Anti-PD-L1 and anti-CD73 combination therapy promotes T cell response to EGFR-mutated NSCLC von Tu, Eric, McGlinchey, Kelly, Wang, Jixin, Martin, Philip, Ching, Steven Lk, Floc'h, Nicolas, Kurasawa, James, Starrett, Jacqueline H, Lazdun, Yelena, Wetzel, Leslie, Nuttall, Barrett, Ng, Felicia Sl, Coffman, Karen T, Smith, Paul D, Politi, Katerina, Cooper, Zachary A, Streicher, Katie

Volltext

Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2–positive human xenograft models as a single agent and in... von Leow, Ching Ching, Chesebrough, Jon, Coffman, Karen T, Fazenbaker, Christine A, Gooya, John, Weng, David, Coats, Steve, Jackson, Dowdy, Jallal, Bahija, Chang, Yong

Volltext

Antibody-Dependent Cell-Mediated Cytotoxicity Effector-Enhanced EphA2 Agonist Monoclonal Antibody Demonstrates Potent Activity against Human Tumors von Bruckheimer, Elizabeth M., Fazenbaker, Christine A., Gallagher, Sandra, Mulgrew, Kathy, Fuhrmann, Stacy, Coffman, Karen T., Walsh, William, Ready, Shannon, Cook, Kim, Damschroder, Melissa, Kinch, Michael, Kiener, Peter A., Woods, Rob, Gao, Changshou, Dall'Acqua, William, Wu, Herren, Coats, Steven

Volltext

Efficacy and Antivascular Effects of EphA2 Reduction With an Agonistic Antibody in Ovarian Cancer von Landen, Charles N., Lu, Chunhua, Han, Liz Y., Coffman, Karen T., Bruckheimer, Elizabeth, Halder, Jyotsnabaran, Mangala, Lingegowda S., Merritt, William M., Lin, Yvonne G., Gao, Changhou, Schmandt, Rosemarie, Kamat, Aparna A., Li, Yang, Thaker, Premal, Gershenson, David M., Parikh, Nila U., Gallick, Gary E., Kinch, Michael S., Sood, Anil K.

Volltext

Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer von Merritt, William M., Kamat, Aparna A., Hwang, Jee-Young, Bottsford-Miller, Justin, Lu, Chunhua, Lin, Yvonne G., Coffey, Donna, Spannuth, Whitney A., Nugent, Elizabeth, Han, Liz Y., Landen, Charles N., Nick, Alpa M., Stone, Rebecca L., Coffman, Karen, Bruckheimer, Elizabeth, Broaddus, Russell R., Gershenson, David M., Coleman, Robert L., Sood, Anil K.

Volltext

Differential EphA2 epitope display on normal Versus malignant cells von COFFMAN, Karen T, MIN HU, KINCH, Michael S, CARLES-KINCH, Kelly, TICE, David, DONACKI, Nanci, MUNYON, Karyn, KIFLE, Giza, WOODS, Robert, LANGERMANN, Solomon, KIENER, Peter A

Volltext

Effects of the cyclooxygenase inhibitor, piroxicam, in combination with chemotherapy on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary blad... von Mohammed, Sulma I, Craig, Bruce A, Mutsaers, Anthony J, Glickman, Nita W, Snyder, Paul W, deGortari, Amalia E, Schlittler, Deborah L, Coffman, Karen T, Bonney, Patty L, Knapp, Deborah W

Volltext

Effects of the Cyclooxygenase Inhibitor, Piroxicam, in Combination with Chemotherapy on Tumor Response, Apoptosis, and Angiogenesis in a Canine Model of Human Invasive Urinary Blad... von Sulma I. Mohammed, Bruce A. Craig, Anthony J. Mutsaers, Nita W. Glickman, Paul W. Snyder, Amalia E. deGortari, Deborah L. Schlittler, Karen T. Coffman, Patty L. Bonney, Deborah W. Knapp

Volltext

Green Roofs as Urban Ecosystems: Ecological Structures, Functions, and Services von OBERNDORFER, ERICA, LUNDHOLM, JEREMY, BASS, BRAD, COFFMAN, REID R, DOSHI, HITESH, DUNNETT, NIGEL, GAFFIN, STUART, KÖHLER, MANFRED, LIU, KAREN K. Y, ROWE, BRADLEY

Volltext

An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19 von Owen, Dafydd R, Allerton, Charlotte M N, Anderson, Annaliesa S, Aschenbrenner, Lisa, Avery, Melissa, Berritt, Simon, Boras, Britton, Cardin, Rhonda D, Carlo, Anthony, Coffman, Karen J, Dantonio, Alyssa, Li, Di, Eng, Heather, Ferre, RoseAnn, Gajiwala, Ketan S, Gibson, Scott A, Greasley, Samantha E, Hurst, Brett L, Kadar, Eugene P, Kalgutkar, Amit S, Lee, Jack C, Lee, Jisun, Liu, Wei, Mason, Stephen W, Noell, Stephen, Novak, Jonathan J, Obach, R Scott, Ogilvie, Kevin, Patel, Nandini C, Pettersson, Martin, Rai, Devendra K, Reese, Matthew R, Sammons, Matthew F, Sathish, Jean G, Singh, Ravi Shankar P, Steppan, Claire M, Stewart, Al E, Tuttle, Jamison B, Updyke, Lawrence, Verhoest, Patrick R, Wei, Liuqing, Yang, Qingyi, Zhu, Yuao

Volltext

Discovery and Preclinical Profiling of 3‑[4-(Morpholin-4-yl)‑7H‑pyrrolo[2,3‑d]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Ac... von Henderson, Jaclyn L., Kormos, Bethany L., Hayward, Matthew M., Coffman, Karen J., Jasti, Jayasankar, Kurumbail, Ravi G., Wager, Travis T., Verhoest, Patrick R., Noell, G. Stephen, Chen, Yi, Needle, Elie, Berger, Zdenek, Steyn, Stefanus J., Houle, Christopher, Hirst, Warren D., Galatsis, Paul

Volltext

Phase II clinical trial of metformin as a cancer stem cell-targeting agent in ovarian cancer von Brown, Jason R, Chan, Daniel K, Shank, Jessica J, Griffith, Kent A, Fan, Huihui, Szulawski, Robert, Yang, Kun, Reynolds, R Kevin, Johnston, Carolyn, McLean, Karen, Uppal, Shitanshu, Liu, J Rebecca, Cabrera, Lourdes, Taylor, Sarah E, Orr, Brian C, Modugno, Francesmary, Mehta, Pooja, Bregenzer, Michael, Mehta, Geeta, Shen, Hui, Coffman, Lan G, Buckanovich, Ronald J

Volltext

Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth von McLean, Karen, Tan, Lijun, Bolland, Danielle E., Coffman, Lan G., Peterson, Luke F., Talpaz, Moshe, Neamati, Nouri, Buckanovich, Ronald J.

Volltext

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer von Sato-Kaneko, Fumi, Yao, Shiyin, Ahmadi, Alast, Zhang, Shannon S, Hosoya, Tadashi, Kaneda, Megan M, Varner, Judith A, Pu, Minya, Messer, Karen S, Guiducci, Cristiana, Coffman, Robert L, Kitaura, Kazutaka, Matsutani, Takaji, Suzuki, Ryuji, Carson, Dennis A, Hayashi, Tomoko, Cohen, Ezra Ew

Volltext

Implementation of a stepped wedge cluster randomized trial to evaluate a hospital mobility program von Hastings, Susan N, Stechuchak, Karen M, Choate, Ashley, Mahanna, Elizabeth P, Van Houtven, Courtney, Allen, Kelli D, Wang, Virginia, Sperber, Nina, Zullig, Leah, Bosworth, Hayden B, Coffman, Cynthia J

Volltext

Human carcinoma-associated mesenchymal stem cells promote ovarian cancer chemotherapy resistance via a BMP4/HH signaling loop von Coffman, Lan G, Choi, Yun-Jung, McLean, Karen, Allen, Benjamin L, di Magliano, Marina Pasca, Buckanovich, Ronald J

Volltext

Atypical variation within the deep gluteal region: A case report featuring double piriformis, non-forming sciatic nerve, and abnormal course of the gluteal vessels von Coffman-Rea, Kara, Arwood, Skylar, Samonds, Karen E.

Volltext

Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions von Marshall, Jason D., Fearon, Karen, Abbate, Christi, Subramanian, Sandhya, Yee, Priscilla, Gregorio, Josh, Coffman, Robert L., Van Nest, Gary

Volltext

A Second-Generation Oral SARS-CoV‑2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19 von Allerton, Charlotte M. N., Arcari, Joel T., Aschenbrenner, Lisa M., Avery, Melissa, Bechle, Bruce M., Behzadi, Mohammad Amin, Boras, Britton, Buzon, Leanne M., Cardin, Rhonda D., Catlin, Natasha R., Carlo, Anthony A., Coffman, Karen J., Dantonio, Alyssa, Di, Li, Eng, Heather, Farley, Kathleen A., Ferre, Rose Ann, Gernhardt, Steven S., Gibson, Scott A., Greasley, Samantha E., Greenfield, Siennah R., Hurst, Brett L., Kalgutkar, Amit S., Kimoto, Emi, Lanyon, Lorraine F., Lovett, Gabrielle H., Lian, Yajing, Liu, Wei, Martínez Alsina, Luis A., Noell, Stephen, Obach, R. Scott, Owen, Dafydd R., Patel, Nandini C., Rai, Devendra K., Reese, Matthew R., Rothan, Hussin A., Sakata, Sylvie, Sammons, Matthew F., Sathish, Jean G., Sharma, Raman, Steppan, Claire M., Tuttle, Jamison B., Verhoest, Patrick R., Wei, Liuqing, Yang, Qingyi, Yurgelonis, Irina, Zhu, Yuao

Volltext

Informing a home time measure reflective of quality of life: A data driven investigation of time frames and settings of health care utilization von Dennis, Paul A, Stechuchak, Karen M, Van Houtven, Courtney H, Decosimo, Kasey, Coffman, Cynthia J, Grubber, Janet M, Lindquist, Jennifer H, Sperber, Nina R, Hastings, S Nicole, Shepherd-Banigan, Megan, Kaufman, Brystana G, Smith, Valerie A

Volltext