Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened von Chen, James K, Taipale, Jussi, Cooper, Michael K, Beachy, Philip A

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Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development von Huang, Xi, Liu, Jiang, Ketova, Tatiana, Fleming, Jonathan T, Grover, Vandana K, Cooper, Michael K, Litingtung, Ying, Chiang, Chin

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Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade von Berman, David M., Karhadkar, Sunil S., Hallahan, Andrew R., Pritchard, Joel I., Eberhart, Charles G., Watkins, D. Neil, Chen, James K., Cooper, Michael K., Taipale, Jussi, Olson, James M., Beachy, Philip A.

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An In Vivo Chemical Genetic Screen Identifies Phosphodiesterase 4 as a Pharmacological Target for Hedgehog Signaling Inhibition von Williams, Charles H., Hempel, Jonathan E., Hao, Jijun, Frist, Audrey Y., Williams, Michelle M., Fleming, Jonathan T., Sulikowski, Gary A., Cooper, Michael K., Chiang, Chin, Hong, Charles C.

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Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics von Huang, Xi, Dubuc, Adrian M, Hashizume, Rintaro, Berg, Jim, He, Ye, Wang, Ji, Chiang, Chin, Cooper, Michael K, Northcott, Paul A, Taylor, Michael D, Barnes, Michael J, Tihan, Tarik, Chen, Justin, Hackett, Christopher S, Weiss, William A, James, C David, Rowitch, David H, Shuman, Marc A, Jan, Yuh Nung, Jan, Lily Yeh

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Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study von Buck, Jason R, McKinley, Eliot T, Fu, Allie, Abel, Ty W, Thompson, Reid C, Chambless, Lola, Watchmaker, Jennifer M, Harty, James P, Cooper, Michael K, Manning, H Charles

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Intertumoral Heterogeneity within Medulloblastoma Subgroups von Cavalli, Florence M.G., Remke, Marc, Rampasek, Ladislav, Peacock, John, Shih, David J.H., Luu, Betty, Garzia, Livia, Torchia, Jonathon, Nor, Carolina, Morrissy, A. Sorana, Agnihotri, Sameer, Thompson, Yuan Yao, Kuzan-Fischer, Claudia M., Farooq, Hamza, Isaev, Keren, Daniels, Craig, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Lee, Ji Yeoun, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Vasiljevic, Alexandre, Faure-Conter, Cecile, Jouvet, Anne, Giannini, Caterina, Nageswara Rao, Amulya A., Li, Kay Ka Wai, Ng, Ho-Keung, Eberhart, Charles G., Pollack, Ian F., Hamilton, Ronald L., Gillespie, G. Yancey, Olson, James M., Leary, Sarah, Weiss, William A., Lach, Boleslaw, Chambless, Lola B., Thompson, Reid C., Cooper, Michael K., Vibhakar, Rajeev, Hauser, Peter, van Veelen, Marie-Lise C., Kros, Johan M., French, Pim J., Ra, Young Shin, Kumabe, Toshihiro, López-Aguilar, Enrique, Zitterbart, Karel, Sterba, Jaroslav, Finocchiaro, Gaetano, Massimino, Maura, Van Meir, Erwin G., Osuka, Satoru, Shofuda, Tomoko, Klekner, Almos, Zollo, Massimo, Leonard, Jeffrey R., Rubin, Joshua B., Jabado, Nada, Albrecht, Steffen, Mora, Jaume, Van Meter, Timothy E., Jung, Shin, Moore, Andrew S., Hallahan, Andrew R., Chan, Jennifer A., Tirapelli, Daniela P.C., Carlotti, Carlos G., Fouladi, Maryam, Pimentel, José, Faria, Claudia C., Saad, Ali G., Massimi, Luca, Liau, Linda M., Wheeler, Helen, Nakamura, Hideo, Elbabaa, Samer K., Perezpeña-Diazconti, Mario, Chico Ponce de León, Fernando, Robinson, Shenandoah, Zapotocky, Michal, Lassaletta, Alvaro, Huang, Annie, Hawkins, Cynthia E., Tabori, Uri, Bouffet, Eric, Bartels, Ute, Dirks, Peter B., Rutka, James T., Bader, Gary D., Reimand, Jüri, Goldenberg, Anna, Ramaswamy, Vijay, Taylor, Michael D.

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Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation von Cheng, Frances Y, Huang, Xi, Sarangi, Anuraag, Ketova, Tatiana, Cooper, Michael K, Litingtung, Ying, Chiang, Chin

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Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response von Grover, Vandana K, Valadez, J Gerardo, Bowman, Aaron B, Cooper, Michael K

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Clustering of dystonia in some pedigrees with autosomal dominant essential tremor suggests the existence of a distinct subtype of essential tremor von Hedera, Peter, Phibbs, Fenna T, Fang, John Y, Cooper, Michael K, Charles, P David, Davis, Thomas L

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EAG2 potassium channel with evolutionarily conserved function as a brain tumor target von Huang, Xi, He, Ye, Dubuc, Adrian M, Hashizume, Rintaro, Zhang, Wei, Reimand, Jüri, Yang, Huanghe, Wang, Tongfei A, Stehbens, Samantha J, Younger, Susan, Barshow, Suzanne, Zhu, Sijun, Cooper, Michael K, Peacock, John, Ramaswamy, Vijay, Garzia, Livia, Wu, Xiaochong, Remke, Marc, Forester, Craig M, Kim, Charles C, Weiss, William A, James, C David, Shuman, Marc A, Bader, Gary D, Mueller, Sabine, Taylor, Michael D, Jan, Yuh Nung, Jan, Lily Yeh

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ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip von Lee, John J. Y., Tao, Ran, You, Zhen, Haldipur, Parthiv, Erickson, Anders W., Farooq, Hamza, Hendriske, Liam D., Abeysundara, Namal, Richman, Cory M., Wang, Evan Y., Das Gupta, Neha, Hadley, Jennifer, Batts, Melissa, Mount, Christopher W., Wu, Xiaochong, Rasnitsyn, Alex, Bailey, Swneke, Cavalli, Florence M. G., Morrissy, Sorana, Garzia, Livia, Michealraj, Kulandaimanuvel Antony, Visvanathan, Abhi, Fong, Vernon, Palotta, Jonelle, Suarez, Raul, Livingston, Bryn G., Liu, Miao, Luu, Betty, Daniels, Craig, Loukides, James, Bendel, Anne, French, Pim J., Kros, Johan M., Korshunov, Andrey, Kool, Marcel, Chico Ponce de León, Fernando, Perezpeña-Diazconti, Mario, Lach, Boleslaw, Singh, Sheila K., Leary, Sarah E. S., Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Lee, Ji-Yeoun, Tominaga, Teiji, Weiss, William A., Phillips, Joanna J., Dai, Shizhong, Zadeh, Gelareh, Saad, Ali G., Bognár, László, Klekner, Almos, Pollack, Ian F., Hamilton, Ronald L., Ra, Young-shin, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Thompson, Reid C., Kenney, Anna M., Cooper, Michael K., Mack, Stephen C., Jabado, Nada, Lupien, Mathieu, Gallo, Marco, Ramaswamy, Vijay, Suva, Mario L., Suzuki, Hiromichi, Millen, Kathleen J., Huang, L. Frank, Northcott, Paul A., Taylor, Michael D.

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine von Taipale, Jussi, Chen, James K., Cooper, Michael K., Wang, Baolin, Mann, Randall K., Milenkovic, Ljiljana, Scott, Matthew P., Beachy, Philip A.

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p75 Neurotrophin Receptor Cleavage by α- and γ-Secretases Is Required for Neurotrophin-mediated Proliferation of Brain Tumor-initiating Cells von Forsyth, Peter A., Krishna, Niveditha, Lawn, Samuel, Valadez, J. Gerardo, Qu, Xiaotao, Fenstermacher, David A., Fournier, Michelle, Potthast, Lisa, Chinnaiyan, Prakash, Gibney, Geoffrey T., Zeinieh, Michele, Barker, Philip A., Carter, Bruce D., Cooper, Michael K., Kenchappa, Rajappa S.

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Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling von Carlin, Dan, Sepich, Diane, Grover, Vandana K, Cooper, Michael K, Solnica-Krezel, Lilianna, Inbal, Adi

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Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling von Cooper, Michael K., Porter, Jeffery A., Young, Keith E., Beachy, Philip A.

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Cancer stem cells in glioma: challenges and opportunities von Wang, Jialiang, Ma, Yufang, Cooper, Michael K.

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A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis von Cooper, Michael K., Wassif, Christopher A., Krakowiak, Patrycja A., Taipale, Jussi, Gong, Ruoyu, Kelley, Richard I., Porter, Forbes D., Beachy, Philip A.

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Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation von Gerardo Valadez, J, Grover, Vandana K, Carter, Melissa D, Calcutt, M. Wade, Abiria, Sunday A, Lundberg, Christopher J, Williams, Thomas V, Cooper, Michael K

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Prevalence of unilateral tremor in autosomal dominant essential tremor von Phibbs, Fenna, Fang, John Y., Cooper, Michael K., Charles, David P., Davis, Thomas L., Hedera, Peter

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