One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering von Yang, Hui, Wang, Haoyi, Shivalila, Chikdu S., Cheng, Albert W., Shi, Linyu, Jaenisch, Rudolf

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CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells von Liu, Xiaojuan, Zhang, Yongping, Cheng, Chen, Cheng, Albert W, Zhang, Xingying, Li, Na, Xia, Changqing, Wei, Xiaofei, Liu, Xiang, Wang, Haoyi

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Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase von Buganim, Yosef, Faddah, Dina A., Cheng, Albert W., Itskovich, Elena, Markoulaki, Styliani, Ganz, Kibibi, Klemm, Sandy L., van Oudenaarden, Alexander, Jaenisch, Rudolf

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Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction von Rudenko, Andrii, Dawlaty, Meelad M., Seo, Jinsoo, Cheng, Albert W., Meng, Jia, Le, Thuc, Faull, Kym F., Jaenisch, Rudolf, Tsai, Li-Huei

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Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations von Soldner, Frank, Laganière, Josée, Cheng, Albert W., Hockemeyer, Dirk, Gao, Qing, Alagappan, Raaji, Khurana, Vikram, Golbe, Lawrence I., Myers, Richard H., Lindquist, Susan, Zhang, Lei, Guschin, Dmitry, Fong, Lauren K., Vu, B. Joseph, Meng, Xiangdong, Urnov, Fyodor D., Rebar, Edward J., Gregory, Philip D., Zhang, H. Steve, Jaenisch, Rudolf

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One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering von Wang, Haoyi, Yang, Hui, Shivalila, Chikdu S., Dawlaty, Meelad M., Cheng, Albert W., Zhang, Feng, Jaenisch, Rudolf

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Loss of Tet Enzymes Compromises Proper Differentiation of Embryonic Stem Cells von Dawlaty, Meelad M., Breiling, Achim, Le, Thuc, Barrasa, M. Inmaculada, Raddatz, Günter, Gao, Qing, Powell, Benjamin E., Cheng, Albert W., Faull, Kym F., Lyko, Frank, Jaenisch, Rudolf

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CRISPR artificial splicing factors von Du, Menghan, Jillette, Nathaniel, Zhu, Jacqueline Jufen, Li, Sheng, Cheng, Albert Wu

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An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype von Shapiro, Irina M, Cheng, Albert W, Flytzanis, Nicholas C, Balsamo, Michele, Condeelis, John S, Oktay, Maja H, Burge, Christopher B, Gertler, Frank B

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system von Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf

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Transparent Real-Time Task Scheduling on Temporal Resource Partitions von Yu Li, Cheng, Albert M. K.

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Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development von Dawlaty, Meelad M., Breiling, Achim, Le, Thuc, Raddatz, Günter, Barrasa, M. Inmaculada, Cheng, Albert W., Gao, Qing, Powell, Benjamin E., Li, Zhe, Xu, Mingjiang, Faull, Kym F., Lyko, Frank, Jaenisch, Rudolf

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Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons von Li, Yun, Wang, Haoyi, Muffat, Julien, Cheng, Albert W., Orlando, David A., Lovén, Jakob, Kwok, Show-ming, Feldman, Danielle A., Bateup, Helen S., Gao, Qing, Hockemeyer, Dirk, Mitalipova, Maisam, Lewis, Caroline A., Vander Heiden, Matthew G., Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf

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Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development von Dawlaty, Meelad M., Ganz, Kibibi, Powell, Benjamin E., Hu, Yueh-Chiang, Markoulaki, Styliani, Cheng, Albert W., Gao, Qing, Kim, Jongpil, Choi, Sang-Woon, Page, David C., Jaenisch, Rudolf

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Solving Energy-Aware Real-Time Tasks Scheduling Problem with Shuffled Frog Leaping Algorithm on Heterogeneous Platforms von Zhang, Weizhe, Bai, Enci, He, Hui, Cheng, Albert M K

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Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs von Hanna, Jacob, Cheng, Albert W, Saha, Krishanu, Kim, Jongpil, Lengner, Christopher J, Soldner, Frank, Cassady, John P, Muffat, Julien, Carey, Bryce W, Jaenisch, Rudolf

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Histone H3K27ac separates active from poised enhancers and predicts developmental state von Creyghton, Menno P., Cheng, Albert W., Welstead, G. Grant, Kooistra, Tristan, Carey, Bryce W., Steine, Eveline J., Hanna, Jacob, Lodato, Michael A., Frampton, Garrett M., Sharp, Phillip A., Boyer, Laurie A., Young, Richard A., Jaenisch, Rudolf

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Regularity-Based Virtualization Under the ARINC 653 Standard for Embedded Systems von Dai, Guangli, Paluri, Pavan Kumar, Cheng, Albert Mo Kim, Liu, Bozheng

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Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts von Kim, Jongpil, Su, Susan C., Wang, Haoyi, Cheng, Albert W., Cassady, John P., Lodato, Michael A., Lengner, Christopher J., Chung, Chee-Yeun, Dawlaty, Meelad M., Tsai, Li-Huei, Jaenisch, Rudolf

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SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state von Lodato, Michael A, Ng, Christopher W, Wamstad, Joseph A, Cheng, Albert W, Thai, Kevin K, Fraenkel, Ernest, Jaenisch, Rudolf, Boyer, Laurie A

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