A long-acting C-natriuretic peptide for achondroplasia von Schneider, Eric L, Carreras, Christopher W, Reid, Ralph, Ashley, Gary W, Santi, Daniel V

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Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice von Finn, Patricia D, Rodriguez, David, Kohler, Jill, Jiang, Zhengfeng, Wan, Sindy, Blanco, Erick, King, Andrew J, Chen, Tao, Bell, Noah, Dragoli, Dean, Jacobs, Jeffrey W, Jain, Rakesh, Leadbetter, Michael, Siegel, Matthew, Carreras, Christopher W, Koo-McCoy, Samantha, Shaw, Karen, Le, Cathy, Vanegas, Sandra, Hsu, I-Hsin, Kozuka, Kenji, Okamoto, Keiko, Caldwell, Jeremy S, Lewis, Jason G

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A platform technology for ultra-long acting intratumoral therapy von Henise, Jeff, Hangasky, John A., Charych, Deborah, Carreras, Christopher W., Ashley, Gary W., Santi, Daniel V.

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Long-Acting Poly(ADP-ribose) Polymerase Inhibitor Prodrug for Humans von Carreras, Christopher W., Fontaine, Shaun D., Reid, Ralph R., Ashley, Gary W., Santi, Daniel V.

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Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD von Labonté, Eric D, Carreras, Christopher W, Leadbetter, Michael R, Kozuka, Kenji, Kohler, Jill, Koo-McCoy, Samantha, He, Limin, Dy, Edward, Black, Deborah, Zhong, Ziyang, Langsetmo, Ingrid, Spencer, Andrew G, Bell, Noah, Deshpande, Desiree, Navre, Marc, Lewis, Jason G, Jacobs, Jeffrey W, Charmot, Dominique

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Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5) von Chen, Tao, Reich, Nicholas William, Bell, Noah, Finn, Patricia D, Rodriguez, David, Kohler, Jill, Kozuka, Kenji, He, Limin, Spencer, Andrew G, Charmot, Dominique, Navre, Marc, Carreras, Christopher W, Koo-McCoy, Samantha, Tabora, Jocelyn, Caldwell, Jeremy S, Jacobs, Jeffrey W, Lewis, Jason Gustaf

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Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na+/H+ Exchanger Isoform 3 von Jacobs, Jeffrey W., Leadbetter, Michael R., Bell, Noah, Koo-McCoy, Samantha, Carreras, Christopher W., He, Limin, Kohler, Jill, Kozuka, Kenji, Labonté, Eric D., Navre, Marc, Spencer, Andrew G., Charmot, Dominique

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A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors von Fontaine, Shaun D, Carreras, Christopher W, Reid, Ralph R, Ashley, Gary W, Santi, Daniel V

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Synthesis and biological activities of novel 17-aminogeldanamycin derivatives von Tian, Zong-Qiang, Liu, Yaoquan, Zhang, Dan, Wang, Zhan, Dong, Steven D., Carreras, Christopher W., Zhou, Yiqing, Rastelli, Giulio, Santi, Daniel V., Myles, David C.

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Potent Cytotoxic C-11 Modified Geldanamycin Analogues von Tian, Zong-Qiang, Wang, Zhan, MacMillan, Karen S, Zhou, Yiqing, Carreras, Christopher W, Mueller, Thomas, Myles, David C, Liu, Yaoquan

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The Catalytic Mechanism and Structure of Thymidylate Synthase von Carreras, C W, Santi, D V

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The role of the 4′′-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series von Liu, Yaoquan, Carreras, Christopher W., Claypool, Mark, Myles, David C., Shaw, Simon J.

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Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD von Labonté, Eric D., Carreras, Christopher W., Leadbetter, Michael R., Kozuka, Kenji, Kohler, Jill, Koo-McCoy, Samantha, He, Limin, Dy, Edward, Black, Deborah, Zhong, Ziyang, Langsetmo, Ingrid, Spencer, Andrew G., Bell, Noah, Deshpande, Desiree, Navre, Marc, Lewis, Jason G., Jacobs, Jeffrey W., Charmot, Dominique

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9-Dihydroerythromycin ethers as motilin agonists—Developing structure–activity relationships for potency and safety von Liu, Yaoquan, Li, Yong, Myles, David C., Claypool, Mark, Carreras, Christopher W., Shaw, Simon J.

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9-Dihydroerythromycins as non-antibiotic motilin receptor agonists von Liu, Yaoquan, Li, Yong, Chen, Yue, Zheng, Hao, Claypool, Mark, Myles, David C., Carreras, Christopher W.

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Structure−Activity Relationships of 9-Substituted-9-Dihydroerythromycin-Based Motilin Agonists: Optimizing for Potency and Safety von Shaw, Simon J, Chen, Yue, Zheng, Hao, Fu, Hong, Burlingame, Mark A, Marquez, Saul, Li, Yong, Claypool, Mark, Carreras, Christopher W, Crumb, William, Hardy, Dwight J, Myles, David C, Liu, Yaoquan

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Purification and in Vitro Reconstitution of the Essential Protein Components of an Aromatic Polyketide Synthase von Carreras, Christopher W, Khosla, Chaitan

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RDX5791, a First-in-Class Minimally Systemic NHE3 Inhibitor in Clinical Development for CIC and IBS-C, Increases Intestinal Sodium Leading to Enhanced Intestinal Fluid Volume and T... von Spencer, Andrew G, Jacobs, Jeffrey W, Leadbetter, Michael R, Carreras, Christopher W, Du, Xunxiang, Bell, Noah, Koo-McCoy, Samantha, Kohler, Jill N, Labonté, Eric, Rosenbaum, David P, Navre, Marc, Charmot, Dominique

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Filter binding assay for the geldanamycin–heat shock protein 90 interaction von Carreras, Christopher W., Schirmer, Andreas, Zhong, Ziyang, Santi, Daniel V.

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Utilization of Enzymatically Phosphopantetheinylated Acyl Carrier Proteins and Acetyl−Acyl Carrier Proteins by the Actinorhodin Polyketide Synthase von Carreras, Christopher W, Gehring, Amy M, Walsh, Christopher T, Khosla, Chaitan

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