A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells von Michalon, Aubin, Hagenbuch, Andreas, Huy, Christian, Varela, Evita, Combaluzier, Benoit, Damy, Thibaud, Suhr, Ole B., Saraiva, Maria J., Hock, Christoph, Nitsch, Roger M., Jan Grimm

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Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid von Garcia-Pavia, Pablo, aus dem Siepen, Fabian, Donal, Erwan, Lairez, Olivier, van der Meer, Peter, Kristen, Arnt V., Mercuri, Michele F., Michalon, Aubin, Frost, Robert J.A., Grimm, Jan, Nitsch, Roger M., Hock, Christoph, Kahr, Peter C., Damy, Thibaud

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Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression von Liebsch, Filip, Kulic, Luka, Teunissen, Charlotte, Shobo, Adeola, Ulku, Irem, Engelschalt, Vivienne, Hancock, Mark A., van der Flier, Wiesje M., Kunach, Peter, Rosa-Neto, Pedro, Scheltens, Philip, Poirier, Judes, Saftig, Paul, Bateman, Randall J., Breitner, John, Hock, Christoph, Multhaup, Gerhard

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Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients von Birnbaum, Julian H., Wanner, Debora, Gietl, Anton F., Saake, Antje, Kündig, Thomas M., Hock, Christoph, Nitsch, Roger M., Tackenberg, Christian

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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro von Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hock, Christoph, Nitsch, Roger M., Montrasio, Fabio, Grimm, Jan, Cheung, Anne E., Dunah, Anthone W., Wittmann, Marion, Bussiere, Thierry, Weinreb, Paul H., Hyman, Bradley T., Takeda, Shuko

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Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis von Ulku, Irem, Liebsch, Filip, Akerman, S. Can, Schulz, Jana F., Kulic, Luka, Hock, Christoph, Pietrzik, Claus, Di Spiezio, Alessandro, Thinakaran, Gopal, Saftig, Paul, Multhaup, Gerhard

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A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models von Wirth, Fabian, Heitz, Fabrice D., Seeger, Christine, Combaluzier, Ioana, Breu, Karin, Denroche, Heather C., Thevenet, Julien, Osto, Melania, Arosio, Paolo, Kerr-Conte, Julie, Verchere, C. Bruce, Pattou, François, Lutz, Thomas A., Donath, Marc Y., Hock, Christoph, Nitsch, Roger M., Grimm, Jan

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Age-, sex-, and pathology-related variability in brain structure and cognition von Bachmann, Dario, Buchmann, Andreas, Studer, Sandro, Saake, Antje, Rauen, Katrin, Zuber, Isabelle, Gruber, Esmeralda, Nitsch, Roger M., Hock, Christoph, Gietl, Anton, Treyer, Valerie

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Automatic analysis of skull thickness, scalp-to-cortex distance and association with age and sex in cognitively normal elderly von Zhang, Junhao, Treyer, Valerie, Sun, Junfeng, Zhang, Chencheng, Gietl, Anton, Hock, Christoph, Razansky, Daniel, Nitsch, Roger M., Ni, Ruiqing

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Physical activity is associated with lower cerebral beta-amyloid and cognitive function benefits from lifetime experience-a study in exceptional aging von Treyer, Valerie, Meyer, Rafael S, Buchmann, Andreas, Crameri, Giovanni A G, Studer, Sandro, Saake, Antje, Gruber, Esmeralda, Unschuld, Paul G, Nitsch, Roger M, Hock, Christoph, Gietl, Anton F

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White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition von Bachmann, Dario, von Rickenbach, Bettina, Buchmann, Andreas, Hüllner, Martin, Zuber, Isabelle, Studer, Sandro, Saake, Antje, Rauen, Katrin, Gruber, Esmeralda, Nitsch, Roger M, Hock, Christoph, Treyer, Valerie, Gietl, Anton

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The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease von Kirabali, Tunahan, Rigotti, Serena, Siccoli, Alessandro, Liebsch, Filip, Shobo, Adeola, Hock, Christoph, Nitsch, Roger M, Multhaup, Gerhard, Kulic, Luka

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Low-Dose Cortisol for Symptoms of Posttraumatic Stress Disorder von Aerni, Amanda, Traber, Rafael, Hock, Christoph, Roozendaal, Benno, Schelling, Gustav, Papassotiropoulos, Andreas, Nitsch, Roger M., Schnyder, Ulrich, de Quervain, Dominique J.-F.

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Common Genetic Variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and Late-Onset Alzheimer's Disease von De Ferrari, Giancarlo V., Papassotiropoulos, Andreas, Biechele, Travis, De-Vrieze, Fabienne Wavrant, Avila, Miguel E., Major, Michael B., Myers, Amanda, Sáez, Katia, Henríquez, Juan P., Zhao, Alice, Wollmer, M. Axel, Nitsch, Roger M., Hock, Christoph, Morris, Chris M., Hardy, John, Moon, Randall T.

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Changes of Functional and Directed Resting-State Connectivity Are Associated with Neuronal Oscillations, ApoE Genotype and Amyloid Deposition in Mild Cognitive Impairment von Michels, Lars, Muthuraman, Muthuraman, Anwar, Abdul R, Kollias, Spyros, Leh, Sandra E, Riese, Florian, Unschuld, Paul G, Siniatchkin, Michael, Gietl, Anton F, Hock, Christoph

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Low Subicular Volume as an Indicator of Dementia-Risk Susceptibility in Old Age von Kagerer, Sonja M, Schroeder, Clemens, van Bergen, Jiri M G, Schreiner, Simon J, Meyer, Rafael, Steininger, Stefanie C, Vionnet, Laetitia, Gietl, Anton F, Treyer, Valerie, Buck, Alfred, Pruessmann, Klaas P, Hock, Christoph, Unschuld, Paul G

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EEG-fMRI Signal Coupling Is Modulated in Subjects With Mild Cognitive Impairment and Amyloid Deposition von Michels, Lars, Riese, Florian, Meyer, Rafael, Kälin, Andrea M, Leh, Sandra E, Unschuld, Paul G, Luechinger, Roger, Hock, Christoph, O'Gorman, Ruth, Kollias, Spyros, Gietl, Anton

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Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4 von Quevenco, Frances C, van Bergen, Jiri M, Treyer, Valerie, Studer, Sandro T, Kagerer, Sonja M, Meyer, Rafael, Gietl, Anton F, Kaufmann, Philipp A, Nitsch, Roger M, Hock, Christoph, Unschuld, Paul G

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Explaining variability in early stages of [18F]‐flortaucipir tau‐PET binding: Focus on sex differences von Bachmann, Dario, Buchmann, Andreas, Studer, Sandro, Saake, Antje, Rauen, Katrin, Gruber, Esmeralda, Nitsch, Roger M., Hock, Christoph, Gietl, Anton, Treyer, Valerie

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Gray matter gamma‐hydroxy‐butyric acid and glutamate reflect beta‐amyloid burden at old age von Schreiner, Simon J., Van Bergen, Jiri M. G., Gietl, Anton F., Buck, Alfred, Hock, Christoph, Pruessmann, Klaas P., Henning, Anke, Unschuld, Paul G.

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