Isoquercetin as an Anti-Covid-19 Medication: A Potential to Realize von Mbikay, Majambu, Chrétien, Michel

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60 YEARS OF POMC: From the prohormone theory to pro-opiomelanocortin and to proprotein convertases (PCSK1 to PCSK9) von Chrétien, Michel, Mbikay, Majambu

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The enigma of soluble LDLR: could inflammation be the key? von Mbikay, Majambu, Mayne, Janice, Chretien, Michel

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Quercetin inhibits SARS-CoV-2 infection and prevents syncytium formation by cells co-expressing the viral spike protein and human ACE2 von Roy, Annie V, Chan, Michael, Banadyga, Logan, He, Shihua, Zhu, Wenjun, Chrétien, Michel, Mbikay, Majambu

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Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages von Bissonnette, Simon, Lamantia, Valérie, Ouimet, Benjamin, Cyr, Yannick, Devaux, Marie, Rabasa-Lhoret, Remi, Chrétien, Michel, Saleh, Maya, Faraj, May

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The Effect of PCSK9 Loss-of-Function Variants on the Postprandial Lipid and ApoB-Lipoprotein Response von Ooi, Teik Chye, Krysa, Jacqueline A, Chaker, Seham, Abujrad, Hussein, Mayne, Janice, Henry, Kathy, Cousins, Marion, Raymond, Angela, Favreau, Colette, Taljaard, Monica, Chrétien, Michel, Mbikay, Majambu, Proctor, Spencer D, Vine, Donna F

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Plasma PCSK9 levels are significantly modified by statins and fibrates in humans von Mayne, Janice, Dewpura, Thilina, Raymond, Angela, Cousins, Marion, Chaplin, Anna, Lahey, Karen A, Lahaye, Stephen A, Mbikay, Majambu, Ooi, Teik Chye, Chrétien, Michel

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The Secretory Proprotein Convertase Neural Apoptosis-Regulated Convertase 1 (NARC-1): Liver Regeneration and Neuronal Differentiation von Seidah, Nabil G., Benjannet, Suzanne, Wickham, Louise, Marcinkiewicz, Jadwiga, Jasmin, Stéphanie Bélanger, Stifani, Stefano, Basak, Ajoy, Prat, Annik, Chrétien, Michel

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The loss-of-function PCSK9(Q152H) variant increases ER chaperones GRP78 and GRP94 and protects against liver injury von Lebeau, Paul F., Wassef, Hanny, Byun, Jae Hyun, Platko, Khrystyna, Ason, Brandon, Jackson, Simon, Dobroff, Joshua, Shetterly, Susan, Richards, William G., Al-Hashimi, Ali A., Won, Kevin Doyoon, Mbikay, Majambu, Prat, Annik, Tang, An, Pare, Guillaume, Pasqualini, Renata, Seidah, Nabil G., Arap, Wadih, Chretien, Michel, Austin, Richard C.

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Association of the rs562556 PCSK9 Gene Polymorphism with Reduced Mortality in Severe Malaria among Malian Children von Chrétien, Michel, Kouriba, Bouréma, Diarra, Issa, Arama, Charles, Fedoryak, Olesya, Mbikay, Majambu

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White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity von Cyr, Yannick, Bissonnette, Simon, Lamantia, Valérie, Wassef, Hanny, Loizon, Emmanuelle, Ngo Sock, Emilienne T., Vidal, Hubert, Mayer, Gaétan, Chrétien, Michel, Faraj, May

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Associations Between Soluble LDLR and Lipoproteins in a White Cohort and the Effect of PCSK9 Loss-of-Function von Mayne, Janice, Ooi, Teik Chye, Tepliakova, Lioudmila, Seebun, Deeptee, Walker, Krystal, Mohottalage, Dhanuddara, Ning, Zhibin, Abujrad, Hussein, Mbikay, Majambu, Wassef, Hanny, Chrétien, Michel, Figeys, Daniel

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Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children von Arama, Charles, Diarra, Issa, Kouriba, Bourèma, Sirois, Francine, Fedoryak, Olesya, Thera, Mahamadou A, Coulibaly, Drissa, Lyke, Kirsten E, Plowe, Christopher V, Chrétien, Michel, Doumbo, Ogobara K, Mbikay, Majambu

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Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake... von Mbikay, Majambu, Sirois, Francine, Simoes, Sonia, Mayne, Janice, Chrétien, Michel

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PCSK9: A Key Modulator of Cardiovascular Health von Seidah, Nabil G, Awan, Zuhier, Chrétien, Michel, Mbikay, Majambu

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Novel Loss-of-Function PCSK9 Variant Is Associated with Low Plasma LDL Cholesterol in a French-Canadian Family and with Impaired Processing and Secretion in Cell Culture von MAYNE, Janice, DEWPURA, Thilina, RAYMOND, Angela, BERNIER, Lise, COUSINS, Marion, CHYE OOI, Teik, DAVIGNON, Jean, SEIDAH, Nabil G, MBIKAY, Majambu, CHRETIEN, Michel

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Lower plasma PCSK9 in normocholesterolemic subjects is associated with upregulated adipose tissue surface‐expression of LDLR and CD36 and NLRP3 inflammasome von Cyr, Yannick, Lamantia, Valérie, Bissonnette, Simon, Burnette, Melanie, Besse‐Patin, Aurèle, Demers, Annie, Wabitsch, Martin, Chrétien, Michel, Mayer, Gaétan, Estall, Jennifer L., Saleh, Maya, Faraj, May

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Deletion of the Gene Encoding Proprotein Convertase 5/6 Causes Early Embryonic Lethality in the Mouse von Essalmani, Rachid, Hamelin, Josée, Marcinkiewicz, Jadwiga, Chamberland, Ann, Mbikay, Majambu, Chrétien, Michel, Seidah, Nabil G., Prat, Annik

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NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol von Benjannet, Suzanne, Rhainds, David, Essalmani, Rachid, Mayne, Janice, Wickham, Louise, Jin, Weijun, Asselin, Marie-Claude, Hamelin, Josée, Varret, Mathilde, Allard, Delphine, Trillard, Mélanie, Abifadel, Marianne, Tebon, Angie, Attie, Alan D, Rader, Daniel J, Boileau, Catherine, Brissette, Louise, Chrétien, Michel, Prat, Annik, Seidah, Nabil G

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Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro- matrix metalloproteinase-2 proteolytic cascade in atherosclerosis von STAWOWY, Philipp, MEYBORG, Heike, GRAF, Kristof, STIBENZ, Dietger, PEREIRA STAWOWY, Nubia Borges, ROSER, Mattias, THANABALASINGAM, Usan, VEINOT, John P, CHRETIEN, Michel, SEIDAH, Nabil G, FLECK, Eckart

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