Oral Metallo-Beta-Lactamase Protects the Gut Microbiome From Carbapenem-Mediated Damage and Reduces Propagation of Antibiotic Resistance in Pigs von Connelly, Sheila, Fanelli, Brian, Hasan, Nur A, Colwell, Rita R, Kaleko, Michael

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Development of SYN-004, an oral beta-lactamase treatment to protect the gut microbiome from antibiotic-mediated damage and prevent Clostridium difficile infection von Kaleko, Michael, Bristol, J. Andrew, Hubert, Steven, Parsley, Todd, Widmer, Giovanni, Tzipori, Saul, Subramanian, Poorani, Hasan, Nur, Koski, Perrti, Kokai-Kun, John, Sliman, Joseph, Jones, Annie, Connelly, Sheila

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Identification, Characterization, and Formulation of a Novel Carbapenemase Intended to Prevent Antibiotic-Mediated Gut Dysbiosis von Connelly, Sheila, Parsley, Todd, Ge, Hui, Kaleko, Michael

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SYN-007, an Orally Administered Beta-Lactamase Enzyme, Protects the Gut Microbiome from Oral Amoxicillin/Clavulanate without Adversely Affecting Antibiotic Systemic Absorption in D... von Connelly, Sheila, Fanelli, Brian, Hasan, Nur A., Colwell, Rita R., Kaleko, Michael

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Prior exposure to Bordetella species as an exclusion criterion in the baboon model of pertussis von NGUYEN, Annalee W., WAGNER, Ellen K., POSADA, Luciano, LIU, Xinlei, CONNELLY, Sheila, PAPIN, James F., WOLF, Roman F., KALEKO, Michael, MAYNARD, Jennifer A.

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Oral Beta-Lactamase Protects the Canine Gut Microbiome from Oral Amoxicillin-Mediated Damage von Connelly, Sheila, Fanelli, Brian, Hasan, Nur A, Colwell, Rita R, Kaleko, Michael

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Low dose oral beta-lactamase protects the gut microbiome from oral beta-lactam-mediated damage in dogs von Connelly, Sheila, Fanelli, Brian, Hasan, Nur A, Colwell, Rita R, Kaleko, Michael

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Day-Case Karydakis Flap for Pilonidal Sinus von Anderson, John H., Yip, Christina O., Nagabhushan, J. S., Connelly, Sheila J.

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Angiopoietin-2 enhances retinal vessel sensitivity to vascular endothelial growth factor von Oshima, Yuji, Deering, Tye, Oshima, Sachiko, Nambu, Hiroyuki, Reddy, P. Seshidhar, Kaleko, Michael, Connelly, Sheila, Hackett, Sean F., Campochiaro, Peter A.

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Sustained Human Factor VIII Expression in Hemophilia A Mice Following Systemic Delivery of a Gutless Adenoviral Vector von Reddy, P.Seshidhar, Sakhuja, Kiran, Ganesh, Shanthi, Yang, Lijuan, Kayda, Dawn, Brann, Terrence, Pattison, Scott, Golightly, Doug, Idamakanti, Neeraja, Pinkstaff, Anne, Kaloss, Michele, Barjot, Catherine, Chamberlain, Jeffrey S., Kaleko, Michael, Connelly, Sheila

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Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia... von Gallo-Penn, Angela M., Shirley, Pamela S., Andrews, Julie L., Tinlin, Shawn, Webster, Sandy, Cameron, Cherie, Hough, Christine, Notley, Colleen, Lillicrap, David, Kaleko, Michael, Connelly, Sheila

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Optimization of the generation and propagation of gutless adenoviral vectors von SAKHUJA, Kiran, SESHIDHAR REDDY, P, GANESH, Shanthi, CANTANIAG, Floro, PATTISON, Scott, LIMBACH, Paullin, KAYDA, Dawn B, KADAN, Michael J, KALEKO, Michael, CONNELLY, Sheila

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Distinct consequences of amoxicillin and ertapenem exposure in the porcine gut microbiome von Connelly, Sheila, Subramanian, Poorani, Hasan, Nur A., Colwell, Rita R., Kaleko, Michael

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1140 – Syn-007, an Oral Beta-Lactamase Prevents Gut Microbime Dysbiosis Caused by Oral Amoxicillin and Oral Amoxicillin/Clavulanate Without Affecting Amoxicillin Systemic Absorptio... von Connelly, Sheila, Freguia, Christian Furlan, Fanelli, Brian C., Hasan, Nur A., Colwell, Rita, Kaleko, Michael

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Treatment of Type 2 Diabetes by Adenoviral-Mediated Overexpression of the Glucokinase Regulatory Protein von SLOSBERG, Eric D, DESAI, Urvi J, FANELLI, Barbara, DENNY, Irene St, CONNELLY, Sheila, KALEKO, Michael, BOETTCHER, Brian R, CAPLAN, Shari L

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Sa1839 - Orally Delivered Beta-Lactamase Prevents Gut Microbiome Dysbiosis Caused by IV and Oral Antibiotics and Mitigates Propagation of Antibiotic Resistance in Porcine and Canin... von Kaleko, Michael, Freguia, Christian Furlan, Fanelli, Brian, Hasan, Nur A., Colwell, Rita, Connelly, Sheila

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Sustained phenotypic correction of murine hemophilia A by in vivo gene therapy von CONNELLY, S, ANDREWS, J. L, KALEKO, M, GALLO, A. M, KAYDA, D. B, JIAHUA QIAN, HOYER, L, KADAN, M. J, GORZIGLIA, M. I, TRAPNELL, B. C, MCCLELLAND, A

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Generation and Characterization of E1/E2a/E3/E4-Deficient Adenoviral Vectors Encoding Human Factor VIII von Andrews, Julie L., Kadan, Michael J., Gorziglia, Mario I., Kaleko, Michael, Connelly, Sheila

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Phenotypic Correction of Diabetic Mice by Adenovirus-Mediated Glucokinase Expression von DESAI, Urvi J, SLOSBERG, Eric D, BOETTCHER, Brian R, CAPLAN, Shari L, FANELLI, Barbara, STEPHAN, Zouhair, GUNTHER, Vicky J, KALEKO, Michael, CONNELLY, Sheila

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332g - An Orally Delivered Beta-Lactamase Protects the Gut Microbiome from Antibiotic-Mediated Damage and Mitigates the Propagation of Antibiotic-Resistance Genes in a Porcine Dysb... von Connelly, Sheila, Freguia, Christian Furlan, Subramanian, Poorani, Hasan, Nur A., Colwell, Rita R., Kaleko, Michael

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