From virotherapy to oncolytic immunotherapy: where are we now? von Coffin, Robert S

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Development of a new fusion-enhanced oncolytic immunotherapy platform based on herpes simplex virus type 1 von Thomas, Suzanne, Kuncheria, Linta, Roulstone, Victoria, Kyula, Joan N, Mansfield, David, Bommareddy, Praveen K, Smith, Henry, Kaufman, Howard L, Harrington, Kevin J, Coffin, Robert S

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White paper on microbial anti-cancer therapy and prevention von Forbes, Neil S, Coffin, Robert S, Deng, Liang, Evgin, Laura, Fiering, Steve, Giacalone, Matthew, Gravekamp, Claudia, Gulley, James L, Gunn, Hal, Hoffman, Robert M, Kaur, Balveen, Liu, Ke, Lyerly, Herbert Kim, Marciscano, Ariel E, Moradian, Eddie, Ruppel, Sheryl, Saltzman, Daniel A, Tattersall, Peter J, Thorne, Steve, Vile, Richard G, Zhang, Halle Huihong, Zhou, Shibin, McFadden, Grant

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Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury von Kitamura, Kazuya, Iwanami, Akio, Nakamura, Masaya, Yamane, Junichi, Watanabe, Kota, Suzuki, Yoshinori, Miyazawa, Daisuke, Shibata, Shinsuke, Funakoshi, Hiroshi, Miyatake, Shinichi, Coffin, Robert S., Nakamura, Toshikazu, Toyama, Yoshiaki, Okano, Hideyuki

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Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma von Andtbacka, Robert H I, Kaufman, Howard L, Collichio, Frances, Amatruda, Thomas, Senzer, Neil, Chesney, Jason, Delman, Keith A, Spitler, Lynn E, Puzanov, Igor, Agarwala, Sanjiv S, Milhem, Mohammed, Cranmer, Lee, Curti, Brendan, Lewis, Karl, Ross, Merrick, Guthrie, Troy, Linette, Gerald P, Daniels, Gregory A, Harrington, Kevin, Middleton, Mark R, Miller, Jr, Wilson H, Zager, Jonathan S, Ye, Yining, Yao, Bin, Li, Ai, Doleman, Susan, VanderWalde, Ari, Gansert, Jennifer, Coffin, Robert S

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Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer von Crespo-Rodriguez, Eva, Bergerhoff, Katharina, Bozhanova, Galabina, Foo, Shane, Patin, Emmanuel C, Whittock, Harriet, Buus, Richard, Haider, Syed, Muirhead, Gareth, Thway, Khin, Newbold, Kate, Coffin, Robert S, Vile, Richard G, Kim, Dae, McLaughlin, Martin, Melcher, Alan A, Harrington, Kevin J, Pedersen, Malin

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Herpes Simplex Virus Type 1 Induces CD83 Degradation in Mature Dendritic Cells with Immediate-Early Kinetics via the Cellular Proteasome von KUMMER, Mirko, TURZA, Nadine M, MUHL-ZURBES, Petra, LECHMANN, Matthias, BOUTELL, Chris, COFFIN, Robert S, EVERETT, Roger D, STEINKASSERER, Alexander, PRECHTEL, Alexander T

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Combination of a fusogenic glycoprotein, prodrug activation, and oncolytic herpes simplex virus for enhanced local tumor control von SIMPSON, Guy R, ZIQUN HAN, BINLEI LIU, YIBING WANG, CAMPBELL, Gregor, COFFIN, Robert S

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Herpes Simplex Virus Infection of Dendritic Cells: Balance among Activation, Inhibition, and Immunity von Pollara, Gabriele, Speidel, Katharina, Samady, Laila, Rajpopat, Mansi, McGrath, Yvonne, Ledermann, Jonathan, Coffin, Robert S., Katz, David R., Chain, Benjamin

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Deletion of the Virion Host Shutoff Protein (vhs) from Herpes Simplex Virus (HSV) Relieves the Viral Block to Dendritic Cell Activation: Potential of vhs− HSV Vectors for Dendritic... von Samady, Laila, Costigliola, Emanuela, MacCormac, Luci, McGrath, Yvonne, Cleverley, Steve, Lilley, Caroline E, Smith, Jill, Latchman, David S, Chain, Benny, Coffin, Robert S

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Herpes Simplex Virus Type-1-Induced Activation of Myeloid Dendritic Cells: The Roles of Virus Cell Interaction and Paracrine Type I IFN Secretion von Pollara, Gabriele, Jones, Meleri, Handley, Matthew E, Rajpopat, Mansi, Kwan, Antonia, Coffin, Robert S, Foster, Graham, Chain, Benjamin, Katz, David R

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Expression of RNA interference triggers from an oncolytic herpes simplex virus results in specific silencing in tumour cells in vitro and tumours in vivo von Anesti, Anna-Maria, Simpson, Guy R, Price, Toby, Pandha, Hardev S, Coffin, Robert S

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ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter von Hunt, David, Hossain-Ibrahim, Kismet, Mason, Matthew R J, Coffin, Robert S, Lieberman, A R, Winterbottom, Julia, Anderson, P N

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Novel Therapeutic Strategy for Stroke in Rats by Bone Marrow Stromal Cells and ex vivo HGF Gene Transfer with HSV-1 Vector von Zhao, Ming-Zhu, Nonoguchi, Naosuke, Ikeda, Naokado, Watanabe, Takuji, Furutama, Daisuke, Miyazawa, Daisuke, Funakoshi, Hiroshi, Kajimoto, Yoshinaga, Nakamura, Toshikazu, Dezawa, Mari, Shibata, Masa-Aki, Otsuki, Yoshinori, Coffin, Robert S, Liu, Wei-Dong, Kuroiwa, Toshihiko, Miyatake, Shin-Ichi

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VASCULAR ENDOTHELIAL GROWTH FACTOR GENE-TRANSFERRED BONE MARROW STROMAL CELLS ENGINEERED WITH A HERPES SIMPLEX VIRUS TYPE 1 VECTOR CAN IMPROVE NEUROLOGICAL DEFICITS AND REDUCE INFA... von Miki, Yoshihito, Nonoguchi, Naosuke, Ikeda, Naokado, Coffin, Robert S., Kuroiwa, Toshihiko, Miyatake, Shin-Ichi

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A Novel HSV-1 Virus, JS1/34.5−/47−, Purges Contaminating Breast Cancer Cells From Bone Marrow von HU, Jennifer C, BOOTH, Matthew J, COOMBES, R. Charles, KAMALATI, Tahereh, TRIPURANENI, Gopichand, DAVIES, Derek, ZAIDI, Syed A. A, DE BELLA, Manuelatamburo, SLADE, Martin J, MARLEY, Stephen B, GORDON, Myrtle Y. A, COFFIN, Robert S

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Bone marrow stromal cells that enhanced fibroblast growth factor-2 secretion by herpes simplex virus vector improve neurological outcome after transient focal cerebral ischemia in... von IKEDA, Naokado, NONOGUCHI, Naosuke, KUROIWA, Toshihiko, MIYATAKE, Shin-Ichi, MING ZHU ZHAO, WATANABE, Takuji, KAJIMOTO, Yoshinaga, FURUTAMA, Daisuke, KIMURA, Fumiharu, DEZAWA, Mari, COFFIN, Robert S, OTSUKI, Yoshinori

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705 Biodistribution and shedding analysis following RP1 oncolytic immunotherapy dosing in patients from the IGNYTE clinical trial von Bommareddy, Praveen K, Monteagudo, Alina, Milhem, Mohammed, Sacco, Joseph J, Bowles, Tawnya Lynn, Tsai, Katy K, In, Gino K, Muñoz-Couselo, Eva, VanderWalde, Ari M, Chesney, Jason Alan, Michels, Judith, Samson, Adel, Beasley, Georgia M, Wise-Draper, Trisha M, Schadendorf, Dirk, Mahmoud, Fade, Wong, Michael K, Hong, Walter, Hou, Jeannie W, Clack, Aaron, Coffin, Robert S, Middleton, Mark R, Chmielowski, Bartosz

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Impact of Process Conditions on the Centrifugal Recovery of a Disabled Herpes Simplex Virus von Lotfian, Pantea, Levy, M. Susana, Coffin, Robert. S., Fearn, T., Ayazi-Shamlou, Parviz

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Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus von Anesti, Anna-Maria, Peeters, Pieter J, Royaux, Ines, Coffin, Robert S

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