Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors: effects of 5-amido- and 5-sulphonamido-indolyl groups on pharmacokinetics and hERG binding von Fraley, Mark E., Arrington, Kenneth L., Buser, Carolyn A., Ciecko, Patrice A., Coll, Kathleen E., Fernandes, Christine, Hartman, George D., Hoffman, William F., Lynch, Joseph J., McFall, Rosemary C., Rickert, Keith, Singh, Romi, Smith, Sheri, Thomas, Kenneth A., Wong, Bradley K.

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Potent 2-[(pyrimidin-4-yl)amine}-1,3-thiazole-5-carbonitrile-based inhibitors of VEGFR-2 (KDR) kinase von Sisko, John T., Tucker, Thomas J., Bilodeau, Mark T., Buser, Carolyn A., Ciecko, Patrice A., Coll, Kathleen E., Fernandes, Christine, Gibbs, Jackson B., Koester, Timothy J., Kohl, Nancy, Lynch, Joseph J., Mao, Xianzhi, McLoughlin, Debra, Miller-Stein, Cynthia M., Rodman, Leonard D., Rickert, Keith W., Sepp-Lorenzino, Laura, Shipman, Jennifer M., Thomas, Kenneth A., Wong, Bradley K., Hartman, George D.

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Design and synthesis of 1,5-diarylbenzimidazoles as inhibitors of the VEGF-receptor KDR von Bilodeau, Mark T., Cunningham, April M., Koester, Timothy J., Ciecko, Patrice A., Coll, Kathleen E., Huckle, William R., Hungate, Randall W., Kendall, Richard L., McFall, Rosemary C., Mao, Xianzhi, Rutledge, Ruth Z., Thomas, Kenneth A.

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A novel orally bioavailable inhibitor of kinase insert domain-containing receptor induces antiangiogenic effects and prevents tumor growth in vivo von SEPP-LORENZINO, Laura, RANDS, Elaine, COLL, Kathleen, CIECKO, Patrice, FRALEY, Mark, HOFFMAN, William, HARTMAN, George, HEIMBROOK, David, GIBBS, Jackson, KOHL, Nancy, THOMAS, Kenneth, XIANZHI MAO, CONNOLLY, Brett, SHIPMAN, Jennifer, ANTANAVAGE, Joanne, HILL, Susan, DAVIS, Lenora, BECK, Stephen, RICKERT, Keith

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Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors von Fraley, Mark E., Arrington, Kenneth L., Buser, Carolyn A., Ciecko, Patrice A., Coll, Kathleen E., Fernandes, Christine, Hartman, George D., Hoffman, William F., Lynch, Joseph J., McFall, Rosemary C., Rickert, Keith, Singh, Romi, Smith, Sheri, Thomas, Kenneth A., Wong, Bradley K.

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