Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates von Foster, Donald J., Brown, Christopher R., Shaikh, Sarfraz, Trapp, Casey, Schlegel, Mark K., Qian, Kun, Sehgal, Alfica, Rajeev, Kallanthottathil G., Jadhav, Vasant, Manoharan, Muthiah, Kuchimanchi, Satya, Maier, Martin A., Milstein, Stuart

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Linking stochastic fluctuations in chromatin structure and gene expression von Brown, Christopher R, Mao, Changhui, Falkovskaia, Elena, Jurica, Melissa S, Boeger, Hinrich

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Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates von Nair, Jayaprakash K, Attarwala, Husain, Sehgal, Alfica, Wang, Qianfan, Aluri, Krishna, Zhang, Xuemei, Gao, Minggeng, Liu, Ju, Indrakanti, Ramesh, Schofield, Sally, Kretschmer, Philip, Brown, Christopher R, Gupta, Swati, Willoughby, Jennifer L S, Boshar, Julie A, Jadhav, Vasant, Charisse, Klaus, Zimmermann, Tracy, Fitzgerald, Kevin, Manoharan, Muthiah, Rajeev, Kallanthottathil G, Akinc, Akin, Hutabarat, Renta, Maier, Martin A

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siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2 von Elkayam, Elad, Parmar, Rubina, Brown, Christopher R, Willoughby, Jennifer L, Theile, Christopher S, Manoharan, Muthiah, Joshua-Tor, Leemor

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Nucleosomal promoter variation generates gene expression noise von Brown, Christopher R., Boeger, Hinrich

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Single gene analysis in yeast suggests nonequilibrium regulatory dynamics for transcription von Shelansky, Robert, Abrahamsson, Sara, Brown, Christopher R., Doody, Michael, Lenstra, Tineke L., Larson, Daniel R., Boeger, Hinrich

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Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing von Jahns, Hartmut, Degaonkar, Rohan, Podbevsek, Peter, Gupta, Swati, Bisbe, Anna, Aluri, Krishna, Szeto, John, Kumar, Pawan, LeBlanc, Sarah, Racie, Tim, Brown, Christopher R, Castoreno, Adam, Guenther, Dale C, Jadhav, Vasant, Maier, Martin A, Plavec, Janez, Egli, Martin, Manoharan, Muthiah, Zlatev, Ivan

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EEG differences in children between eyes-closed and eyes-open resting conditions von Barry, Robert J, Clarke, Adam R, Johnstone, Stuart J, Brown, Christopher R

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Facile Synthesis, Geometry, and 2′-Substituent-Dependent in Vivo Activity of 5′‑(E)- and 5′‑(Z)‑Vinylphosphonate-Modified siRNA Conjugates von Parmar, Rubina Giare, Brown, Christopher R, Matsuda, Shigeo, Willoughby, Jennifer L. S, Theile, Christopher S, Charissé, Klaus, Foster, Donald J, Zlatev, Ivan, Jadhav, Vasant, Maier, Martin A, Egli, Martin, Manoharan, Muthiah, Rajeev, Kallanthottathil G

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The prenucleosome, a stable conformational isomer of the nucleosome von Fei, Jia, Torigoe, Sharon E, Brown, Christopher R, Khuong, Mai T, Kassavetis, George A, Boeger, Hinrich, Kadonaga, James T

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Genome-Wide Localization of the Nuclear Transport Machinery Couples Transcriptional Status and Nuclear Organization von Casolari, Jason M, Brown, Christopher R, Komili, Suzanne, West, Jason, Hieronymus, Haley, Silver, Pamela A

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RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes von Subramanian, Megha, McIninch, James, Zlatev, Ivan, Schlegel, Mark K., Kaittanis, Charalambos, Nguyen, Tuyen, Agarwal, Saket, Racie, Timothy, Alvarado, Martha Arbaiza, Wassarman, Kelly, Collins, Thomas S., Chickering, Tyler, Brown, Christopher R., Schmidt, Karyn, Castoreno, Adam B., Shulga-Morskaya, Svetlana, Stamenova, Elena, Buckowing, Kira, Berman, Daniel, Barry, Joseph D., Bisbe, Anna, Maier, Martin A., Fitzgerald, Kevin, Jadhav, Vasant

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Comparison of Superior-Level Facet Joint Violations During Open and Percutaneous Pedicle Screw Placement von Babu, Ranjith, Park, Jong G., Mehta, Ankit I., Shan, Tony, Grossi, Peter M., Brown, Christopher R., Richardson, William J., Isaacs, Robert E., Bagley, Carlos A., Kuchibhatla, Maragatha, Gottfried, Oren N.

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Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes von Brown, Christopher R, Kennedy, Caleb J, Delmar, Valerie A, Forbes, Douglass J, Silver, Pamela A

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Extreme lateral interbody fusion for the treatment of adult degenerative scoliosis von Caputo, Adam M, Michael, Keith W, Chapman, Todd M, Jennings, Jason M, Hubbard, Elizabeth W, Isaacs, Robert E, Brown, Christopher R

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Developmentally induced changes in transcriptional program alter spatial organization across chromosomes von Casolari, Jason M, Brown, Christopher R, Drubin, David A, Rando, Oliver J, Silver, Pamela A

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Palmitoylation regulates norepinephrine transporter uptake, surface localization, and total expression with pathogenic implications in postural orthostatic tachycardia syndrome von Brown, Christopher R, Shetty, Madhur, Foster, James D

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Occlusion of regulatory sequences by promoter nucleosomes in vivo von Mao, Changhui, Brown, Christopher R, Griesenbeck, Joachim, Boeger, Hinrich

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C5 palsy after cervical laminectomy and fusion: does width of laminectomy matter? von Klement, Mitchell R., MD, Kleeman, Lindsay T., MD, Blizzard, Daniel J., MD, MS, Gallizzi, Michael A., MD, MS, Eure, Megan, MS, Brown, Christopher R., MD

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Attenuation of Inflammatory Events in Human Intervertebral Disc Cells With a Tumor Necrosis Factor Antagonist von SINCLAIR, S. Michael, SHAMJI, Mohammed F, JUN CHEN, LIUFANG JING, RICHARDSON, William J, BROWN, Christopher R, FITCH, Robert D, SETTON, Lori A

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