Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizu... von Tabernero, Josep, Dr, Yoshino, Takayuki, MD, Cohn, Allen Lee, MD, Obermannova, Radka, MD, Bodoky, Gyorgy, Prof, Garcia-Carbonero, Rocio, MD, Ciuleanu, Tudor-Eliade, Prof, Portnoy, David C, MD, Van Cutsem, Eric, Prof, Grothey, Axel, MD, Prausová, Jana, MD, Garcia-Alfonso, Pilar, PhD, Yamazaki, Kentaro, MD, Clingan, Philip R, Prof, Lonardi, Sara, MD, Kim, Tae Won, Prof, Simms, Lorinda, MS, Chang, Shao-Chun, PhD, Nasroulah, Federico, MD

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Updated Analysis From KEYNOTE-189: Pembrolizumab or Placebo Plus Pemetrexed and Platinum for Previously Untreated Metastatic Nonsquamous Non-Small-Cell Lung Cancer von Gadgeel, Shirish, Rodríguez-Abreu, Delvys, Speranza, Giovanna, Esteban, Emilio, Felip, Enriqueta, Dómine, Manuel, Hui, Rina, Hochmair, Maximilian J, Clingan, Philip, Powell, Steven F, Cheng, Susanna Yee-Shan, Bischoff, Helge G, Peled, Nir, Grossi, Francesco, Jennens, Ross R, Reck, Martin, Garon, Edward B, Novello, Silvia, Rubio-Viqueira, Belén, Boyer, Michael, Kurata, Takayasu, Gray, Jhanelle E, Yang, Jing, Bas, Tuba, Pietanza, M Catherine, Garassino, Marina C

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Improved Overall Survival With Oxaliplatin, Fluorouracil, and Leucovorin As Adjuvant Treatment in Stage II or III Colon Cancer in the MOSAIC Trial von ANDRE, Thierry, BONI, Corrado, DE GRAMONT, Aimery, NAVARRO, Matilde, TABERNERO, Josep, HICKISH, Tamas, TOPHAM, Clare, BONETTI, Andrea, CLINGAN, Philip, BRIDGEWATER, John, RIVERA, Fernando

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Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer von André, Thierry, Boni, Corrado, Mounedji-Boudiaf, Lamia, Navarro, Matilde, Tabernero, Josep, Hickish, Tamas, Topham, Clare, Zaninelli, Marta, Clingan, Philip, Bridgewater, John, Tabah-Fisch, Isabelle, de Gramont, Aimery

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Pembrolizumab with platinum-based chemotherapy with or without epacadostat as first-line treatment for metastatic non-small cell lung cancer: a randomized, partially double-blind,... von Boyer, Michael, Hui, Rina, Urban, Damien, Clingan, Philip, Su, Wu-Chou, Devaux, Celine, Gadgeel, Shirish, Garassino, Marina, Leopold, Lance, Daniel, Jeannie, Munteanu, Mihaela C, Samkari, Ayman, Luo, Yiwen, Abreu, Delvys Rodriguez

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Sidedness is prognostic in locoregional colon cancer: an analysis of 9509 Australian patients von Brungs, Daniel, Aghmesheh, Morteza, de Souza, Paul, Ng, Weng, Chua, Wei, Carolan, Martin, Clingan, Philip, Healey, Emma, Rose, June, Tubaro, Tameika, Ranson, Marie

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A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy von Kefford, Richard F, Clingan, Philip R, Brady, Benjamin, Ballmer, Andrea, Morganti, Adele, Hersey, Peter

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Exposure–response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial von Cohn, Allen Lee, Yoshino, Takayuki, Heinemann, Volker, Obermannova, Radka, Bodoky, György, Prausová, Jana, Garcia-Carbonero, Rocio, Ciuleanu, Tudor, Garcia-Alfonso, Pilar, Portnoy, David C., Van Cutsem, Eric, Yamazaki, Kentaro, Clingan, Philip R., Polikoff, Jonathon, Lonardi, Sara, O’Brien, Lisa M., Gao, Ling, Yang, Ling, Ferry, David, Nasroulah, Federico, Tabernero, Josep

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A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED) von Prasanna, Thiru, Malik, Laeeq, McCuaig, Robert D., Tu, Wen Juan, Wu, Fan, Lim, Pek Siew, Tan, Abel H. Y., Dahlstrom, Jane E., Clingan, Philip, Moylan, Eugene, Chrisp, Jeremy, Fuller, David, Rao, Sudha, Yip, Desmond

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Evidence for the evolving role of neoadjuvant and perioperative immunotherapy in resectable non-small cell lung cancer von Hansen, Thomas, Hill, Jonathon, Tincknell, Gary, Siu, Derrick, Brungs, Daniel, Clingan, Philip, Chantrill, Lorraine, Nindra, Udit

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Immune checkpoint inhibitor-induced myocarditis, myositis, myasthenia gravis and transaminitis: a case series and review von Wai Siu, Derrick Ho, O’Neill, Robert Sean, Harris, Carole A, Wang, Justine, Ardolino, Luke, Downton, Teesha, Tong, Matthew, Hong, Jun Hee, Chin, Venessa, Clingan, Philip R, Aghmesheh, Morteza, Soudy, Hussein

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Clinical and molecular profile of young adults with early‐onset colorectal cancer: Experience from four Australian tertiary centers von Siu, Derrick Ho Wai, Ali, Arwa, Tjokrowidjaja, Angelina, De Silva, Madhawa, Lee, Joanna, Clingan, Philip R., Aghmesheh, Morteza, Brungs, Daniel, Mapagu, Cristina, Goldstein, David, O'Neill, Siobhan, Liauw, Winston S., Sjoquist, Katrin M., Thomas, David, Pavlakis, Nick, Clarke, Stephen J., Diakos, Connie, Chantrill, Lorraine A.

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Efficacy and safety of cosibelimab, an anti-PD-L1 antibody, in metastatic cutaneous squamous cell carcinoma von Clingan, Philip, Ladwa, Rahul, Brungs, Daniel, Harris, Dean Laurence, McGrath, Margaret, Arnold, Susan, Coward, Jermaine, Fourie, Samuel, Kurochkin, Andriy, Malan, Daniel R, Mant, Andrew, Sharma, Vinay, Shue, Hong, Tazbirkova, Andrea, Berciano-Guerrero, Miguel-Angel, Charoentum, Chaiyut, Dalle, Stéphane, Dechaphunkul, Arunee, Dudnichenko, Oleksandr, Koralewski, Piotr, Lugowska, Iwona, Montaudié, Henri, Muñoz-Couselo, Eva, Sriuranpong, Virote, Oliviero, James, Desai, Jayesh

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Polypyrrole stretchable actuators von Zheng, Wen, Alici, Gursel, Clingan, Philip R., Munro, Bridget J., Spinks, Geoffrey M., Steele, Julie R., Wallace, Gordon G.

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Comparative effectiveness of 5-fluorouracil with and without oxaliplatin in the treatment of colorectal cancer in clinical practice von Healey, Emma, Stillfried, Gillian E, Eckermann, Simon, Dawber, James P, Clingan, Philip R, Ranson, Marie

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Are BRAF mutated metastatic colorectal cancer (mCRC) tumors more responsive to VEGFR-2 blockage? Analysis of patient outcomes by RAS/RAF mutation status in the RAISE study—A global... von Yoshino, Takayuki, Obermannova, Radka, Bodoky, Gyorgy, Prausová, Jana, Garcia-Carbonero, Rocio, Ciuleanu, Tudor-Eliade, Garcia Alfonso, Pilar, Portnoy, David Craig, Cohn, Allen Lee, Van Cutsem, Eric, Yamazaki, Kentaro, Clingan, Philip, Muro, Kei, Kim, Tae Won, Wijayawardana, Sameera R., Hozak, Rebecca, Nasroulah, Federico, Tabernero, Josep

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Abstract CT075: KEYNOTE-189: Randomized, double-blind, phase 3 study of pembrolizumab (pembro) or placebo plus pemetrexed (pem) and platinum as first-line therapy for metastatic NS... von Gandhi, Leena, Rodgríguez-Abreu, Delvys, Gadgeel, Shirish, Esteban, Emilio, Felip, Enriqueta, Angelis, Flávia De, Domine, Manuel, Clingan, Philip, Hochmair, Maximilian J, Powell, Steven, Cheng, Susanna Yee-Shan, Bischoff, Helge G, Peled, Nir, Grossi, Francesco, Jennens, Ross R, Reck, Martin, Hui, Rina, Garon, Edward B, Boyer, Michael, Rubio-Viqueira, Belén, Novello, Silvia, Kurata, Takayasu, Gray, Jhanelle E, Vida, John J, Wei, Ziwen, Yang, Jing, Raftopoulos, Harry, Pietanza, M. Catherine, Garassino, Marina C

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First‐in‐human phase I study of infusional and bolus schedules of Deflexifol, a novel 5‐fluorouracil and leucovorin formulation, after failure of standard treatment von Clingan, Philip R., Ackland, Stephen P., Brungs, Daniel, Souza, Paul, Aghmesheh, Morteza, Garg, Madhu B., Ranson, Richard D., Parker, Suzanne, Jokela, Rebecca, Ranson, Marie

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Hyaluronan-Irinotecan improves progression-free survival in 5-fluorouracil refractory patients with metastatic colorectal cancer: a randomized phase II trial von Gibbs, Peter, Clingan, Philip R, Ganju, Vinod, Strickland, Andrew H, Wong, Shirley S, Tebbutt, Niall C, Underhill, Craig R, Fox, Richard M, Clavant, Steven P, Leung, Jenny, Pho, Minh, Brown, Tracey J

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A phase 2 study of tasisulam sodium (LY573636 sodium) as second‐line treatment for patients with unresectable or metastatic melanoma von Kirkwood, John M., Gonzalez, Rene, Reintgen, Douglas, Clingan, Philip R., McWilliams, Robert R., de Alwis, Dinesh P., Zimmermann, Annamaria, Brown, Michael P., Ilaria, Robert L., Millward, Michael J.

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