Targeting lactate metabolism for cancer therapeutics von Doherty, Joanne R, Cleveland, John L

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Systems analysis of intracellular pH vulnerabilities for cancer therapy von Persi, Erez, Duran-Frigola, Miquel, Damaghi, Mehdi, Roush, William R., Aloy, Patrick, Cleveland, John L., Gillies, Robert J., Ruppin, Eytan

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Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury von Yurdagul, Arif, Subramanian, Manikandan, Wang, Xiaobo, Crown, Scott B., Ilkayeva, Olga R., Darville, Lancia, Kolluru, Gopi K., Rymond, Christina C., Gerlach, Brennan D., Zheng, Ze, Kuriakose, George, Kevil, Christopher G., Koomen, John M., Cleveland, John L., Muoio, Deborah M., Tabas, Ira

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The Many Faces of Hypusinated eIF5A: Cell Context-Specific Effects of the Hypusine Circuit and Implications for Human Health von Nakanishi, Shima, Cleveland, John L

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TP53 mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotype von Sallman, David A., McLemore, Amy F., Aldrich, Amy L., Komrokji, Rami S., McGraw, Kathy L., Dhawan, Abhishek, Geyer, Susan, Hou, Hsin-An, Eksioglu, Erika A., Sullivan, Amy, Warren, Sarah, MacBeth, Kyle J., Meggendorfer, Manja, Haferlach, Torsten, Boettcher, Steffen, Ebert, Benjamin L., Al Ali, Najla H., Lancet, Jeffrey E., Cleveland, John L., Padron, Eric, List, Alan F.

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The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype von Basiorka, Ashley A., McGraw, Kathy L., Eksioglu, Erika A., Chen, Xianghong, Johnson, Joseph, Zhang, Ling, Zhang, Qing, Irvine, Brittany A., Cluzeau, Thomas, Sallman, David A., Padron, Eric, Komrokji, Rami, Sokol, Lubomir, Coll, Rebecca C., Robertson, Avril A.B., Cooper, Matthew A., Cleveland, John L., O'Neill, Luke A., Wei, Sheng, List, Alan F.

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Lactate Wreaks Havoc on Tumor-Infiltrating T and NK Cells von Scott, Kristen E.N., Cleveland, John L.

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Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications von Hardbower, Dana M., Asim, Mohammad, Luis, Paula B., Singh, Kshipra, Barry, Daniel P., Yang, Chunying, Steeves, Meredith A., Cleveland, John L., Schneider, Claus, Piazuelo, M. Blanca, Gobert, Alain P., Wilson, Keith T.

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Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling von Sierra, Johanna C., Piazuelo, M. Blanca, Luis, Paula B., Barry, Daniel P., Allaman, Margaret M., Asim, Mohammad, Sebrell, Thomas A., Finley, Jordan L., Rose, Kristie L., Hill, Salisha, Holshouser, Steven L., Casero, Robert A., Cleveland, John L., Woster, Patrick M., Schey, Kevin L., Bimczok, Diane, Schneider, Claus, Gobert, Alain P., Wilson, Keith T.

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Mitochondrial dysfunction in ataxia-telangiectasia von Valentin-Vega, Yasmine A., MacLean, Kirsteen H., Tait-Mulder, Jacqueline, Milasta, Sandra, Steeves, Meredith, Dorsey, Frank C., Cleveland, John L., Green, Douglas R., Kastan, Michael B.

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Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis von Schaub, Franz X, Reza, Md Shamim, Flaveny, Colin A, Li, Weimin, Musicant, Adele M, Hoxha, Sany, Guo, Min, Cleveland, John L, Amelio, Antonio L

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Polyamine Homeostasis in Development and Disease von Nakanishi, Shima, Cleveland, John L

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Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis von DOHERTY, Joanne R, CHUNYING YANG, TORTOSA, Mariola, GENAU, Heide Marika, ROUNBEHLER, Robert J, YUNQI LU, DANG, Chi V, KUMAR, K. Ganesh, BUTLER, Andrew A, BANNISTER, Thomas D, HOOPER, Andrea T, UNSAL-KACMAZ, Keziban, SCOTT, Kristen E. N, ROUSH, William R, CLEVELAND, John L, CAMERON, Michael D, FALLAHI, Mohammad, WEIMIN LI, HALL, Mark A, AMELIO, Antonio L, MISHRA, Jitendra K, FANGZHENG LI

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Tristetraprolin Impairs Myc-Induced Lymphoma and Abolishes the Malignant State von Rounbehler, Robert J., Fallahi, Mohammad, Yang, Chunying, Steeves, Meredith A., Li, Weimin, Doherty, Joanne R., Schaub, Franz X., Sanduja, Sandhya, Dixon, Dan A., Blackshear, Perry J., Cleveland, John L.

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NIX is required for programmed mitochondrial clearance during reticulocyte maturation von Schweers, Rachel L, Zhang, Ji, Randall, Mindy S, Loyd, Melanie R, Li, Weimin, Dorsey, Frank C, Kundu, Mondira, Opferman, Joseph T, Cleveland, John L, Miller, Jeffery L, Ney, Paul A

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Role of Polyamines in Immune Cell Functions von Hesterberg, Rebecca S, Cleveland, John L, Epling-Burnette, Pearlie K

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Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance von Carew, Jennifer S., Nawrocki, Steffan T., Kahue, Charissa N., Zhang, Hui, Yang, Chunying, Chung, Linda, Houghton, Janet A., Huang, Peng, Giles, Francis J., Cleveland, John L.

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Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy von Joo, Joung Hyuck, Dorsey, Frank C., Joshi, Aashish, Hennessy-Walters, Kristin M., Rose, Kristie L., McCastlain, Kelly, Zhang, Ji, Iyengar, Rekha, Jung, Chang Hwa, Suen, Der-Fen, Steeves, Meredith A., Yang, Chia-Ying, Prater, Stephanie M., Kim, Do-Hyung, Thompson, Craig B., Youle, Richard J., Ney, Paul A., Cleveland, John L., Kundu, Mondira

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CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin von Fallahi, Mohammad, Amelio, Antonio L, Cleveland, John L, Rounbehler, Robert J

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Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation von Zhang, Ji, Randall, Mindy S., Loyd, Melanie R., Dorsey, Frank C., Kundu, Mondira, Cleveland, John L., Ney, Paul A.

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