Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation von Jänne, Pasi A., Riely, Gregory J., Gadgeel, Shirish M., Heist, Rebecca S., Ou, Sai-Hong I., Pacheco, Jose M., Johnson, Melissa L., Sabari, Joshua K., Leventakos, Konstantinos, Yau, Edwin, Bazhenova, Lyudmila, Negrao, Marcelo V., Pennell, Nathan A., Zhang, Jun, Anderes, Kenna, Der-Torossian, Hirak, Kheoh, Thian, Velastegui, Karen, Yan, Xiaohong, Christensen, James G., Chao, Richard C., Spira, Alexander I.

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Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer von Kemp, Samantha B, Cheng, Noah, Markosyan, Nune, Sor, Rina, Kim, Il-Kyu, Hallin, Jill, Shoush, Jason, Quinones, Liz, Brown, Natalie V, Bassett, Jared B, Joshi, Nikhil, Yuan, Salina, Smith, Molly, Vostrejs, William P, Perez-Vale, Kia Z, Kahn, Benjamin, Mo, Feiyan, Donahue, Timothy R, Radu, Caius G, Clendenin, Cynthia, Christensen, James G, Vonderheide, Robert H, Stanger, Ben Z

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Lack of association between human plasma oxytocin and interpersonal trust in a Prisoner's Dilemma paradigm von Christensen, James C, Shiyanov, Pavel A, Estepp, Justin R, Schlager, John J

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First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRASG12C Solid Tumors (KRYSTAL-1) von Ou, Sai-Hong Ignatius, Jänne, Pasi A., Leal, Ticiana A., Rybkin, Igor I., Sabari, Joshua K., Barve, Minal A., Bazhenova, Lyudmila, Johnson, Melissa L., Velastegui, Karen L., Cilliers, Cornelius, Christensen, James G., Yan, Xiaohong, Chao, Richard C., Papadopoulos, Kyriakos P.

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Bullying Victimization and Youth's Likelihood of Carrying a Handgun von Christensen, James B, Jones, Melissa S, Hoffmann, John P

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Enhanced efficacy of sitravatinib in metastatic models of antiangiogenic therapy resistance von Dolan, Melissa, Mastri, Michalis, Tracz, Amanda, Christensen, James G, Chatta, Gurkamal, Ebos, John M L

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c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention von Christensen, James G., Burrows, Jon, Salgia, Ravi

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The MET Receptor Tyrosine Kinase Is a Potential Novel Therapeutic Target for Head and Neck Squamous Cell Carcinoma von SEIWERT, Tanguy Y, JAGADEESWARAN, Ramasamy, MARTIN, Leslie, KRISHNASWAMY, Soundararajan, KLEIN-SZANTO, Andres, CHRISTENSEN, James G, VOKES, Everett E, SALGIA, Ravi, FAORO, Leonardo, JANAMANCHI, Varalakshmi, NALLASURA, Vidya, MOHAMED EL DINALI, YALA, Soheil, KANTETI, Rajani, COHEN, Ezra E. W, LINGEN, Mark W

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Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC von Turke, Alexa B., Zejnullahu, Kreshnik, Wu, Yi-Long, Song, Youngchul, Dias-Santagata, Dora, Lifshits, Eugene, Toschi, Luca, Rogers, Andrew, Mok, Tony, Sequist, Lecia, Lindeman, Neal I., Murphy, Carly, Akhavanfard, Sara, Yeap, Beow Y., Xiao, Yun, Capelletti, Marzia, Iafrate, A. John, Lee, Charles, Christensen, James G., Engelman, Jeffrey A., Jänne, Pasi A.

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Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer von Sabari, Joshua K, Velcheti, Vamsidhar, Shimizu, Kazuhide, Strickland, Matthew R, Heist, Rebecca S, Singh, Mohini, Nayyar, Naema, Giobbie-Hurder, Anita, Digumarthy, Subba R, Gainor, Justin F, Rajan, Anant P, Nieblas-Bedolla, Edwin, Burns, Aaron C, Hallin, Jill, Olson, Peter, Christensen, James G, Kurz, Sylvia C, Brastianos, Priscilla K, Wakimoto, Hiroaki

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HGF/c-Met acts as an alternative angiogenic pathway in sunitinib-resistant tumors von Shojaei, Farbod, Lee, Joseph H, Simmons, Brett H, Wong, Anthony, Esparza, Carlos O, Plumlee, Pamela A, Feng, Junli, Stewart, Albert E, Hu-Lowe, Dana D, Christensen, James G

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HGF Rescues Colorectal Cancer Cells from EGFR Inhibition via MET Activation von LISKA, David, CHEN, Chin-Tung, BACHLEITNER-HOFMANN, Thomas, CHRISTENSEN, James G, WEISER, Martin R

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Acquired Resistance to Crizotinib from a Mutation in CD74–ROS1 von Awad, Mark M, Katayama, Ryohei, McTigue, Michele, Liu, Wei, Deng, Ya-Li, Brooun, Alexei, Friboulet, Luc, Huang, Donghui, Falk, Matthew D, Timofeevski, Sergei, Wilner, Keith D, Lockerman, Elizabeth L, Khan, Tahsin M, Mahmood, Sidra, Gainor, Justin F, Digumarthy, Subba R, Stone, James R, Mino-Kenudson, Mari, Christensen, James G, Iafrate, A. John, Engelman, Jeffrey A, Shaw, Alice T

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Multiple Mutations and Bypass Mechanisms Can Contribute to Development of Acquired Resistance to MET Inhibitors von JIE QI, MCTIGUE, Michele A, ROGERS, Andrew, LIFSHITS, Eugene, CHRISTENSEN, James G, JÄNNE, Pasi A, ENGELMAN, Jeffrey A

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Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers von Smith, Christopher R, Aranda, Ruth, Bobinski, Thomas P, Briere, David M, Burns, Aaron C, Christensen, James G, Clarine, Jeffery, Engstrom, Lars D, Gunn, Robin J, Ivetac, Anthony, Jean-Baptiste, Ronald, Ketcham, John M, Kobayashi, Masakazu, Kuehler, Jon, Kulyk, Svitlana, Lawson, J. David, Moya, Krystal, Olson, Peter, Rahbaek, Lisa, Thomas, Nicole C, Wang, Xiaolun, Waters, Laura M, Marx, Matthew A

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Bridging Service-Oriented Architecture and IEC 61499 for Flexibility and Interoperability von Wenbin Dai, Vyatkin, Valeriy, Christensen, James H., Dubinin, Victor N.

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Intracranial Efficacy of Adagrasib in Patients From the KRYSTAL-1 Trial With KRASG12C-Mutated Non-Small-Cell Lung Cancer Who Have Untreated CNS Metastases von Negrao, Marcelo V, Spira, Alexander I, Heist, Rebecca S, Jänne, Pasi A, Pacheco, Jose M, Weiss, Jared, Gadgeel, Shirish M, Velastegui, Karen, Yang, Wenjing, Der-Torossian, Hirak, Christensen, James G, Sabari, Joshua K

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Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma von Christensen, James G, Zou, Helen Y, Arango, Maria E, Li, Qiuhua, Lee, Joseph H, McDonnell, Scott R, Yamazaki, Shinji, Alton, Gordon R, Mroczkowski, Barbara, Los, Gerrit

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Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC von Tang, Kwan Ho, Li, Shuai, Khodadadi-Jamayran, Alireza, Jen, Jayu, Han, Han, Guidry, Kayla, Chen, Ting, Hao, Yuan, Fedele, Carmine, Zebala, John A, Maeda, Dean Y, Christensen, James G, Olson, Peter, Athanas, Argus, Loomis, Cynthia A, Tsirigos, Aristotelis, Wong, Kwok-Kin, Neel, Benjamin G

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Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy von Ebos, John M.L, Lee, Christina R, Christensen, James G, Mutsaers, Anthony J, Kerbel, Robert S

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