Development of a Novel AOP for Cyp2F2-Mediated Lung Cancer in Mice von Hill, Thomas, Conolly, Rory B

Volltext

Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment von Perkins, Edward J., Ashauer, Roman, Burgoon, Lyle, Conolly, Rory, Landesmann, Brigitte, Mackay, Cameron, Murphy, Cheryl A., Pollesch, Nathan, Wheeler, James R., Zupanic, Anze, Scholz, Stefan

Volltext

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology von Conolly, Rory B, Ankley, Gerald T, Cheng, WanYun, Mayo, Michael L, Miller, David H, Perkins, Edward J, Villeneuve, Daniel L, Watanabe, Karen H

Volltext

Arsenic-Induced CarcinogenesisOxidative Stress as a Possible Mode of Action and Future Research Needs for More Biologically Based Risk Assessment von Kitchin, Kirk T, Conolly, Rory

Volltext

Pregnancy-specific physiologically-based toxicokinetic models for bisphenol A and bisphenol S von Gingrich, Jeremy, Filipovic, David, Conolly, Rory, Bhattacharya, Sudin, Veiga-Lopez, Almudena

Volltext

Bridging the Data Gap From in vitro Toxicity Testing to Chemical Safety Assessment Through Computational Modeling von Zhang, Qiang, Li, Jin, Middleton, Alistair, Bhattacharya, Sudin, Conolly, Rory B

Volltext

Updating the biologically based dose-response model for the nasal carcinogenicity of inhaled formaldehyde in the F344 rat von Conolly, Rory B, Schroeter, Jeffry, Kimbell, Julia S, Clewell, Harvey, Andersen, Melvin E, Gentry, P Robinan

Volltext

A Quantitative Source-to-Outcome Case Study To Demonstrate the Integration of Human Health and Ecological End Points Using the Aggregate Exposure Pathway and Adverse Outcome Pathwa... von Hines, David E, Conolly, Rory B, Jarabek, Annie M

Volltext

Relative contributions of endogenous and exogenous formaldehyde to formation of deoxyguanosine monoadducts and DNA-protein crosslink adducts of DNA in rat nasal mucosa von Conolly, Rory B, Campbell, Jerry L, Clewell, Harvey J, Schroeter, Jeffry, Kimbell, Julia S, Gentry, P Robinan

Volltext

A Case Study Application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) Frameworks to Facilitate the Integration of Human Health and Ecological End Point... von Hines, David E, Edwards, Stephen W, Conolly, Rory B, Jarabek, Annie M

Volltext

Case Study in 21st‐Century Ecotoxicology: Using In Vitro Aromatase Inhibition Data to Predict Reproductive Outcomes in Fish In Vivo von Villeneuve, Daniel L., Blackwell, Brett R., Blanksma, Chad A., Cavallin, Jenna E., Cheng, Wan‐Yun, Conolly, Rory B., Conrow, Kendra, Feifarek, David J., Heinis, Larry J., Jensen, Kathleen M., Kahl, Michael D., Milsk, Rebecca Y., Poole, Shane T., Randolph, Eric C., Saari, Travis W., Watanabe, Karen H., Ankley, Gerald T.

Volltext

Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses von Zhang, Qiang, Bhattacharya, Sudin, Conolly, Rory B, Clewell, Harvey J, Kaminski, Norbert E, Andersen, Melvin E

Volltext

A Physiologically Based Pharmacokinetic (PBPK) Modeling Framework for Mixtures of Dioxin-like Compounds von Liu, Rongrui, Zacharewski, Tim R, Conolly, Rory B, Zhang, Qiang

Volltext

Changes in Metabolites Present in Lung-Lining Fluid Following Exposure of Humans to Ozone von Cheng, WanYun, Duncan, Kelly E, Ghio, Andrew J, Ward-Caviness, Cavin, Karoly, Edward D, Diaz-Sanchez, David, Conolly, Rory B, Devlin, Robert B

Volltext

Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action von Ankley, Gerald T., Bencic, David C., Breen, Michael S., Collette, Timothy W., Conolly, Rory B., Denslow, Nancy D., Edwards, Stephen W., Ekman, Drew R., Garcia-Reyero, Natalia, Jensen, Kathleen M., Lazorchak, James M., Martinović, Dalma, Miller, David H., Perkins, Edward J., Orlando, Edward F., Villeneuve, Daniel L., Wang, Rong-Lin, Watanabe, Karen H.

Volltext

PBPK modeling to evaluate maximum tolerated doses: A case study with 3-chloroallyl alcohol von Conolly, Rory P, Clewell, Harvey J, Moore, Martha M, Campbell, Jerry L, Cheng, Wanyun, Gentry, R Robinan

Volltext

Nonmonotonic Dose-Response Relationships: Mechanistic Basis, Kinetic Modeling, and Implications for Risk Assessment von Conolly, Rory B., Lutz, Werner K.

Volltext

Effects of endogenous formaldehyde in nasal tissues on inhaled formaldehyde dosimetry predictions in the rat, monkey, and human nasal passages von Schroeter, Jeffry D, Campbell, Jerry, Kimbell, Julia S, Conolly, Rory B, Clewell, Harvey J, Andersen, Melvin E

Volltext

High-Throughput Video Processing of Heart Rate Responses in Multiple Wild-type Embryonic Zebrafish per Imaging Field von Martin, W. Kyle, Tennant, Alan H., Conolly, Rory B., Prince, Katya, Stevens, Joey S, DeMarini, David M., Martin, Brandi L., Thompson, Leslie C., Gilmour, M. Ian, Cascio, Wayne E., Hays, Michael D., Hazari, Mehdi S., Padilla, Stephanie, Farraj, Aimen K.

Volltext

Embracing systems toxicology at single-cell resolution von Zhang, Qiang, Caudle, W. Michael, Pi, Jingbo, Bhattacharya, Sudin, Andersen, Melvin E., Kaminski, Norbert E., Conolly, Rory B.

Volltext