben, John, Wang, Michael, Rezvani, Katy, Yvon, Eric, Najjar, Amer, Burks, Jared, Kaur, Indreshpal, Champlin, Richard E, Bollard, Catherine M, Shpall, Elizabeth J

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Engineering lymph node homing of ex vivo–expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7 von Somanchi, Srinivas S., Somanchi, Anitha, Cooper, Laurence J.N., Lee, Dean A.

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Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials von Jena, Bipulendu, Maiti, Sourindra, Huls, Helen, Singh, Harjeet, Lee, Dean A, Champlin, Richard E, Cooper, Laurence J N

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Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection von Kumaresan, Pappanaicken R., Manuri, Pallavi R., Albert, Nathaniel D., Maiti, Sourindra, Singh, Harjeet, Mi, Tiejuan, Roszik, Jason, Rabinovich, Brian, Olivares, Simon, Krishnamurthy, Janani, Zhang, Ling, Najjar, Amer M., Huls, M. Helen, Lee, Dean A., Champlin, Richard E., Kontoyiannis, Dimitrios P., Cooper, Laurence J. N.

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CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells von KOWOLIK, Claudia M, TOPP, Max S, GONZALEZ, Sergio, PFEIFFER, Timothy, OLIVARES, Simon, GONZALEZ, Nancy, SMITH, David D, FORMAN, Stephen J, JENSEN, Michael C, COOPER, Laurence J. N

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Reprogramming CD19-Specific T Cells with IL-21 Signaling Can Improve Adoptive Immunotherapy of B-Lineage Malignancies von SINGH, Harjeet, FIGLIOLA, Matthew J, CHAMPLIN, Richard E, COOPER, Laurence J. N, DAWSON, Margaret J, HULS, Helen, OLIVARES, Simon, SWITZER, Kirsten, MI, Tiejuan, MAITI, Sourindra, KEBRIAEI, Partow, LEE, Dean A

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Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters von Leekha, Ankita, Saeedi, Arash, Sefat, K M Samiur Rahman, Kumar, Monish, Martinez-Paniagua, Melisa, Damian, Adrian, Kulkarni, Rohan, Reichel, Kate, Rezvan, Ali, Masoumi, Shalaleh, Liu, Xinli, Cooper, Laurence J. N., Sebastian, Manu, Sands, Courtney M., Das, Vallabh E., Patel, Nimesh B., Hurst, Brett, Varadarajan, Navin

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An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models von Leekha, Ankita, Saeedi, Arash, Kumar, Monish, Sefat, K. M. Samiur Rahman, Martinez-Paniagua, Melisa, Meng, Hui, Fathi, Mohsen, Kulkarni, Rohan, Reichel, Kate, Biswas, Sujit, Tsitoura, Daphne, Liu, Xinli, Cooper, Laurence J. N., Sands, Courtney M., Das, Vallabh E., Sebastian, Manu, Hurst, Brett L., Varadarajan, Navin

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Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering von Zong, Shan, Mi, Tiejuan, Flores, 2nd, Leo G, Alpert, Amir, Olivares, Simon, Patel, Krina, Maiti, Sourindra, Mcnamara, George, Cooper, Laurence J N, Torikai, Hiroki

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Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations von Deniger, Drew C, Yu, Jianqiang, Huls, M Helen, Figliola, Matthew J, Mi, Tiejuan, Maiti, Sourindra N, Widhopf, 2nd, George F, Hurton, Lenka V, Thokala, Radhika, Singh, Harjeet, Olivares, Simon, Champlin, Richard E, Wierda, William G, Kipps, Thomas J, Cooper, Laurence J N

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Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor von Jena, Bipulendu, Dotti, Gianpietro, Cooper, Laurence J.N.

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Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer von Rabinovich, Brian A, Ye, Yang, Etto, Tamara, Chen, Jie Qing, Levitsky, Hyam I, Overwijk, Willem W, Cooper, Laurence J.N, Gelovani, Juri, Hwu, Patrick

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Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells von KAHLON, Kanwarpal S, BROWN, Christine, COOPER, Laurence J. N, RAUBITSCHEK, Andrew, FORMAN, Stephen J, JENSEN, Michael C

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Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells von Hurton, Lenka V., Singh, Harjeet, Najjar, Amer M., Switzer, Kirsten C., Mi, Tiejuan, Maiti, Sourindra, Olivares, Simon, Rabinovich, Brian, Huls, Helen, Forget, Marie-Andrée, Datar, Vrushali, Kebriaei, Partow, Lee, Dean A., Champlin, Richard E., Cooper, Laurence J. N.

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A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR von Torikai, Hiroki, Reik, Andreas, Liu, Pei-Qi, Zhou, Yuanyue, Zhang, Ling, Maiti, Sourindra, Huls, Helen, Miller, Jeffrey C., Kebriaei, Partow, Rabinovitch, Brian, Lee, Dean A., Champlin, Richard E., Bonini, Chiara, Naldini, Luigi, Rebar, Edward J., Gregory, Philip D., Holmes, Michael C., Cooper, Laurence J.N.

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Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010 von ERTL, Hildegund C. J, ZAIA, John, ROSENBERG, Steven A, JUNE, Carl H, DOTTI, Gianpietro, KAHN, Jeffrey, COOPER, Laurence J. N, CORRIGAN-CURAY, Jacqueline, STROME, Scott E

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Cord-Blood Engraftment with Ex Vivo Mesenchymal-Cell Coculture von de Lima, Marcos, McNiece, Ian, Robinson, Simon N, Munsell, Mark, Eapen, Mary, Horowitz, Mary, Alousi, Amin, Saliba, Rima, McMannis, John D, Kaur, Indreshpal, Kebriaei, Partow, Parmar, Simrit, Popat, Uday, Hosing, Chitra, Champlin, Richard, Bollard, Catherine, Molldrem, Jeffrey J, Jones, Roy B, Nieto, Yago, Andersson, Borje S, Shah, Nina, Oran, Betul, Cooper, Laurence J.N, Worth, Laura, Qazilbash, Muzaffar H, Korbling, Martin, Rondon, Gabriela, Ciurea, Stefan, Bosque, Doyle, Maewal, Ila, Simmons, Paul J, Shpall, Elizabeth J

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A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19 von Singh, Harjeet, Huls, Helen, Kebriaei, Partow, Cooper, Laurence J. N.

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Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells von Singh, Harjeet, Figliola, Matthew J, Dawson, Margaret J, Olivares, Simon, Zhang, Ling, Yang, Ge, Maiti, Sourindra, Manuri, Pallavi, Senyukov, Vladimir, Jena, Bipulendu, Kebriaei, Partow, Champlin, Richard E, Huls, Helen, Cooper, Laurence J N

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