The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex von He, Yupeng, Selvaraju, Sujatha, Curtin, Michael L, Jakob, Clarissa G, Zhu, Haizhong, Comess, Kenneth M, Shaw, Bailin, The, Juliana, Lima-Fernandes, Evelyne, Szewczyk, Magdalena M, Cheng, Dong, Klinge, Kelly L, Li, Huan-Qiu, Pliushchev, Marina, Algire, Mikkel A, Maag, David, Guo, Jun, Dietrich, Justin, Panchal, Sanjay C, Petros, Andrew M, Sweis, Ramzi F, Torrent, Maricel, Bigelow, Lance J, Senisterra, Guillermo, Li, Fengling, Kennedy, Steven, Wu, Qin, Osterling, Donald J, Lindley, David J, Gao, Wenqing, Galasinski, Scott, Barsyte-Lovejoy, Dalia, Vedadi, Masoud, Buchanan, Fritz G, Arrowsmith, Cheryl H, Chiang, Gary G, Sun, Chaohong, Pappano, William N

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Emerging Approaches for the Identification of Protein Targets of Small Molecules - A Practitioners’ Perspective von Comess, Kenneth M, McLoughlin, Shaun M, Oyer, Jon A, Richardson, Paul L, Stöckmann, Henning, Vasudevan, Anil, Warder, Scott E

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The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity von Bromberg, Kenneth D, Mitchell, Taylor R H, Upadhyay, Anup K, Jakob, Clarissa G, Jhala, Manisha A, Comess, Kenneth M, Lasko, Loren M, Li, Conglei, Tuzon, Creighton T, Dai, Yujia, Li, Fengling, Eram, Mohammad S, Nuber, Alexander, Soni, Niru B, Manaves, Vlasios, Algire, Mikkel A, Sweis, Ramzi F, Torrent, Maricel, Schotta, Gunnar, Sun, Chaohong, Michaelides, Michael R, Shoemaker, Alex R, Arrowsmith, Cheryl H, Brown, Peter J, Santhakumar, Vijayaratnam, Martin, Alberto, Rice, Judd C, Chiang, Gary G, Vedadi, Masoud, Barsyte-Lovejoy, Dalia, Pappano, William N

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A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation von Ojo, Kayode K., Eastman, Richard T., Vidadala, RamaSubbaRao, Zhang, Zhongsheng, Rivas, Kasey L., Choi, Ryan, Lutz, Justin D., Reid, Molly C., Fox, Anna M. W., Hulverson, Matthew A., Kennedy, Mark, Isoherranen, Nina, Kim, Laura M., Comess, Kenneth M., Kempf, Dale J., Verlinde, Christophe L. M. J., Su, Xin-zhuan, Kappe, Stefan H. I., Maly, Dustin J., Fan, Erkang, Van Voorhis, Wesley C.

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Discovery of a novel small molecule binding site of human survivin von Wendt, Michael D., Sun, Chaohong, Kunzer, Aaron, Sauer, Daryl, Sarris, Kathy, Hoff, Ethan, Yu, Liping, Nettesheim, David G., Chen, Jun, Jin, Sha, Comess, Kenneth M., Fan, Yihong, Anderson, Steven N., Isaac, Binumol, Olejniczak, Edward T., Hajduk, Philip J., Rosenberg, Saul H., Elmore, Steven W.

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Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design von Dietrich, Justin D, Longenecker, Kenton L, Wilson, Noel S, Goess, Christian, Panchal, Sanjay C, Swann, Steven L, Petros, Andrew M, Hobson, Adrian D, Ihle, David, Song, Danying, Richardson, Paul, Comess, Kenneth M, Cox, Philip B, Dombrowski, Amanda, Sarris, Kathy, Donnelly-Roberts, Diana L, Duignan, David B, Gomtsyan, Arthur, Jung, Paul, Krueger, A Chris, Mathieu, Suzanne, McClure, Andrea, Stoll, Vincent S, Wetter, Jill, Mankovich, John A, Hajduk, Philip J, Vasudevan, Anil, Stoffel, Robert H, Sun, Chaohong

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Quantitative, Real-Time Measurements of Intracellular Target Engagement Using Energy Transfer von Robers, Matthew B., Vasta, James D., Corona, Cesear R., Ohana, Rachel Friedman, Hurst, Robin, Jhala, Manisha A., Comess, Kenneth M., Wood, Keith V.

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An Ultraefficient Affinity-Based High-Throughout Screening Process: Application to Bacterial Cell Wall Biosynthesis Enzyme MurF von Comess, Kenneth M., Schurdak, Mark E., Voorbach, Martin J., Coen, Michael, Trumbull, Jonathan D., Yang, Houjun, Gao, Lan, Tang, Hua, Cheng, Xueheng, Lerner, Claude G., Mccall, J. Owen, Burns, David J., Beutel, Bruce A.

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Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms von Qian, Jie, Voorbach, Martin J, Huth, Jeffrey R, Coen, Michael L, Zhang, Haichao, Ng, Shi-Chung, Comess, Kenneth M, Petros, Andrew M, Rosenberg, Saul H, Warrior, Usha, Burns, David J

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Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5‑Aminopyrazole-4-carboxamide Scaffold von Zhang, Zhongsheng, Ojo, Kayode K, Vidadala, RamaSubbaRao, Huang, Wenlin, Geiger, Jennifer A, Scheele, Suzanne, Choi, Ryan, Reid, Molly C, Keyloun, Katelyn R, Rivas, Kasey, Kallur Siddaramaiah, Latha, Comess, Kenneth M, Robinson, Kenneth P, Merta, Philip J, Kifle, Lemma, Hol, Wim G. J, Parsons, Marilyn, Merritt, Ethan A, Maly, Dustin J, Verlinde, Christophe L. M. J, Van Voorhis, Wesley C, Fan, Erkang

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Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases von Comess, Kenneth M, Sun, Chaohong, Abad-Zapatero, Cele, Goedken, Eric R, Gum, Rebecca J, Borhani, David W, Argiriadi, Maria, Groebe, Duncan R, Jia, Yong, Clampit, Jill E, Haasch, Deanna L, Smith, Harriet T, Wang, Sanyi, Song, Danying, Coen, Michael L, Cloutier, Timothy E, Tang, Hua, Cheng, Xueheng, Quinn, Christopher, Liu, Bo, Xin, Zhili, Liu, Gang, Fry, Elizabeth H, Stoll, Vincent, Ng, Teresa I, Banach, David, Marcotte, Doug, Burns, David J, Calderwood, David J, Hajduk, Philip J

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Development of a High-Content Screening Assay Panel to Accelerate Mechanism of Action Studies for Oncology Research von Towne, Danli L., Nicholl, Emily E., Comess, Kenneth M., Galasinski, Scott C., Hajduk, Philip J., Abraham, Vivek C.

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Replication inhibition and translesion synthesis on templates containing site- specifically placed cis-diamminedichloroplatinum(II) DNA adducts von Comess, Kenneth M, Burstyn, Judith N, Essigmann, John M, Lippard, Stephen J

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A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding von Sako, Dianne, Comess, Kenneth M., Barone, Karen M., Camphausen, Raymond T., Cumming, Dale A., Shaw, Gray D.

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Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties von Kawai, Megumi, BaMaung, Nwe Y., Fidanze, Steve D., Erickson, Scott A., Tedrow, Jason S., Sanders, William J., Vasudevan, Anil, Park, Chang, Hutchins, Charles, Comess, Kenneth M., Kalvin, Douglas, Wang, Jieyi, Zhang, Qian, Lou, Pingping, Tucker-Garcia, Lora, Bouska, Jennifer, Bell, Randy L., Lesniewski, Richard, Henkin, Jack, Sheppard, George S.

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NMR-Driven Discovery of Benzoylanthranilic Acid Inhibitors of Far Upstream Element Binding Protein Binding to the Human Oncogene c-myc Promoter von Huth, Jeffrey R, Yu, Liping, Collins, Irene, Mack, Jamey, Mendoza, Renaldo, Isaac, Binumol, Braddock, Demetrios T, Muchmore, Steven W, Comess, Kenneth M, Fesik, Stephen W, Clore, G. Marius, Levens, David, Hajduk, Philip J

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Kinase Drug Discovery by Affinity Selection/Mass Spectrometry (ASMS): Application to DNA Damage Checkpoint Kinase Chk1 von Comess, Kenneth M., Trumbull, Jonathan D., Park, Chang, Chen, Zehan, Judge, Russell A., Voorbach, Martin J., Coen, Michael, Gao, Lan, Tang, Hua, Kovar, Peter, Cheng, Xueheng, Schurdak, Mark E., Zhang, Haiying, Sowin, Tom, Burns, David J.

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From Bacterial Genomes to Novel Antibacterial Agents: Discovery, Characterization, and Antibacterial Activity of Compounds that Bind to HI0065 (YjeE) from Haemophilus influenzae von Lerner, Claude G., Hajduk, Philip J., Wagner, Rolf, Wagenaar, Frank L., Woodall, Charlotte, Gu, Yu‐Gui, Searle, Xenia B., Florjancic, Alan S., Zhang, Tianyuan, Clark, Richard F., Cooper, Curt S., Mack, Jamey C., Yu, Liping, Cai, Mengli, Betz, Steven F., Chovan, Linda E., McCall, J. Owen, Black‐Schaefer, Candace L., Kakavas, Stephan J., Schurdak, Mark E., Comess, Kenneth M., Walter, Karl A., Edalji, Rohinton, Dorwin, Sarah A., Smith, Richard A., Hebert, Eric J., Harlan, John E., Metzger, Randy E., Merta, Philip J., Baranowski, John L., Coen, Michael L., Thornewell, Susan J., Shivakumar, Annapur G., Saiki, Anne Y., Soni, Niru, Bui, Mai, Balli, Darlene J., Sanders, William J., Nilius, Angela M., Holzman, Thomas F., Fesik, Stephen W., Beutel, Bruce A.

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Erratum: The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex von He, Yupeng, Selvaraju, Sujatha, Curtin, Michael L, Jakob, Clarissa G, Zhu, Haizhong, Comess, Kenneth M, Shaw, Bailin, The, Juliana, Lima-Fernandes, Evelyne, Szewczyk, Magdalena M, Cheng, Dong, Klinge, Kelly L, Li, Huan-Qiu, Pliushchev, Marina, Algire, Mikkel A, Maag, David, Guo, Jun, Dietrich, Justin, Panchal, Sanjay C, Petros, Andrew M, Sweis, Ramzi F, Torrent, Maricel, Bigelow, Lance J, Senisterra, Guillermo, Li, Fengling, Kennedy, Steven, Wu, Qin, Osterling, Donald J, Lindley, David J, Gao, Wenqing, Galasinski, Scott, Barsyte-Lovejoy, Dalia, Vedadi, Masoud, Buchanan, Fritz G, Arrowsmith, Cheryl H, Chiang, Gary G, Sun, Chaohong, Pappano, William N

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Identification and characterization of a novel linkage isomerization in the reaction of trans-diamminedichloroplatinum(II) with 5'-d(TCTACGCGTTCT) von Comess, Kenneth M, Costello, Catherine E, Lippard, Stephen J

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