Antibody Structure and Function: The Basis for Engineering Therapeutics von Chiu, Mark L, Goulet, Dennis R, Teplyakov, Alexey, Gilliland, Gary L

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Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET von Neijssen, Joost, Cardoso, Rosa M.F., Chevalier, Kristen M., Wiegman, Luus, Valerius, Thomas, Anderson, G. Mark, Moores, Sheri L., Schuurman, Janine, Parren, Paul W.H.I., Strohl, William R., Chiu, Mark L.

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A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors von Moores, Sheri L, Chiu, Mark L, Bushey, Barbara S, Chevalier, Kristen, Luistro, Leopoldo, Dorn, Keri, Brezski, Randall J, Haytko, Peter, Kelly, Thomas, Wu, Sheng-Jiun, Martin, Pauline L, Neijssen, Joost, Parren, Paul W H I, Schuurman, Janine, Attar, Ricardo M, Laquerre, Sylvie, Lorenzi, Matthew V, Anderson, G Mark

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Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody von Zhang, Di, Goldberg, Monica V., Chiu, Mark L.

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A novel monoclonal antibody against human thymic stromal lymphopoietin for the treatment of TSLP-mediated diseases von Shi, Lihua, Yu, Mingcan, Jin, Ying, Chen, Peng, Mu, Guangmao, Tam, Susan H, Cho, Minseon, Tornetta, Mark, Han, Chao, Fung, Man-Cheong, Chiu, Mark L, Zhang, Di

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Engineering antibody therapeutics von Chiu, Mark L, Gilliland, Gary L

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Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models von Labrijn, Aran F., Meesters, Joyce I., Bunce, Matthew, Armstrong, Anthony A., Somani, Sandeep, Nesspor, Tom C., Chiu, Mark L., Altintaş, Işil, Verploegen, Sandra, Schuurman, Janine, Parren, Paul W. H. I.

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Large scale controlled Fab exchange GMP process to prepare bispecific antibodies von Yao, Xia, Xie, Mingquan, Ben, Yinyin, Zhu, Yixiang, Yang, Gaoqiang, Kwong, Simon Chi Wai, Zhang, Zhengliang, Chiu, Mark L

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Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality von Tam, Susan, McCarthy, Stephen, Armstrong, Anthony, Somani, Sandeep, Wu, Sheng-Jiun, Liu, Xuesong, Gervais, Alexis, Ernst, Robin, Saro, Dorina, Decker, Rose, Luo, Jinquan, Gilliland, Gary, Chiu, Mark, Scallon, Bernard

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A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function von Zhou, Fulai, Ben, Yinyin, Jiang, Hao, Tan, Siwen, Mu, Guangmao, Zha, Zhengxia, Dong, Shuting, Huang, Sheng, Zhou, Yijun, Jin, Ying, Chiu, Mark L.

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Phase 1 Safety and Pharmacokinetics Study of TAVO101, an Anti‐Human Thymic Stromal Lymphopoietin Antibody for the Treatment of Allergic Inflammatory Conditions von Han, Chao, Fung, Isa, Zhang, Di, Jin, Ying, Chen, Peng, Tam, Susan, Chiu, Mark L., Fung, Man‐Cheong

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Quantification of TRPV1 Protein Levels in Rat Tissues to Understand its Physiological Roles von Han, Ping, Korepanova, Alla V., Vos, Melissa H., Moreland, Robert B., Chiu, Mark L., Faltynek, Connie R.

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Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody von Hinke, Simon A., Cieniewicz, Anne M., Kirchner, Thomas, D'Aquino, Katharine, Nanjunda, Rupesh, Aligo, Jason, Perkinson, Robert, Cooper, Philip, Boayke, Ken, Chiu, Mark L., Jarantow, Steve, Lacy, Eilyn R., Liang, Yin, Johnson, Dana L., Whaley, Jean M., Lingham, Russell B., Kihm, Anthony J.

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Introduction to the Use of Linear and Nonlinear Regression Analysis in Quantitative Biological Assays von Jarantow, Stephen W., Pisors, Eileen D., Chiu, Mark L.

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Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors von Goulet, Dennis R., Zwolak, Adam, Williams, James A., Chiu, Mark L., Atkins, William M.

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Fc-mediated activity of EGFR x c-Met bispecific antibody JNJ-61186372 enhanced killing of lung cancer cells von Grugan, Katharine D, Dorn, Keri, Jarantow, Stephen W, Bushey, Barbara S, Pardinas, Jose R, Laquerre, Sylvie, Moores, Sheri L, Chiu, Mark L

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Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance von Goulet, Dennis R., Watson, Michael J., Tam, Susan H., Zwolak, Adam, Chiu, Mark L., Atkins, William M., Nath, Abhinav

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FcγRII-binding Centyrins mediate agonism and antibody-dependent cellular phagocytosis when fused to an anti-OX40 antibody von Zhang, Di, Whitaker, Brian, Derebe, Mehabaw G, Chiu, Mark L

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Human IgG subclass cross-species reactivity to mouse and cynomolgus monkey Fcγ receptors von Derebe, Mehabaw G., Nanjunda, Rupesh K., Gilliland, Gary L., Lacy, Eilyn R., Chiu, Mark L.

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Influence of the bispecific antibody IgG subclass on T cell redirection von Kapelski, Stephanie, Cleiren, Erna, Attar, Ricardo M, Philippar, Ulrike, Häsler, Julien, Chiu, Mark L

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