Bromodomains: a new target class for drug development von Cochran, Andrea G., Conery, Andrew R., Sims, Robert J.

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A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications von Flynn, E. Megan, Huang, Oscar W., Poy, Florence, Oppikofer, Mariano, Bellon, Steve F., Tang, Yong, Cochran, Andrea G.

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GNE-235: A Lead Compound Selective for the Second Bromodomain of PBRM1 von Cochran, Andrea G., Flynn, Megan

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BMI1–RING1B is an autoinhibited RING E3 ubiquitin ligase von Taherbhoy, Asad M., Huang, Oscar W., Cochran, Andrea G.

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An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells von Vinogradova, Maia, Gehling, Victor S, Gustafson, Amy, Arora, Shilpi, Tindell, Charles A, Wilson, Catherine, Williamson, Kaylyn E, Guler, Gulfem D, Gangurde, Pranoti, Manieri, Wanda, Busby, Jennifer, Flynn, E Megan, Lan, Fei, Kim, Hyo-jin, Odate, Shobu, Cochran, Andrea G, Liu, Yichin, Wongchenko, Matthew, Yang, Yibin, Cheung, Tommy K, Maile, Tobias M, Lau, Ted, Costa, Michael, Hegde, Ganapati V, Jackson, Erica, Pitti, Robert, Arnott, David, Bailey, Christopher, Bellon, Steve, Cummings, Richard T, Albrecht, Brian K, Harmange, Jean-Christophe, Kiefer, James R, Trojer, Patrick, Classon, Marie

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Expansion of the ISWI chromatin remodeler family with new active complexes von Oppikofer, Mariano, Bai, Tianyi, Gan, Yutian, Haley, Benjamin, Liu, Peter, Sandoval, Wendy, Ciferri, Claudio, Cochran, Andrea G

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Wnt Antagonists Bind through a Short Peptide to the First β-Propeller Domain of LRP5/6 von Bourhis, Eric, Wang, Weiru, Tam, Christine, Hwang, Jiyoung, Zhang, Yingnan, Spittler, Didier, Huang, Oscar W., Gong, Yan, Estevez, Alberto, Zilberleyb, Inna, Rouge, Lionel, Chiu, Cecilia, Wu, Yan, Costa, Mike, Hannoush, Rami N., Franke, Yvonne, Cochran, Andrea G.

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Reconstitution of a Frizzled8·Wnt3a·LRP6 Signaling Complex Reveals Multiple Wnt and Dkk1 Binding Sites on LRP6 von Bourhis, Eric, Tam, Christine, Franke, Yvonne, Bazan, J. Fernando, Ernst, James, Hwang, Jiyoung, Costa, Mike, Cochran, Andrea G., Hannoush, Rami N.

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Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex von Bentley, Matthew L, Corn, Jacob E, Dong, Ken C, Phung, Qui, Cheung, Tommy K, Cochran, Andrea G

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Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300 von Crawford, Terry D, Romero, F. Anthony, Lai, Kwong Wah, Tsui, Vickie, Taylor, Alexander M, de Leon Boenig, Gladys, Noland, Cameron L, Murray, Jeremy, Ly, Justin, Choo, Edna F, Hunsaker, Thomas L, Chan, Emily W, Merchant, Mark, Kharbanda, Samir, Gascoigne, Karen E, Kaufman, Susan, Beresini, Maureen H, Liao, Jiangpeng, Liu, Wenfeng, Chen, Kevin X, Chen, Zhongguo, Conery, Andrew R, Côté, Alexandre, Jayaram, Hariharan, Jiang, Ying, Kiefer, James R, Kleinheinz, Tracy, Li, Yingjie, Maher, Jonathan, Pardo, Eneida, Poy, Florence, Spillane, Kerry L, Wang, Fei, Wang, Jian, Wei, Xiaocang, Xu, Zhaowu, Xu, Zhongya, Yen, Ivana, Zawadzke, Laura, Zhu, Xiaoyu, Bellon, Steven, Cummings, Richard, Cochran, Andrea G, Albrecht, Brian K, Magnuson, Steven

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Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6 von Bourhis, Eric, Tam, Christine, Franke, Yvonne, Bazan, J Fernando, Ernst, James, Hwang, Jiyoung, Costa, Mike, Cochran, Andrea G, Hannoush, Rami N

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Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells von Rutz, Sascha, Kayagaki, Nobuhiko, Phung, Qui T., Eidenschenk, Celine, Noubade, Rajkumar, Wang, Xiaoting, Lesch, Justin, Lu, Rongze, Newton, Kim, Huang, Oscar W., Cochran, Andrea G., Vasser, Mark, Fauber, Benjamin P., DeVoss, Jason, Webster, Joshua, Diehl, Lauri, Modrusan, Zora, Kirkpatrick, Donald S., Lill, Jennie R., Ouyang, Wenjun, Dixit, Vishva M.

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Non-canonical reader modules of BAZ1A promote recovery from DNA damage von Oppikofer, Mariano, Sagolla, Meredith, Haley, Benjamin, Zhang, Hui-Min, Kummerfeld, Sarah K., Sudhamsu, Jawahar, Flynn, E. Megan, Bai, Tianyi, Zhang, Jennifer, Ciferri, Claudio, Cochran, Andrea G.

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Tryptophan Zippers: Stable, Monomeric β-Hairpins von Cochran, Andrea G., Skelton, Nicholas J., Starovasnik, Melissa A.

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Trifluoroacetyl Lysine as a Bromodomain Binding Mimic of Lysine Acetylation von Miller, Gregory M., Flynn, E. Megan, Tom, Jeffrey, Song, Aimin, Cochran, Andrea G.

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Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains von Crawford, Terry D, Tsui, Vickie, Flynn, E. Megan, Wang, Shumei, Taylor, Alexander M, Côté, Alexandre, Audia, James E, Beresini, Maureen H, Burdick, Daniel J, Cummings, Richard, Dakin, Les A, Duplessis, Martin, Good, Andrew C, Hewitt, Michael C, Huang, Hon-Ren, Jayaram, Hariharan, Kiefer, James R, Jiang, Ying, Murray, Jeremy, Nasveschuk, Christopher G, Pardo, Eneida, Poy, Florence, Romero, F. Anthony, Tang, Yong, Wang, Jian, Xu, Zhaowu, Zawadzke, Laura E, Zhu, Xiaoyu, Albrecht, Brian K, Magnuson, Steven R, Bellon, Steve, Cochran, Andrea G

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1 von Taylor, Alexander M., Bailey, Chris, Belmont, Lisa D., Campbell, Robert, Cantone, Nico, Côté, Alexandre, Crawford, Terry D., Cummings, Richard, DeMent, Kevin, Duplessis, Martin, Flynn, Megan, Good, Andrew C., Huang, Hon-Ren, Joshi, Shivangi, Leblanc, Yves, Murray, Jeremy, Nasveschuk, Christopher G., Neiss, Adrianne, Poy, Florence, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Tsui, Vickie, Zawadzke, Laura, Sims, Robert J., Audia, James E., Bellon, Steven F., Magnuson, Steven R., Albrecht, Brian K., Cochran, Andrea G.

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Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance von Crawford, Terry D., Vartanian, Steffan, Côté, Alexandre, Bellon, Steve, Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael, Huang, Hon-Ren, Kiefer, James R., Murray, Jeremy, Nasveschuk, Christopher G., Pardo, Eneida, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Taylor, Alexander M., Tsui, Vickie, Wang, Jian, Wang, Shumei, Zawadzke, Laura, Albrecht, Brian K., Magnuson, Steven R., Cochran, Andrea G., Stokoe, David

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Regulation of deubiquitinase proteolytic activity von Huang, Oscar W, Cochran, Andrea G

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Phosphorylation-dependent activity of the deubiquitinase DUBA von Huang, Oscar W, Ma, Xiaolei, Yin, JianPing, Flinders, Jeremy, Maurer, Till, Kayagaki, Nobuhiko, Phung, Qui, Bosanac, Ivan, Arnott, David, Dixit, Vishva M, Hymowitz, Sarah G, Starovasnik, Melissa A, Cochran, Andrea G

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