Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies von Apicella, Maria, Giannoni, Elisa, Fiore, Stephany, Ferrari, Karin Johanna, Fernández-Pérez, Daniel, Isella, Claudio, Granchi, Carlotta, Minutolo, Filippo, Sottile, Antonino, Comoglio, Paolo Maria, Medico, Enzo, Pietrantonio, Filippo, Volante, Marco, Pasini, Diego, Chiarugi, Paola, Giordano, Silvia, Corso, Simona

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The MET Oncogene: Thirty Years of Insights into Molecular Mechanisms Driving Malignancy von Crepaldi, Tiziana, Gallo, Simona, Comoglio, Paolo Maria

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MET and KRAS Gene Amplification Mediates Acquired Resistance to MET Tyrosine Kinase Inhibitors von CEPERO, Virna, SIERRA, J. Rafael, CORSO, Simona, GHISO, Elena, CASORZO, Laura, PERERA, Tim, COMOGLIO, Paolo Maria, GIORDANO, Silvia

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Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages von Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia

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The ROR1 pseudokinase diversifies signaling outputs in MET‐addicted cancer cells von Gentile, Alessandra, Lazzari, Luca, Benvenuti, Silvia, Trusolino, Livio, Comoglio, Paolo Maria

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MET Oncogene Enhances Pro-Migratory Functions by Counteracting NMDAR2B Cleavage von Gallo, Simona, Vitacolonna, Annapia, Comoglio, Paolo Maria, Crepaldi, Tiziana

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Efficacy of CAR-T immunotherapy in MET overexpressing tumors not eligible for anti-MET targeted therapy von Chiriaco, Cristina, Donini, Chiara, Cortese, Marco, Ughetto, Stefano, Modica, Chiara, Martinelli, Ilaria, Proment, Alessia, Vitali, Letizia, Fontani, Lara, Casucci, Monica, Comoglio, Paolo Maria, Giordano, Silvia, Sangiolo, Dario, Leuci, Valeria, Vigna, Elisa

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The PSI Domain of the MET Oncogene Encodes a Functional Disulfide Isomerase Essential for the Maturation of the Receptor Precursor von Altintas, Dogus Murat, Gallo, Simona, Basilico, Cristina, Cerqua, Marina, Bocedi, Alessio, Vitacolonna, Annapia, Botti, Orsola, Casanova, Elena, Rancati, Ilaria, Milanese, Chiara, Notari, Sara, Gambardella, Giorgia, Ricci, Giorgio, Mastroberardino, Pier Giorgio, Boccaccio, Carla, Crepaldi, Tiziana, Comoglio, Paolo Maria

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The Long-Lasting Protective Effect of HGF in Cardiomyoblasts Exposed to Doxorubicin Requires a Positive Feed-Forward Loop Mediated by Erk1,2-Timp1-Stat3 von Gallo, Simona, Spilinga, Martina, Casanova, Elena, Bonzano, Alessandro, Boccaccio, Carla, Comoglio, Paolo Maria, Crepaldi, Tiziana

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Interplay between scatter factor receptors and B plexins controls invasive growth von CONROTTO, Paolo, CORSO, Simona, GAMBERINI, Sara, COMOGLIO, Paolo Maria, GIORDANO, Silvia

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Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor von Desole, Claudia, Gallo, Simona, Vitacolonna, Annapia, Vigna, Elisa, Basilico, Cristina, Montarolo, Francesca, Zuppini, Francesca, Casanova, Elena, Miggiano, Riccardo, Ferraris, Davide Maria, Bertolotto, Antonio, Comoglio, Paolo Maria, Crepaldi, Tiziana

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Trastuzumab and lapatinib in HER2-amplified metastatic colorectal cancer patients (mCRC): The HERACLES trial von Siena, Salvatore, Sartore-Bianchi, Andrea, Lonardi, Sara, Trusolino, Livio, Martino, Cosimo, Bencardino, Katia, Leone, Francesco, Zagonel, Vittorina, Valtorta, Emanuele, Torri, Valter, Siravegna, Giulia, Amatu, Alessio, Bonazzina, Erica Francesca, Rusconi, Francesca, Ghezzi, Silvia, Ciardiello, Fortunato, Veronese, Silvio, Comoglio, Paolo Maria, Bardelli, Alberto, Marsoni, Silvia

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Genetic targeting of the kinase activity of the Met receptor in cancer cells von Arena, Sabrina, Pisacane, Alberto, Mazzone, Massimiliano, Comoglio, Paolo Maria, Bardelli, Alberto

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RON tyrosine kinase mutations in brain metastases from lung cancer von Milan, Melissa, Benvenuti, Silvia, Balderacchi, Alice Maria, Virzì, Anna Rita, Gentile, Alessandra, Senetta, Rebecca, Cassoni, Paola, Comoglio, Paolo Maria, Stella, Giulia Maria

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Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells von IVAN, M, BOND, J. A, PRAT, M, COMOGLIO, P. M, WYNFORD-THOMAS, D

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Activation of the MET receptor attenuates doxorubicin‐induced cardiotoxicity in vivo and in vitro von Gallo, Simona, Spilinga, Martina, Albano, Raffaella, Ferrauto, Giuseppe, Di Gregorio, Enza, Casanova, Elena, Balmativola, Davide, Bonzano, Alessandro, Boccaccio, Carla, Sapino, Anna, Comoglio, Paolo Maria, Crepaldi, Tiziana

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Abstract 3606: Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence von Martin, Valentina, Corso, Simona, Comoglio, Paolo Maria, Giordano, Silvia

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Cell Motility Is Controlled by SF2/ASF through Alternative Splicing of the Ron Protooncogene von Ghigna, Claudia, Giordano, Silvia, Shen, Haihong, Benvenuto, Federica, Castiglioni, Fabio, Comoglio, Paolo Maria, Green, Michael R., Riva, Silvano, Biamonti, Giuseppe

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Sema4D induces angiogenesis through Met recruitment by Plexin B1 von Conrotto, Paolo, Valdembri, Donatella, Corso, Simona, Serini, Guido, Tamagnone, Luca, Comoglio, Paolo Maria, Bussolino, Federico, Giordano, Silvia

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A chimeric antibody (MV-DN30) inhibiting von Vigna, Elisa, Petronzelli, Fiorella, Giordano, Silvia, Comoglio, Paolo Maria

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