Intradermal administration of DNA vaccine targeting Omicron SARS-CoV-2 via pyro-drive jet injector provides the prolonged neutralizing antibody production via germinal center react... von Hayashi, Hiroki, Sun, Jiao, Yanagida, Yuka, Otera, Takako, Tai, Jiayu A., Nishikawa, Tomoyuki, Yamashita, Kunihiko, Sakaguchi, Naoki, Yoshida, Shota, Baba, Satoshi, Chang, Chin Yang, Shimamura, Munehisa, Okamoto, Sachiko, Amaishi, Yasunori, Chono, Hideto, Mineno, Junichi, Rakugi, Hiromi, Morishita, Ryuichi, Nakagami, Hironori

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NY-ESO-1-specific redirected T cells with endogenous TCR knockdown mediate tumor response and cytokine release syndrome von Ishihara, Mikiya, Kitano, Shigehisa, Kageyama, Shinichi, Miyahara, Yoshihiro, Yamamoto, Noboru, Kato, Hidefumi, Mishima, Hideyuki, Hattori, Hiroyoshi, Funakoshi, Takeru, Kojima, Takashi, Sasada, Tetsuro, Sato, Eiichi, Okamoto, Sachiko, Tomura, Daisuke, Nukaya, Ikuei, Chono, Hideto, Mineno, Junichi, Kairi, Muhammad Faris, Diem Hoang Nguyen, Phuong, Simoni, Yannick, Nardin, Alessandra, Newell, Evan, Fehlings, Michael, Ikeda, Hiroaki, Watanabe, Takashi, Shiku, Hiroshi

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Modified DNA vaccine confers improved humoral immune response and effective virus protection against SARS-CoV-2 delta variant von Hayashi, Hiroki, Sun, Jiao, Yanagida, Yuka, Otera, Takako, Sasai, Miwa, Chang, Chin Yang, Tai, Jiayu A., Nishikawa, Tomoyuki, Yamashita, Kunihiko, Sakaguchi, Naoki, Yoshida, Shota, Baba, Satoshi, Shimamura, Munehisa, Okamoto, Sachiko, Amaishi, Yasunori, Chono, Hideto, Mineno, Junichi, Rakugi, Hiromi, Morishita, Ryuichi, Yamamoto, Masahiro, Nakagami, Hironori

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Highly Efficient Ultracentrifugation-free Chromatographic Purification of Recombinant AAV Serotype 9 von Tomono, Taro, Hirai, Yukihiko, Okada, Hironori, Miyagawa, Yoshitaka, Adachi, Kumi, Sakamoto, Shuhei, Kawano, Yasuhiro, Chono, Hideto, Mineno, Junichi, Ishii, Akiko, Shimada, Takashi, Onodera, Masafumi, Tamaoka, Akira, Okada, Takashi

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An efficient large-scale retroviral transduction method involving preloading the vector into a RetroNectin-coated bag with low-temperature shaking von Dodo, Katsuyuki, Chono, Hideto, Saito, Naoki, Tanaka, Yoshinori, Tahara, Kenichi, Nukaya, Ikuei, Mineno, Junichi

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Infectivity Assessment of Recombinant Adeno-Associated Virus and Wild-Type Adeno-Associated Virus Exposed to Various Diluents and Environmental Conditions von Tomono, Taro, Hirai, Yukihiko, Chono, Hideto, Mineno, Junichi, Ishii, Akiko, Onodera, Masafumi, Tamaoka, Akira, Okada, Takashi

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In vivo safety and persistence of endoribonuclease gene-transduced CD4+ T cells in cynomolgus macaques for HIV-1 gene therapy model von Chono, Hideto, Saito, Naoki, Tsuda, Hiroshi, Shibata, Hiroaki, Ageyama, Naohide, Terao, Keiji, Yasutomi, Yasuhiro, Mineno, Junichi, Kato, Ikunoshin

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CD4+ T Cells Modified by the Endoribonuclease MazF Are Safe and Can Persist in SHIV-infected Rhesus Macaques von Saito, Naoki, Chono, Hideto, Shibata, Hiroaki, Ageyama, Naohide, Yasutomi, Yasuhiro, Mineno, Junichi

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Optimization of lentiviral vector transduction into peripheral blood mononuclear cells in combination with the fibronectin fragment CH-296 stimulation von Chono, Hideto, Goto, Yumi, Yamakawa, Satoko, Tanaka, Shinya, Tosaka, Yasuhiro, Nukaya, Ikuei, Mineno, Junichi

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Safety and persistence of WT1-specific T-cell receptor gene−transduced lymphocytes in patients with AML and MDS von Tawara, Isao, Kageyama, Shinichi, Miyahara, Yoshihiro, Fujiwara, Hiroshi, Nishida, Tetsuya, Akatsuka, Yoshiki, Ikeda, Hiroaki, Tanimoto, Kazushi, Terakura, Seitaro, Murata, Makoto, Inaguma, Yoko, Masuya, Masahiro, Inoue, Naoki, Kidokoro, Tomohide, Okamoto, Sachiko, Tomura, Daisuke, Chono, Hideto, Nukaya, Ikuei, Mineno, Junichi, Naoe, Tomoki, Emi, Nobuhiko, Yasukawa, Masaki, Katayama, Naoyuki, Shiku, Hiroshi

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Induction of E. coli-derived endonuclease MazF suppresses HIV-1 production and causes apoptosis in latently infected cells von Okamoto, Mika, Chono, Hideto, Hidaka, Akemi, Toyama, Masaaki, Mineno, Junichi, Baba, Masanori

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Applications and Limitations of Equilibrium Density Gradient Analytical Ultracentrifugation for the Quantitative Characterization of Adeno-Associated Virus Vectors von Hirohata, Kiichi, Yamaguchi, Yuki, Maruno, Takahiro, Shibuya, Risa, Torisu, Tetsuo, Onishi, Takayuki, Chono, Hideto, Mineno, Junichi, Yuzhe, Yuan, Higashiyama, Kiyoko, Masumi-Koizumi, Kyoko, Uchida, Kazuhisa, Yamamoto, Takenori, Uchida, Eriko, Okada, Takashi, Uchiyama, Susumu

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Preclinical study of a DNA vaccine targeting SARS-CoV-2 von Hayashi, Hiroki, Sun, Jiao, Yanagida, Yuka, Otera, Takako, Kubota-Koketsu, Ritsuko, Shioda, Tatsuo, Ono, Chikako, Matsuura, Yoshiharu, Arase, Hisashi, Yoshida, Shota, Nakamaru, Ryo, Ju, Nan, Ide, Ryoko, Tenma, Akiko, Kawabata, Sotaro, Ehara, Takako, Sakaguchi, Makoto, Tomioka, Hideki, Shimamura, Munehisa, Okamoto, Sachiko, Amaishi, Yasunori, Chono, Hideto, Mineno, Junichi, Komatsuno, Takao, Saito, Yoshimi, Rakugi, Hiromi, Morishita, Ryuichi, Nakagami, Hironori

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The expression profile of microRNAs in mouse embryos von Mineno, Junichi, Okamoto, Sachiko, Ando, Tatsuya, Sato, Masahiro, Chono, Hideto, Izu, Hiroyuki, Takayama, Masanori, Asada, Kiyozo, Mirochnitchenko, Oleg, Inouye, Masayori, Kato, Ikunoshin

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Tumor responses and early onset cytokine release syndrome in synovial sarcoma patients treated with a novel affinity-enhanced NY-ESO-1-targeting TCR-redirected T cell transfer von Ishihara, Mikiya, Kitano, Shigehisa, Hattori, Hiroyoshi, Miyahara, Yoshihiro, Kato, Hidefumi, Mishima, Hideyuki, Yamamoto, Noboru, Funakoshi, Takeru, Kojima, Takashi, Sasada, Tetsuro, Sato, Eiichi, Okamoto, Sachiko, Tomura, Daisuke, Chono, Hideto, Nukaya, Ikuei, Mineno, Junichi, Ikeda, Hiroaki, Watanabe, Takashi, Kageyama, Shinichi, Shiku, Hiroshi

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Autologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals von Jacobson, Jeffrey M., Jadlowsky, Julie K., Lacey, Simon F., Fraietta, Joseph A., Plesa, Gabriela, Chono, Hideto, Lee, Dong H., Kulikovskaya, Irina, Bartoszek, Chelsie, Chen, Fang, Tian, Lifeng, Dimitri, Alexander, Levine, Bruce L., Veloso, Elizabeth A., Hwang, Wei-Ting, June, Carl H.

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Removal of Inhibitory Substances with Recombinant Fibronectin-CH-296 Plates Enhances the Retroviral Transduction Efficiency of CD34+CD38− Bone Marrow Cells von Chono, Hideto, Yoshioka, Hirofumi, Ueno, Mitsuhiro, Kato, Ikunoshin

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Engineering of CD19-CAR T Cells from Non-Hodgkin Lymphoma Patients in a Closed System in Combination with Retronectin/OKT3 Stimulation von Chono, Hideto, Tahara, Kenichi, Nukaya, Ikuei, Mineno, Junichi, Uehara, Eisuke, Tsukahara, Tomonori, Ohmine, Ken, Ozawa, Keiya, Takesako, Kazutoh

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Cytokine Release Syndrome and Tumor Responses in a First-in-Man Trial of a Novel Affinity-Enhanced TCR-Gene Transduced T Cell Transfer Targeting NY-ESO-1 Antigen von Kageyama, Shinichi, Ishihara, Mikiya, Kitano, Shigehisa, Miyahara, Yoshihiro, Kato, Hidefumi, Mishima, Hideyuki, Yamamoto, Noboru, Hattori, Hiroyoshi, Iwase, Hiroaki, Funakoshi, Takeru, Kojima, Takashi, Inoue, Naoki, Kidokoro, Tomohide, Tomura, Daisuke, Okamoto, Sachiko, Chono, Hideto, Nukaya, Ikuei, Mineno, Junichi, Ikeda, Hiroaki, Watanabe, Takashi, Shiku, Hiroshi

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Acquisition of HIV-1 Resistance in T Lymphocytes Using an ACA-Specific E. coli mRNA Interferase von CHONO, Hideto, MATSUMOTO, Kazuya, MINENO, Junichi, KIM, Sunyoung, INOUYE, Masayori, KATO, Ikunoshin, TSUDA, Hiroshi, SAITO, Naoki, LEE, Karim, KIM, Sujeong, SHIBATA, Hiroaki, AGEYAMA, Naohide, TERAO, Keiji, YASUTOMI, Yasuhiro

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