Novel Aza-analogous Ergoline Derived Scaffolds as Potent Serotonin 5‑HT6 and Dopamine D2 Receptor Ligands von Krogsgaard-Larsen, Niels, Jensen, Anders A, Schrøder, Tenna J, Christoffersen, Claus. T, Kehler, Jan

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A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission von Nielsen, Jacob, Fejgin, Kim, Sotty, Florence, Nielsen, Vibeke, Mørk, Arne, Christoffersen, Claus T., Yavich, Leonid, Lauridsen, Jes B., Clausen, Dorte, Larsen, Peter H., Egebjerg, Jan, Werge, Thomas M., Kallunki, Pekka, Christensen, Kenneth V., Didriksen, Michael

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Phosphodiesterase 1 Bridges Glutamate Inputs with NO- and Dopamine-Induced Cyclic Nucleotide Signals in the Striatum von Betolngar, Dahdjim B, Mota, Élia, Fabritius, Arne, Nielsen, Jacob, Hougaard, Charlotte, Christoffersen, Claus T, Yang, Jun, Kehler, Jan, Griesbeck, Oliver, Castro, Liliana R V, Vincent, Pierre

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Debenzylative Cycloetherification as a Synthetic Tool in the Diastereoselective Synthesis of 3,6-Disubstituted Hexahydro-2 H -furo[3,2- b ]pyrroles, PDE1 Enzyme Inhibitors with an... von Castán, Alejandro, Badorrey, Ramón, Díez, José A, Christoffersen, Claus T, Rasmussen, Lars K, Kehler, Jan, Köhler, Ralf, Gálvez, José A, Díaz-de-Villegas, María D

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Debenzylative Cycloetherification as a Synthetic Tool in the Diastereoselective Synthesis of 3,6-Disubstituted Hexahydro‑2H‑furo[3,2‑b]pyrroles, PDE1 Enzyme Inhibitors with an Anti... von Castán, Alejandro, Badorrey, Ramón, Díez, José A, Christoffersen, Claus T, Rasmussen, Lars K, Kehler, Jan, Köhler, Ralf, Gálvez, José A, Díaz-de-Villegas, María D

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In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia von Redrobe, John P., Jørgensen, Morten, Christoffersen, Claus T., Montezinho, Liliana P., Bastlund, Jesper F., Carnerup, Martin, Bundgaard, Christoffer, Lerdrup, Linda, Plath, Niels

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Characterisation of Lu AF33241: A novel, brain-penetrant, dual inhibitor of phosphodiesterase (PDE) 2A and PDE10A von Redrobe, John P., Rasmussen, Lars K., Christoffersen, Claus T., Bundgaard, Christoffer, Jørgensen, Morten

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Elucidation of fluorine's impact on pKa and in vitro Pgp-mediated efflux for a series of PDE9 inhibitors von Kasper Fjelbye, Marigo, Mauro, Clausen, Rasmus P, Jørgensen, Erling B, Christoffersen, Claus T, Juhl, Karsten

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Elucidation of fluorine's impact on p K a and in vitro Pgp-mediated efflux for a series of PDE9 inhibitors von Fjelbye, Kasper, Marigo, Mauro, Clausen, Rasmus P, Jørgensen, Erling B, Christoffersen, Claus T, Juhl, Karsten

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Poster #S202 CHARACTERIZATION OF A NUMBER OF ATYPICAL ANTIPSYCHOTICS IN VITRO von Christoffersen, Claus T, Holm, K, Ruskov-Nielsen, A, Nielsen, J

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Synthesis and SAR study of a novel series of dopamine receptor agonists von Risgaard, Rune, Jensen, Martin, Jørgensen, Morten, Bang-Andersen, Benny, Christoffersen, Claus T., Jensen, Klaus G., Kristensen, Jesper L., Püschl, Ask

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Discovery of novel α1-adrenoceptor ligands based on the antipsychotic sertindole suitable for labeling as PET ligands von Jørgensen, Morten, Jørgensen, Pernille N., Christoffersen, Claus T., Jensen, Klaus G., Balle, Thomas, Bang-Andersen, Benny

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Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity for α(1)-adrenoceptors von Kristensen, Jesper L, Püschl, Ask, Jensen, Martin, Risgaard, Rune, Christoffersen, Claus T, Bang-Andersen, Benny, Balle, Thomas

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Exploring the Neuroleptic Substituent in Octoclothepin: Potential Ligands for Positron Emission Tomography with Subnanomolar Affinity for α1-Adrenoceptors von Kristensen, Jesper L, Püschl, Ask, Jensen, Martin, Risgaard, Rune, Christoffersen, Claus T, Bang-Andersen, Benny, Balle, Thomas

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Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based ω-acidic amino acids as glutamate receptors ligands von Filosa, Rosanna, Carmela Fulco, M., Marinozzi, Maura, Giacchè, Nicola, Macchiarulo, Antonio, Peduto, Antonella, Massa, Antonio, de Caprariis, Paolo, Thomsen, Christian, Christoffersen, Claus T., Pellicciari, Roberto

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Lu 35-138 ( (+ ) -(S ) -3-{1 -[2 -(1 -acetyl -2,3 -dihydro -1H -indol -3 -yl )ethyl] -3, 6 -dihydro -2H -pyridin -4 -yl} -6 -chloro -1H -indole ), a dopamine D4 receptor antagonist... von HERTEL, Peter, DIDRIKSEN, Michael, DI MAFLEO, Vincenzo, ESPOSITO, Ennio, BANG-ANDERSEN, Benny, ARMT, Jøm, POUZET, Bruno, BRENNUM, Lise T, SØBY, Karina K, LARSEN, Anna Kirstine, CHRISTOFFERSEN, Claus T, RAMIREZ, Teresa, MARCUS, Monica M, SVENSSON, Torgny H

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Development of an aequorin luminescence calcium assay for high-throughput screening using a plate reader, the LumiLux von Menon, Veena, Ranganathn, Arun, Jorgensen, Vincent H, Sabio, Michael, Christoffersen, Claus T, Uberti, Michelle A, Jones, Kenneth A, Babu, Poda Suresh

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Development of an Aequorin Luminescence Calcium Assay for High-Throughput Screening Using a Plate Reader, the LumiLux von Menon, Veena, Ranganathn, Arun, Jorgensen, Vincent H., Sabio, Michael, Christoffersen, Claus T., Uberti, Michelle A., Jones, Kenneth A., Babu, Poda Suresh

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PROGRESS TOWARDS AN A‐SYNUCLEIN PET TRACER von Tempest, Paul, Tai, Chin‐Yin, Ono, Maiko, Skaddan, Marc B, Wilcox, Kyle C, Reed, Aimee, Vaidyanathan, Srirajan, Christoffersen, Claus T, Kallunki, Pekka, Bang‐Andersen, Benny, Margolin, Richard A, Kao, Tzu‐Huei, Higuchi, Makoto, Jang, Ming‐Kuei

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IRS-4 mediated mitogenic signalling by insulin and growth hormone in LB cells, a murine T-cell lymphoma devoid of IGF-I receptors von Ursø, Birgitte, Ilondo, M.Mapoko, Holst, Patricia A, Christoffersen, Claus T, Ouwens, Margriet, Giorgetti, Sophie, Van Obberghen, E, Naor, David, Tornqvist, Hans, De Meyts, Pierre

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