Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial von Kanes, Stephen, MD, Colquhoun, Helen, MD, Gunduz-Bruce, Handan, MD, Raines, Shane, Arnold, Ryan, DO, Schacterle, Amy, PhD, Doherty, James, PhD, Epperson, C Neill, Prof, Deligiannidis, Kristina M, MD, Riesenberg, Robert, MD, Hoffmann, Ethan, Rubinow, David, Prof, Jonas, Jeffrey, MD, Paul, Steven, MD, Meltzer-Brody, Samantha, Dr

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Brexanolone as adjunctive therapy in super‐refractory status epilepticus von Rosenthal, Eric S., Claassen, Jan, Wainwright, Mark S., Husain, Aatif M., Vaitkevicius, Henrikas, Raines, Shane, Hoffmann, Ethan, Colquhoun, Helen, Doherty, James J., Kanes, Stephen J.

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Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials von Meltzer-Brody, Samantha, Colquhoun, Helen, Riesenberg, Robert, Epperson, C Neill, Deligiannidis, Kristina M, Rubinow, David R, Li, Haihong, Sankoh, Abdul J, Clemson, Christine, Schacterle, Amy, Jonas, Jeffrey, Kanes, Stephen

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850: Evaluation of breast milk concentrations following brexanolone iv administration to healthy lactating women von Hoffmann, Ethan, Wald, Jeff, Colquhoun, Helen

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Allopregnanolone Concentrations in Breast Milk and Plasma from Healthy Volunteers Receiving Brexanolone Injection, With Population Pharmacokinetic Modeling of Potential Relative In... von Wald, Jeffrey, Henningsson, Anja, Hanze, Eva, Hoffmann, Ethan, Li, Haihong, Colquhoun, Helen, Deligiannidis, Kristina M.

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Open‐label, proof‐of‐concept study of brexanolone in the treatment of severe postpartum depression von Kanes, Stephen J., Colquhoun, Helen, Doherty, James, Raines, Shane, Hoffmann, Ethan, Rubinow, David R., Meltzer‐Brody, Samantha

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Hemodynamic properties of SAGE-547 in patients with super-refractory status epilepticus: results from a phase 1/2 clinical trial (P6.234) von Colquhoun, Helen, Raines, Shane, Kanes, Stephen

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Brexanolone Injection Administration to Lactating Women: Breast Milk Allopregnanolone Levels [30J] von Hoffmann, Ethan, Wald, Jeffrey, Dray, Danielle, Colquhoun, Helen

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SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies von Hoffmann, Ethan, Nomikos, George G., Kaul, Inder, Raines, Shane, Wald, Jeff, Bullock, Amy, Sankoh, Abdul J., Doherty, James, Kanes, Stephen J., Colquhoun, Helen

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Quantitative Burst Suppression as a Biomarker in the Phase 2 Trial of SAGE-547: Lessons Learned for the First International Phase 3, Randomized, Controlled Trial for Super-Refracto... von Rosenthal, Eric, Colquhoun, Helen, Quirk, Michael

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SAGE-217, A Novel GABA A Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies von Hoffmann, Ethan, Nomikos, George G, Kaul, Inder, Raines, Shane, Wald, Jeff, Bullock, Amy, Sankoh, Abdul J, Doherty, James, Kanes, Stephen J, Colquhoun, Helen

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Insights on GABAergic Mechanism of PPD from Pivotal Studies of Brexanolone Injection and SAGE-217 [18E] von Meltzer-Brody, Samantha, Deligiannidis, Kristina, Colquhoun, Helen, Gunduz-Bruce, Handan, Dray, Danielle, Kanes, Stephen

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Brexanolone injection for post-partum depression treatment – Authors' reply von Meltzer-Brody, Samantha, Colquhoun, Helen, Doherty, James, Rubinow, David R, Kanes, Stephen

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Pharmacokinetics of SAGE-547 in patients with super refractory status epilepticus (P6.241) von Colquhoun, Helen, Hoffmann, Ethan, Raines, Shane, Wald, Jeffrey, Kanes, Stephen

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Phase 2 Data Suggest Heterogeneity of Presentation and Comorbidity Burden Do Not Impact Activity of SAGE-547 in Patients with Super-Refractory Status Epilepticus (P4.210) von Colquhoun, Helen, Baird, Mollie, Raines, Shane, Jonas, Jeffrey, Kanes, Steve

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F73. Efficacy of Brexanolone Injection in Subjects With Postpartum Depression With and Without Baseline Antidepressant Therapy: Insights From an Integrated Analysis of Three Pivota... von Meltzer-Brody, Samantha, Colquhoun, Helen, Riesenberg, Robert, Epperson, Nell, Deligiannidis, Kristina, Rubinow, David, Li, Haihong, Clemson, Christine, Kanes, Stephen

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Phase 3 Study Evaluating Brexanolone, a GABAA Receptor Modulator, in Severe Postpartum Depression [29B] von Meltzer-Brody, Samantha, Kanes, Stephen, Riesenberg, Robert, Rubinow, David, Maximos, Bassem, Colquhoun, Helen

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Phase 3 Study Evaluating Brexanolone, a GABAA Receptor Modulator, in Moderate Postpartum Depression [25H] von Kanes, Stephen, Colquhoun, Helen, Riesenberg, Robert, Rubinow, David, Maximos, Bassem, Meltzer-Brody, Samantha

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86: Brexanolone iv efficacy in postpartum depression in three pivotal trials: montgomery-åsberg depression rating scale assessment von Clemson, Christine, Meltzer-Brody, Samantha, Colquhoun, Helen, Riesenberg, Robert, Epperson, C.Neil, Deligiannidis, Kristina, Rubinow, David, Li, Haihong, Kanes, Stephen

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1068: Insights on GABAergic mechanism of postpartum depression from pivotal studies of brexanolone injection and SAGE-217 von Weedin, Nathan, Meltzer-Brody, Samantha, Deligiannidis, Kristina, Colquhoun, Helen, Lasser, Robert, Gunduz-Bruce, Handan, Eldar-Lissai, Adi, Sankoh, Abdul, Kanes, Stephen

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