PEG conjugates of potent α4 integrin inhibitors, maintaining sustained levels and bioactivity in vivo, following subcutaneous administration von Smith, Jenifer L., Rossiter, Kassandra I., Semko, Christopher M., Xu, Ying-Zi, Quincy, David A., Jagodzinski, Jacek, Dappen, Michael S., Konradi, Andrei W., Vandevert, Christopher, Garrido, Caroline, Mao, Wenxian, San Pablo, F. Bong, Wipke, Brian, Dofiles, Lilibeth, Wadsworth, Angie, Peterson, Eric, Lorenzana, Carlos, Simmonds, Stellanie, Messersmith, Elizabeth K., Bard, Frederique, Pleiss, Michael A., Yednock, Ted A.

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Arylsulfonamide pyrimidines as VLA-4 antagonists von Xu, Ying-zi, Konradi, Andrei W., Bard, Frederique, Dappen, Michael, Dofiles, Lilibeth, Dreyer, Mark, Gallager, Ian, Garrido, Caroline, Krimm, Mike, Liao, Zhenmei, Messersmith, Elizabeth, Mutter, Linda, Pleiss, Michael A., Samant, Bhushan, Semko, Christopher M., Smith, Jennifer, Stappenbeck, Frank, Stupi, Brian, Vandervert, Chris, Welch, Brent, Wipke, Brian, Yednock, Ted

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Orally available and efficacious α4β1/α4β7 integrin inhibitors von Xu, Ying-zi, Smith, Jenifer L., Semko, Christopher M., Rossiter, Kassandra I., Fukuda, Juri Y., Dappen, Michael S., Quincy, David A., Konradi, Andrei W., Mao, Wenxian, Welch, Brent, Dreyer, Mark L., Samant, Bhushan, Zhang, Hongbin, Lugar, Judevin, Liao, Zhenmei, Henschel, Carrol, Petersen, Eric, Vandevert, Christopher, Shoemaker, Mark, Wehner, Nancy, Mutter, Linda, Shopp, George, Krimm, Michael, Chen, Linda, Wipke, Brian, Dofiles, Lilibeth, Gallager, Ian, Sauer, John-Michael, Messersmith, Elizabeth K., Pleiss, Michael A., Bard, Frederique, Yednock, Ted A.

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Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease von Basi, Guriqbal S, Hemphill, Susanna, Brigham, Elizabeth F, Liao, Anna, Aubele, Danielle L, Baker, Jeanne, Barbour, Robin, Bova, Michael, Chen, Xiao-Hua, Dappen, Michael S, Eichenbaum, Tovah, Goldbach, Erich, Hawkinson, Jon, Lawler-Herbold, Rose, Hu, Kang, Hui, Terence, Jagodzinski, Jacek J, Keim, Pamela S, Kholodenko, Dora, Latimer, Lee H, Lee, Mike, Marugg, Jennifer, Mattson, Matthew N, McCauley, Scott, Miller, James L, Motter, Ruth, Mutter, Linda, Neitzel, Martin L, Ni, Huifang, Nguyen, Lan, Quinn, Kevin, Ruslim, Lany, Semko, Christopher M, Shapiro, Paul, Smith, Jenifer, Soriano, Ferdie, Szoke, Balazs, Tanaka, Kevin, Tang, Pearl, Tucker, John A, Ye, Xiacong Michael, Yu, Mei, Wu, Jing, Xu, Ying-Zi, Garofalo, Albert W, Sauer, John Michael, Konradi, Andrei W, Ness, Daniel, Shopp, George, Pleiss, Michael A, Freedman, Stephen B, Schenk, Dale

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Discovery of sulfonamide–pyrazole γ-secretase inhibitors von Mattson, Matthew N., Neitzel, Martin L., Quincy, David A., Semko, Christopher M., Garofalo, Albert W., Keim, Pamela S., Konradi, Andrei W., Pleiss, Michael A., Sham, Hing L., Brigham, Elizabeth F., Goldbach, Erich G., Zhang, Hongbin, Sauer, John-Michael, Basi, Guriqbal S.

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Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma model von Semko, Christopher M., Chen, Linda, Dressen, Darren B., Dreyer, Mark L., Dunn, Whitney, Farouz, Francine S., Freedman, Stephen B., Holsztynska, Elizabeth J., Jefferies, Michael, Konradi, Andrei W., Liao, Anna, Lugar, Judevin, Mutter, Linda, Pleiss, Michael A., Quinn, Kevin P., Thompson, Thomas, Thorsett, Eugene D., Vandevert, Christopher, Xu, Ying-Zi, Yednock, Ted A.

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Synthesis, characterization and evaluation of pro-drugs of VLA-4 antagonists von Huryn, Donna M, Ashwell, Susan, Baudy, Reinhardt, Dressen, Darren B, Gallaway, William, Grant, Francine S, Konradi, Andrei, Ley, Robert W, Petusky, Susan, Pleiss, Michael A, Sarantakis, Dimitri, Semko, Christopher M, Sherman, Mary M, Tio, Cesar, Zhang, Lu

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Carbonyl addition and alkylation reactions of isothiazolidine 1-oxide, the sulfur analog of 2-pyrrolidone von Semko, Christopher M, Casale, Kristin G, Doi, Joyce Takahashi, Musker, W. Kenneth

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Corrigendum to “Synthesis, characterization, and evaluation of pro-drugs of VLA-4 antagonists” von Huryn, D.M., Ashwell, Susan, Baudy, Reinhardt, Dressen, Darren B., Gallaway, William, Grant, Francine S., Konradi, Andrei, Ley, Robert W., Petusky, Susan, Pleiss, Michael A., Sarantakis, Dimitri, Semko, Christopher M., Sherman, Mary M., Tio, Cesar, Zhang, Lu

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COMPOSITION FOR A TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS von Yednock, Ted, Freedman, Stephen, Pleiss, Michael A, Grant, Francine S, Dressen, Daren, Semko, Christopher M, Karlik, Steve J, Konradi, Andrei W, Messersmith, Elizabeth

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FUSED, TRICYCLIC SULFONAMIDE INHIBITORS OF GAMMA SECRETASE von KONRADI, ANDREI W, GAROFALO, ALBERT W, AUBELE, DANIELLE, L, HOM, ROY, NEITZEL, MARTIN L, SEMKO, CHRISTOPHER M, TRUONG, ANH P, PROBST, GARY

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ANTAGONISTES MULTIVALENTS DE L'ANTIGENE VLA-4 COMPORTANT DES FRACTIONS POLYMERES von PLEISS, MICHAEL, A, SEMKO, CHRISTOPHER, M, KONRADI, ANDREI, W, YEDNOCK, THEODORE, SMITH, JENIFER, L

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SULFONAMIDES TRICYCLIQUES CONDENSES INHIBITEURS DE GAMMA-SECRETASE von SEMKO, CHRISTOPHER, M, KONRADI, ANDREI, W, AUBELE, DANIELLE, L, GAROFALO, ALBERT, W, HOM, ROY, NEITZEL, MARTIN, L, PROBST, GARY, TRUONG, ANH, P

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(ARYLSULFONYL)-PYRASOLOPIPERIDINES von YE, XIAOCONG, MICHAEL, SEMKO, CHRISTOPHER, M, KONRADI, ANDREI, W, GAROFALO, ALBERT, W, XU, YING-ZI, JAGODZINSKI, JACEK, J, SMITH, JENIFER, L

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Metal complexes of new chiral tridentate ligands with N, P and S donors: The crystal structure of [( S)-Ph 2POCH 2CH(NMe 2)CH 2CH 2SCH 3]W(CO) 3 von Faller, J.W., Zhang, Naijie, Chase, Kevin J., Musker, W.Kenneth, Amaro, Anthony R., Semko, Christopher M.

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Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds von KONRADI ANDREI W, DAPPEN MICHAEL S, SMITH JENIFER L, SEMKO CHRISTOPHER M

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PREPARATION OF POLYMER CONJUGATES OF THERAPEUTIC, AGRICULTURAL, AND FOOD ADDITIVE COMPOUNDS von SEMKO, CHRISTOPHER, M, KONRADI, ANDREI, W, DAPPEN, MICHAEL, S, SMITH, JENIFER, L

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Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds von KONRADI, ANDREI W, DAPPEN, MICHAEL S, SEMKO, CHRISTOPHER M, SMITH, JENIFER L

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Multimeric VLA-4 Antagonists Comprising Polymers Moieties von PLEISS MICHAEL A, YEDNOCK THEODORE, KONRADI ANDREI W, SEMKO CHRISTOPHER M, SMITH JENIFER L

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Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds von KONRADI ANDREI W, DAPPEN MICHAEL S, SMITH JENIFER L, SEMKO CHRISTOPHER M

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