Therapeutic Effect of Ginsenoside Rd on Experimental Autoimmune Encephalomyelitis Model Mice: Regulation of Inflammation and Treg/Th17 Cell Balance von Liu, Mei, Geng, Yu, Zhang, Chixiao, Jin, Bo

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Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1) von Zhang, Zhimin, Chang, Xinyue, Zhang, Chixiao, Zeng, Shenxin, Liang, Meihao, Ma, Zhen, Wang, Zunyuan, Huang, Wenhai, Shen, Zhengrong

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(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling von Wang, Huanhuan, Huang, Wenhai, Liang, Meihao, Shi, Yingying, Zhang, Chixiao, Li, Qin, Liu, Meng, Shou, Yikai, Yin, Hongping, Zhu, Xiaozheng, Sun, Xiaoyan, Hu, Yu, Shen, Zhengrong

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Discovery of new non-covalent reversible BTK inhibitors: Synthesis, in silico studies, and in vitro evaluations von Wang, Zunyuan, Wang, Shu, Kang, Youkun, Chi, Xinglong, Pan, Youlu, Zeng, Shenxin, Zhang, Chixiao, Xu, Xiangwei, Wang, Wenyong, Huang, Wenhai

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Development of the “hidden” multifunctional agents for Alzheimer's disease von Huang, Wenhai, Liang, Meihao, Li, Qin, Zheng, Xiaoliang, Zhang, Chixiao, Wang, Qiao, Tang, Li, Zhang, Zhimin, Wang, Beibei, Shen, Zhengrong

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Novel phenanthridin-6(5H)-one derivatives as potent and selective BET bromodomain inhibitors: Rational design, synthesis and biological evaluation von Zhi, Yanle, Wang, Shu, Huang, Wenhai, Zeng, Shenxin, Liang, Meihao, Zhang, Chixiao, Ma, Zhen, Wang, Zunyuan, Zhang, Zhimin, Shen, Zhengrong

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HZ-A-005, a potent, selective, and covalent Bruton’s tyrosine kinase inhibitor in preclinical development von Huang, Wenhai, Wang, Shu, Zhang, Zhimin, Zhang, Chixiao, Zeng, Shenxin, Liang, Meihao, Shen, Zhengrong, Liu, Xingguo

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Progress on small-molecule proteolysis-targeting chimeras von Huang, Wenhai, Wang, Beibei, Zhang, Zhimin, Zhang, Chixiao, Zeng, Shenxin, Shen, Zhengrong

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Design, Synthesis, and Bioactivity of Novel Bifunctional Small Molecules for Alzheimer’s disease von Liang, Meihao, Gu, Lili, Zhang, Hongjie, Min, Jingli, Wang, Zunyuan, Ma, Zhen, Zhang, Chixiao, Zeng, Shenxin, Pan, Youlu, Yan, Dongmei, Shen, Zhengrong, Huang, Wenhai

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(1 R ,2 R )- N , N ′-Bis(ferrocenylmethyl)-1,2-diphenylethane-1,2-diamine von Guo, Yi, Wang, Jianfeng, Zhang, Chixiao, Luo, Shuping

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Compound with benzamide structure as well as preparation method and application of compound von PAN YOULU, ZENG SHENXIN, ZHANG CHIXIAO, WANG ZUNYUAN, HUANG WENHAI

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COMPOUND BASED ON CRBN LIGAND TO INDUCE DEGRADATION OF TAU PROTEIN, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF von WENHAI HUANG, ZUNYUAN WANG, LILI GU, SHENXIN ZENG, CHIXIAO ZHANG, MEIHAO LIANG, YOULU PAN, ZHENGRONG SHEN, ZHEN MA

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PI3K delta inhibitor as well as synthesis method and application thereof von LI QIN, PAN YOULU, ZENG SHENXIN, SHEN ZHENGRONG, ZHANG CHIXIAO, WANG ZUNYUAN, HUANG WENHAI

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(1R,2R)-N,N #8242;-Bis(ferrocenylmethyl)-1,2-diphenylethane-1,2-diamine von Yi Guo, Jianfeng Wang, Chixiao Zhang, Shuping Luo

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Preparation method of cyclobutene derivative von PAN YOULU, LI GANGJIAN, MA ZHEN, ZENG SHENXIN, SHEN ZHENGRONG, ZHANG CHIXIAO, WANG ZUNYUAN, HUANG WENHAI

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Irreversible BTK inhibitor with oxazolo [4, 5-b] pyridine structure and application of irreversible BTK inhibitor von LIANG MEIHAO, ZENG SHENXIN, SHEN ZHENGRONG, ZHANG CHIXIAO, WANG ZUNYUAN, HUANG WENHAI, WANG SHU

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Reversible BTK inhibitor as well as synthesis method and application thereof von LIANG MEIHAO, ZENG SHENXIN, SHEN ZHENGRONG, ZHANG CHIXIAO, WANG ZUNYUAN, HUANG WENHAI, WANG SHU

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Compound with PI3Kdelta/BTK double-target activity as well as preparation method and application of the compound von CHANG XINYUE, LIANG MEIHAO, ZENG SHENXIN, SHEN ZHENGRONG, ZHANG CHIXIAO, WANG ZUNYUAN, HUANG WENHAI

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Pyrazolo [3, 4-b] pyridine derivative, preparation method thereof and application of pyrazolo [3, 4-b] pyridine derivative as HPK1 inhibitor von PAN YOULU, LIANG MEIHAO, ZENG SHENXIN, SHEN ZHENGRONG, ZHANG CHIXIAO, WANG ZUNYUAN, HUANG WENHAI

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(1R,2R)-N,N'-Bis(ferrocenylmeth-yl)-1,2-diphenyl-ethane-1,2-diamine von Guo, Yi, Wang, Jianfeng, Zhang, Chixiao, Luo, Shuping

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