motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites von Coetzee, Simon G, Coetzee, Gerhard A, Hazelett, Dennis J

Volltext

Comprehensive functional annotation of 77 prostate cancer risk loci von Hazelett, Dennis J, Rhie, Suhn Kyong, Gaddis, Malaina, Yan, Chunli, Lakeland, Daniel L, Coetzee, Simon G, Henderson, Brian E, Noushmehr, Houtan, Cozen, Wendy, Kote-Jarai, Zsofia, Eeles, Rosalind A, Easton, Douglas F, Haiman, Christopher A, Lu, Wange, Farnham, Peggy J, Coetzee, Gerhard A

Volltext

ELMER v.2: an R/Bioconductor package to reconstruct gene regulatory networks from DNA methylation and transcriptome profiles von Silva, Tiago C, Coetzee, Simon G, Gull, Nicole, Yao, Lijing, Hazelett, Dennis J, Noushmehr, Houtan, Lin, De-Chen, Berman, Benjamin P

Volltext

Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes von Yáñez, Alberto, Coetzee, Simon G., Olsson, Andre, Muench, David E., Berman, Benjamin P., Hazelett, Dennis J., Salomonis, Nathan, Grimes, H. Leighton, Goodridge, Helen S.

Volltext

ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis von Rotinen, Mirja, You, Sungyong, Yang, Julie, Coetzee, Simon G., Reis-Sobreiro, Mariana, Huang, Wen-Chin, Huang, Fangjin, Pan, Xinlei, Yáñez, Alberto, Hazelett, Dennis J., Chu, Chia-Yi, Steadman, Kenneth, Morrissey, Colm M., Nelson, Peter S., Corey, Eva, Chung, Leland W. K., Freedland, Stephen J., Di Vizio, Dolores, Garraway, Isla P., Murali, Ramachandran, Knudsen, Beatrice S., Freeman, Michael R.

Volltext

Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells von Rhie, Suhn Kyong, Hazelett, Dennis J, Coetzee, Simon G, Yan, Chunli, Noushmehr, Houtan, Coetzee, Gerhard A

Volltext

Comprehensive functional annotation of seventy-one breast cancer risk Loci von Rhie, Suhn Kyong, Coetzee, Simon G, Noushmehr, Houtan, Yan, Chunli, Kim, Jae Mun, Haiman, Christopher A, Coetzee, Gerhard A

Volltext

FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs von Coetzee, Simon G, Rhie, Suhn K, Berman, Benjamin P, Coetzee, Gerhard A, Noushmehr, Houtan

Volltext

Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiology von Coetzee, Simon G., Pierce, Steven, Brundin, Patrik, Brundin, Lena, Hazelett, Dennis J., Coetzee, Gerhard A.

Volltext

GENAVi: a shiny web application for gene expression normalization, analysis and visualization von Reyes, Alberto Luiz P, Silva, Tiago C, Coetzee, Simon G, Plummer, Jasmine T, Davis, Brian D, Chen, Stephanie, Hazelett, Dennis J, Lawrenson, Kate, Berman, Benjamin P, Gayther, Simon A, Jones, Michelle R

Volltext

Diagnostic and therapeutic potential of RNASET2 in Crohn's disease: Disease-risk polymorphism modulates allelic-imbalance in expression and circulating protein levels and recombina... von Biener-Ramanujan, Eva, Rosier, Florian, Coetzee, Simon G, McGovern, Dermot D P, Hazelett, Dennis, Targan, Stephan R, Gonsky, Rivkah

Volltext

motifbreakR v2: expanded variant analysis including indels and integrated evidence from transcription factor binding databases von Coetzee, Simon G, Hazelett, Dennis J

Volltext

DNA methylation and transcriptomic features are preserved throughout disease recurrence and chemoresistance in high grade serous ovarian cancers von Gull, Nicole, Jones, Michelle R, Peng, Pei-Chen, Coetzee, Simon G, Silva, Tiago C, Plummer, Jasmine T, Reyes, Alberto Luiz P, Davis, Brian D, Chen, Stephanie S, Lawrenson, Kate, Lester, Jenny, Walsh, Christine, Rimel, Bobbie J, Li, Andrew J, Cass, Ilana, Berg, Yonatan, Govindavari, John-Paul B, Rutgers, Joanna K. L, Berman, Benjamin P, Karlan, Beth Y, Gayther, Simon A

Volltext

Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites von Jones, Michelle R., Peng, Pei-Chen, Coetzee, Simon G., Tyrer, Jonathan, Reyes, Alberto Luiz P., Corona, Rosario I., Davis, Brian, Chen, Stephanie, Dezem, Felipe, Seo, Ji-Heui, Kar, Siddartha, Dareng, Eileen, Berman, Benjamin P., Freedman, Matthew L., Plummer, Jasmine T., Lawrenson, Kate, Pharoah, Paul, Hazelett, Dennis J., Gayther, Simon A.

Volltext

A Study of High-Grade Serous Ovarian Cancer Origins Implicates the SOX18 Transcription Factor in Tumor Development von Lawrenson, Kate, Fonseca, Marcos A.S., Liu, Annie Y., Segato Dezem, Felipe, Lee, Janet M., Lin, Xianzhi, Corona, Rosario I., Abbasi, Forough, Vavra, Kevin C., Dinh, Huy Q., Gill, Navjot Kaur, Seo, Ji-Heui, Coetzee, Simon, Lin, Yvonne G., Pejovic, Tanja, Mhawech-Fauceglia, Paulette, Rowat, Amy C., Drapkin, Ronny, Karlan, Beth Y., Hazelett, Dennis J., Freedman, Matthew L., Gayther, Simon A., Noushmehr, Houtan

Volltext

A rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk von Hazelett, Dennis J., Coetzee, Simon G., Coetzee, Gerhard A.

Volltext

Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1 von Biancolella, Michela, Fortini, Barbara K, Tring, Stephanie, Plummer, Sarah J, Mendoza-Fandino, Gustavo A, Hartiala, Jaana, Hitchler, Michael J, Yan, Chunli, Schumacher, Fredrick R, Conti, David V, Edlund, Christopher K, Noushmehr, Houtan, Coetzee, Simon G, Bresalier, Robert S, Ahnen, Dennis J, Barry, Elizabeth L, Berman, Benjamin P, Rice, Judd C, Coetzee, Gerhard A, Casey, Graham

Volltext

A molecular taxonomy of tumors independent of tissue-of-origin von Nguyen, Peter T., Coetzee, Simon G., Lakeland, Daniel L., Hazelett, Dennis J.

Volltext

SIRT1 regulates Mxd1 during malignant melanoma progression von Meliso, Fabiana M, Micali, Danilo, Silva, Camila T, Sabedot, Thaís S, Coetzee, Simon G, Koch, Adrian, Fahlbusch, Fabian B, Noushmehr, Houtan, Schneider-Stock, Regine, Jasiulionis, Miriam G

Volltext

Interleukin-6-Related Genotypes, Body Mass Index, and Risk of Multiple Myeloma and Plasmacytoma von Cozen, Wendy, Gebregziabher, Mulugeta, Conti, David V, Van Den Berg, David J, Coetzee, Gerhard A, Wang, Sophia S, Rothman, Nathaniel, Bernstein, Leslie, Hartge, Patricia, Morhbacher, Ann, Coetzee, Simon G, Salam, Muhammad T, Wang, Wei, Zadnick, John, Ingles, Sue A

Volltext