A Dual Inhibition, a Better Solution: Development of a JAK1/TYK2 inhibitor von Menet, Christel J

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Development of Generic G Protein Peptidomimetics Able to Stabilize Active State Gs Protein‐Coupled Receptors for Application in Drug Discovery von Mannes, Morgane, Martin, Charlotte, Triest, Sarah, Pia Dimmito, Marilisa, Mollica, Adriano, Laeremans, Toon, Menet, Christel J., Ballet, Steven

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Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases von Van Rompaey, Luc, Galien, René, van der Aar, Ellen M, Clement-Lacroix, Philippe, Nelles, Luc, Smets, Bart, Lepescheux, Liên, Christophe, Thierry, Conrath, Katja, Vandeghinste, Nick, Vayssiere, Béatrice, De Vos, Steve, Fletcher, Stephen, Brys, Reginald, van 't Klooster, Gerben, Feyen, Jean H M, Menet, Christel

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Development of Generic G Protein Peptidomimetics Able to Stabilize Active State G s Protein-Coupled Receptors for Application in Drug Discovery von Mannes, Morgane, Martin, Charlotte, Triest, Sarah, Pia Dimmito, Marilisa, Mollica, Adriano, Laeremans, Toon, Menet, Christel J, Ballet, Steven

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Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634 von Menet, Christel J, Fletcher, Stephen R, Van Lommen, Guy, Geney, Raphael, Blanc, Javier, Smits, Koen, Jouannigot, Nolwenn, Deprez, Pierre, van der Aar, Ellen M, Clement-Lacroix, Philippe, Lepescheux, Liên, Galien, René, Vayssiere, Béatrice, Nelles, Luc, Christophe, Thierry, Brys, Reginald, Uhring, Muriel, Ciesielski, Fabrice, Van Rompaey, Luc

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Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist von Fontaine, Thomas, Busch, Andreas, Laeremans, Toon, De Cesco, Stéphane, Liang, Yi-Lynn, Jaakola, Veli-Pekka, Sands, Zara, Triest, Sarah, Masiulis, Simonas, Dekeyzer, Lies, Samyn, Noor, Loeys, Nicolas, Perneel, Lisa, Debaere, Melanie, Martini, Murielle, Vantieghem, Charlotte, Virmani, Richa, Skieterska, Kamila, Staelens, Stephanie, Barroco, Rosa, Van Roy, Maarten, Menet, Christel

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Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs von Laeremans, Toon, Sands, Zara A, Claes, Pieter, De Blieck, Ann, De Cesco, Stephane, Triest, Sarah, Busch, Andreas, Felix, David, Kumar, Abhinav, Jaakola, Veli-Pekka, Menet, Christel

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Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor von Pardon, Marie, Claes, Pieter, Druwé, Sarah, Martini, Murielle, Siekierska, Aleksandra, Menet, Christel, de Witte, Peter A. M., Copmans, Daniëlle

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Progress toward JAK1-selective inhibitors von Menet, Christel J, Mammoliti, Oscar, López-Ramos, Miriam

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Development of Generic G Protein Peptidomimetics Able to Stabilize Active State Gs Protein‐Coupled Receptors for Application in Drug Discovery von Mannes, Morgane, Martin, Charlotte, Triest, Sarah, Pia Dimmito, Marilisa, Mollica, Adriano, Laeremans, Toon, Menet, Christel J., Ballet, Steven

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Synthesis of (−)-kainic acid using chiral lithium amides in an asymmetric dearomatizing cyclization von Clayden, Jonathan, Menet, Christel J, Tchabanenko, Kirill

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Wandering beyond small molecules: peptides as allosteric protein modulators von Mannes, Morgane, Martin, Charlotte, Menet, Christel, Ballet, Steven

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Asymmetric deprotonation and dearomatising cyclisation of N-benzyl benzamides using chiral lithium amides: formal synthesis of (-)-kainic acid von Clayden, Jonathan, Menet, Christel J, Mansfield, Darren J

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Stereospecific Photochemical Ring Expansion of Lithiated Benzamides von Clayden, Jonathan, Knowles, Faye E, Menet, Christel J

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2,3-Dihydroisoindolones by cyclisation and rearomatisation of lithiated benzamides von Clayden, Jonathan, Menet, Christel J.

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Synthesis of α-methyl kainic acid by stereospecific lithiation–dearomatizing cyclization of a chiral benzamide von Clayden, Jonathan, Knowles, Faye E, Menet, Christel J

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Design of a potent and selective dual JAK1/TYK2 inhibitor von Mammoliti, Oscar, Menet, Christel, Cottereaux, Céline, Blanc, Javier, De Blieck, Ann, Coti, Ghjuvanni, Geney, Raphaël, Oste, Line, Ostyn, Koen, Palisse, Adeline, Quinton, Evelyne, Schmitt, Benoit, Borgonovi, Monica, Parent, Isabelle, Jagerschmidt, Catherine, De Vos, Steve, Vayssiere, Béatrice, López-Ramos, Miriam, Shoji, Kenji, Brys, Reginald, Amantini, David, Galien, René, Joannesse, Caroline

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Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Precli... von Mammoliti, Oscar, Palisse, Adeline, Joannesse, Caroline, El Bkassiny, Sandy, Allart, Brigitte, Jaunet, Alex, Menet, Christel, Coornaert, Beatrice, Sonck, Kathleen, Duys, Inge, Clément-Lacroix, Philippe, Oste, Line, Borgonovi, Monica, Wakselman, Emanuelle, Christophe, Thierry, Houvenaghel, Nicolas, Jans, Mia, Heckmann, Bertrand, Sanière, Laurent, Brys, Reginald

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Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor von Pardon, Marie, Claes, Pieter, Druwe, Sarah, Martini, Murielle, Siekierska, Aleksandra, Menet, Christel, de Witte, Peter A.M, Copmans, Danielle

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Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis von Van der Plas, Steven E, Kelgtermans, Hans, Mammoliti, Oscar, Menet, Christel, Tricarico, Giovanni, De Blieck, Ann, Joannesse, Caroline, De Munck, Tom, Lambin, Dominique, Cowart, Marlon, Dropsit, Sebastien, Martina, Sebastien L X, Gees, Maarten, Wesse, Anne-Sophie, Conrath, Katja, Andrews, Martin

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