Hydrophobic Vancomycin Derivatives with Improved ADME Properties: Discovery of Telavancin (TD-6424) von LEADBETTER, MICHAEL R., ADAMS, STACY M., BAZZINI, BETTINA, FATHEREE, PAUL R., KARR, DANE E., KRAUSE, KEVIN M., LAM, BERNICE M. T., LINSELL, MARTIN S., NODWELL, MATTHEW B., PACE, JOHN L., QUAST, KELLY, SHAW, JENG-PYNG, SORIANO, ELIZABETH, TRAPP, SEAN G., VILLENA, JENNY D., WU, TERRY X., CHRISTENSEN, BURTON G., JUDICE, J. KEVIN

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A Multivalent Approach to Drug Discovery for Novel Antibiotics von Long, Daniel D, Aggen, James B, Christensen, Burton G, Judice, J Kevin, Hegde, Sharath S, Kaniga, Koné, Krause, Kevin M, Linsell, Martin S, Moran, Edmund J, Pace, John L

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Exploring the Positional Attachment of Glycopeptide/β-lactam Heterodimers von Long, Daniel D, Aggen, James B, Chinn, Jason, Choi, Seok-Ki, Christensen, Burton G, Fatheree, Paul R, Green, David, Hegde, Sharath S, Judice, J Kevin, Kaniga, Koné, Krause, Kevin M, Leadbetter, Michael, Linsell, Martin S, Marquess, Daniel G, Moran, Edmund J, Nodwell, Matthew B, Pace, John L, Trapp, Sean G, Turne, S Derek

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Multivalent Drug Design. Synthesis and In Vitro Analysis of an Array of Vancomycin Dimers von Griffin, John H, Linsell, Martin S, Nodwell, Matthew B, Chen, QiQi, Pace, John L, Quast, Kelly L, Krause, Kevin M, Farrington, Lesley, Wu, Terry X, Higgins, Deborah L, Jenkins, Thomas E, Christensen, Burton G, Judice, J. Kevin

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Synthesis and Structure-Activity Relationships of Peptidyl .alpha.-Keto Heterocycles as Novel Inhibitors of Prolyl Endopeptidase von Tsutsumi, Seiji, Okonogi, Tsuneo, Shibahara, Seiji, Ohuchi, Shokichi, Hatsushiba, Emiko, Patchett, Arthur A, Christensen, Burton G

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Discovery of MC-02, 331, a New Cephalosporin Exhibiting Potent Activity Against Methicillin-resistant Staphylococcus aureus von HECKER, SCOTT J., CHO, IN-SEOP, GLINKA, TOMASZ W., ZHANG, ZHIJIA J., PRICE, MARY E., LEE, VING J., CHRISTENSEN, BURTON G., BOGGS, AMY, CHAMBERLAND, SUZANNE, MALOUIN, FRANÇOIS, PARR, THOMAS R., ANNAMALAI, THAMIL, BLAIS, JOHANNE, BOND, EMMETT L., CASE, LAURA, CHAN, CHRISTINE, CRASE, JAC, FRITH, RIA, GRIFFITH, DAVID, HARFORD, LAURIE, LIU, NANCY, LUDWIKOW, MARIA, MATHIAS, KRISTINA, REA, DAVID, WILLIAMS, ROBERT

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Synthetic carbapenem antibiotics III. 1-Methyl thienamycin von Shih, David H., Cama, Lovji, Christensen, Burton G.

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Thienamycin total synthesis. 1. Synthesis of azetidinone precursors of (.+-.)-thienamycin and its stereoisomers von Bouffard, F. Aileen, Johnston, David B. R, Christensen, Burton G

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Exploring the Positional Attachment of Glycopeptide/[beta]-lactam Heterodimers von Long, Daniel D, Aggen, James B, Chinn, Jason, Choi, Seok-ki, Christensen, Burton G, Fatheree, Paul R, Green, David, Hegde, Sharath S, Judice, J Kevin, Kaniga, Koné, Krause, Kevin M, Leadbetter, Michael, Linsell, Martin S, Marquess, Daniel G, Moran, Edmund J, Nodwell, Matthew B, Pace, John L, Trapp, Sean G, Turne, S Derek

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SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NOVEL 2-METHYL-1-OXACEPHALOSPORINS von OKONOGI, TSUNEO, SHIBAHARA, SEIJI, MURAI, YASUSHI, YOSHIDA, TAKASHI, INOUYE, SHIGEHARU, KONDO, SHINICHI, CHRISTENSEN, BURTON G.

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Total synthesis of 3-(5-tetrazolyl)carbapenems von Andrus, Alex, Heck, James V, Christensen, Burton G, Partridge, Beverly

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The synthesis of 2-(functionalized methyl)-1.BETA.-methylcarbapenems von SCHMITT, SUSAN M., SALZMANN, THOMAS N., SHIH, DAVID H., CHRISTENSEN, BURTON G.

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Synthesis of a novel 2.BETA.-methyl-1-oxacephalosporin, OCP-9-176 von SHIBAHARA, SEIJI, OKONOGI, TSUNEO, MURAI, YASUSHI, KUDO, TOSHIAKI, YOSHIDA, TAKASHI, KONDO, SHINICHI, CHRISTENSEN, BURTON G.

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COMBINATORIAL SYNTHESIS OF MULTIBINDING LIBRARIES von JOHN H. GRIFFIN, THOMAS E. JENKINS, CHRISTENSEN BURTON G, BURTON G. CHRISTENSEN, J. KEVIN JUDICE, GRIFFIN JOHN H, JUDICE J. KEVIN, JENKINS THOMAS E

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α-Ketothiazole inhibitors of prolyl endopeptidase von Tsutsumi, Seiji, Okonogi, Tsuneo, Shibahara, Seiji, Patchett, Arthur A., Christensen, Burton G.

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6α-Deuteriopenicillin. Steric control of fast reversible protonation von Firestone, Raymond A., Christensen, Burton G.

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Structure and absolute configuration of thienamycin von Albers-Schoenberg, Georg, Arison, Byron H, Hensens, Otto D, Hirshfield, Jordan, Hoogsteen, Karst, Kaczka, Edward A, Rhodes, Robert E, Kahan, Jean S, Kahan, Frederick M

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SYNTHESIS OF A NOVEL 2β-METHYL-1-OXACEPHALOSPORIN, OCP-9-176 von SHIBAHARA, SEIJI, OKONOGI, TSUNEO, MURAI, YASUSHI, KUDO, TOSHIAKI, YOSHIDA, TAKASHI, KONDO, SHINICHI, CHRISTENSEN, BURTON G.

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6- and 4-substituted-1-azabicyclo(3.2.0)heptan-3, 7-dione-2-carboxylates von CHRISTENSEN, BURTON G

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THE SYNTHESIS OF 2-(FUNCTIONALIZED METHYL)-1β-METHYLCARBAPENEMS von SCHMITT, SUSAN M., SALZMANN, THOMAS N., SHIH, DAVID H., CHRISTENSEN, BURTON G.

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