p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling von Memmi, Elisa Maria, Sanarico, Anna Giulia, Giacobbe, Arianna, Peschiaroli, Angelo, Frezza, Valentina, Cicalese, Angelo, Pisati, Federica, Tosoni, Daniela, Zhou, Huiqing, Tonon, Giovanni, Antonov, Alexey, Melino, Gerry, Pelicci, Pier Giuseppe, Bernassola, Francesca

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DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions von Insinga, Alessandra, Cicalese, Angelo, Faretta, Mario, Gallo, Barbara, Albano, Luisa, Ronzoni, Simona, Furia, Laura, Viale, Andrea, Pelicci, Pier Giuseppe

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In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype von Bossi, Daniela, Cicalese, Angelo, Dellino, Gaetano I, Luzi, Lucilla, Riva, Laura, D'Alesio, Carolina, Diaferia, Giuseppe R, Carugo, Alessandro, Cavallaro, Elena, Piccioni, Rossana, Barberis, Massimo, Mazzarol, Giovanni, Testori, Alessandro, Punzi, Simona, Pallavicini, Isabella, Tosti, Giulio, Giacó, Luciano, Melloni, Giorgio, Heffernan, Timothy P, Natoli, Gioacchino, Draetta, Giulio F, Minucci, Saverio, Pelicci, PierGiuseppe, Lanfrancone, Luisa

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A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis von TRINEI, Mirella, GIORGIO, Marco, PETRONILLI, Valeria, MINUCCI, Saverio, BERNARDI, Paolo, LANFRANCONE, Luisa, PELICCI, Pier Giuseppe, CICALESE, Angelo, BAROZZI, Sara, VENTURA, Andrea, MIGLIACCIO, Enrica, MILIA, Elisabetta, PADURA, Ines Martin, RAKER, Veronica A, MACCARANA, Marco

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DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization von Di Micco, Raffaella, Cicalese, Angelo, Fumagalli, Marzia, Dobreva, Miryana, Verrecchia, Alessandro, Pelicci, Pier Giuseppe, di Fagagna, Fabrizio d'Adda

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The emerging role of p53 in stem cells von Bonizzi, Giuseppina, Cicalese, Angelo, Insinga, Alessandra, Pelicci, Pier Giuseppe

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DNA damage response in adult stem cells von Insinga, Alessandra, Cicalese, Angelo, Pelicci, Pier Giuseppe

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication von d'Adda di Fagagna, Fabrizio, Di Micco, Raffaella, Fumagalli, Marzia, Cicalese, Angelo, Piccinin, Sara, Gasparini, Patrizia, Luise, Chiara, Schurra, Catherine, Garre', Massimiliano, Giovanni Nuciforo, Paolo, Bensimon, Aaron, Maestro, Roberta, Giuseppe Pelicci, Pier

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In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer von Carugo, Alessandro, Genovese, Giannicola, Seth, Sahil, Nezi, Luigi, Rose, Johnathon Lynn, Bossi, Daniela, Cicalese, Angelo, Shah, Parantu Krushnakant, Viale, Andrea, Pettazzoni, Piergiorgio Francesco, Akdemir, Kadir Caner, Bristow, Christopher Aaron, Robinson, Frederick Scott, Tepper, James, Sanchez, Nora, Gupta, Sonal, Estecio, Marcos Roberto, Giuliani, Virginia, Dellino, Gaetano Ivan, Riva, Laura, Yao, Wantong, Di Francesco, Maria Emilia, Green, Tessa, D’Alesio, Carolina, Corti, Denise, Kang, Ya’an, Jones, Philip, Wang, Huamin, Fleming, Jason Bates, Maitra, Anirban, Pelicci, Pier Giuseppe, Chin, Lynda, DePinho, Ronald Anthony, Lanfrancone, Luisa, Heffernan, Timothy Paul, Draetta, Giulio Francesco

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RNAi screens identify CHD4 as an essential gene in breast cancer growth von D'Alesio, Carolina, Punzi, Simona, Cicalese, Angelo, Fornasari, Lorenzo, Furia, Laura, Riva, Laura, Carugo, Alessandro, Curigliano, Giuseppe, Criscitiello, Carmen, Pruneri, Giancarlo, Pelicci, Pier Giuseppe, Faretta, Mario, Bossi, Daniela, Lanfrancone, Luisa

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The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells von Cicalese, Angelo, Bonizzi, Giuseppina, Pasi, Cristina E., Faretta, Mario, Ronzoni, Simona, Giulini, Barbara, Brisken, Cathrin, Minucci, Saverio, Di Fiore, Pier Paolo, Pelicci, Pier Giuseppe

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A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis von Trinei, M, Giorgio, M, Cicalese, A, Barozzi, S, Ventura, A, Migliaccio, E, Milia, E, Padura, I M, Raker, V A, Maccarana, M, Petronilli, V, Minucci, S, Bernardi, P, Lanfrancone, L, Pelicci, P G

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Abstract B43: PILOT: a patient-oriented in vivo functional platform to identify new lethalities and optimize cancer treatment von Carugo, Alessandro, Genovese, Giannicola, Seth, Sahil, Nezi, Luigi, Cicalese, Angelo, Bossi, Daniela, Rose, Johnathon L., Viale, Andrea, Lanfrancone, Luisa, Heffernan, Timothy P., Draetta, Giulio F.

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Abstract A28: Challenging new epigenetic vulnerabilities in human metastatic melanoma PDXs von Bossi, Daniela, Cicalese, Angelo, Dellino, Ivan Gaetano, Luzi, Lucilla, Punzi, Simona, D'Alesio, Carolina, Cavallaro, Elena, Minucci, Saverio, Pelicci, PierGiuseppe, Lanfrancone, Luisa

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Abstract 1701: Identification of epigenetic modifiers able to suppress growth of pancreatic ductal adenocarcinoma: A patient-oriented in vivo functional platform von Carugo, Alessandro, Genovese, Giannicola, Seth, Sahil, Nezi, Luigi, Rose, Johnathon L., Viale, Andrea, Pettazzoni, Piergiorgio F., Cicalese, Angelo, Bossi, Daniela, Yao, Wantong, Fleming, Jason B., Lanfrancone, Luisa, Heffernan, Timothy P., Draetta, Giulio F.

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Precision Photometer Heads as Primary Transducers in Devices Used to Measure Luminous Quantities von Ivanov, V S, Kotyuk, A F, Sapritskii, V I, Stolyarevskaya, R I

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The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells von Cicalese, Angelo, Bonizzi, Giuseppina, Pasi, Christina, Faretta, Mario, Ronzoni, Simona, Giulini, Barbara, Brisken, Cathrin, Minucci, Saverio, Di Fiore, Pier Paolo, Pelicci, Pier Giuseppe

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Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial von Sessa, Maria, MD, Lorioli, Laura, MD, Fumagalli, Francesca, MD, Acquati, Serena, PhD, Redaelli, Daniela, MSc, Baldoli, Cristina, MD, Canale, Sabrina, MSc, Lopez, Ignazio D, MD, Morena, Francesco, PhD, Calabria, Andrea, PhD, Fiori, Rossana, MD, Silvani, Paolo, MD, Rancoita, Paola M V, PhD, Gabaldo, Michela, MSc, Benedicenti, Fabrizio, MSc, Antonioli, Gigliola, RN, Assanelli, Andrea, MD, Cicalese, Maria Pia, MD, del Carro, Ubaldo, MD, Sora, Maria Grazia Natali, MD, Martino, Sabata, PhD, Quattrini, Angelo, MD, Montini, Eugenio, PhD, Di Serio, Clelia, Prof, Ciceri, Fabio, MD, Roncarolo, Maria Grazia, Prof, Aiuti, Alessandro, MD, Naldini, Luigi, Prof, Biffi, Alessandra, Dr

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T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency von Brigida, Immacolata, Zoccolillo, Matteo, Cicalese, Maria Pia, Pfajfer, Laurène, Barzaghi, Federica, Scala, Serena, Oleaga-Quintas, Carmen, Álvarez-Álvarez, Jesus A., Sereni, Lucia, Giannelli, Stefania, Sartirana, Claudia, Dionisio, Francesca, Pavesi, Luca, Benavides-Nieto, Marta, Basso-Ricci, Luca, Capasso, Paola, Mazzi, Benedetta, Rosain, Jeremie, Marcus, Nufar, Lee, Yu Nee, Somech, Raz, Degano, Massimo, Raiola, Giuseppe, Caorsi, Roberta, Picco, Paolo, Moncada Velez, Marcela, Khourieh, Joelle, Arias, Andrés Augusto, Bousfiha, Aziz, Issekutz, Thomas, Issekutz, Andrew, Boisson, Bertrand, Dobbs, Kerry, Villa, Anna, Lombardo, Angelo, Neven, Benedicte, Moshous, Despina, Casanova, Jean-Laurent, Franco, José Luis, Notarangelo, Luigi D., Scielzo, Cristina, Volpi, Stefano, Dupré, Loïc, Bustamante, Jacinta, Gattorno, Marco, Aiuti, Alessandro

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The Impact of SARS-CoV-2 Infection in Patients with Inborn Errors of Immunity: the Experience of the Italian Primary Immunodeficiencies Network (IPINet) von Giardino, Giuliana, Milito, Cinzia, Lougaris, Vassilios, Punziano, Alessandra, Carrabba, Maria, Cinetto, Francesco, Scarpa, Riccardo, Dellepiane, Rosa Maria, Ricci, Silvia, Rivalta, Beatrice, Conti, Francesca, Marzollo, Antonio, Firinu, Davide, Cirillo, Emilia, Lagnese, Gianluca, Cancrini, Caterina, Martire, Baldassare, Danieli, Maria Giovanna, Pession, Andrea, Vacca, Angelo, Azzari, Chiara, Fabio, Giovanna, Soresina, Annarosa, Agostini, Carlo, Spadaro, Giuseppe, Badolato, Raffaele, Cicalese, Maria Pia, Aiuti, Alessandro, Plebani, Alessandro, Quinti, Isabella, Pignata, Claudio

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